FBXL21P抗体,Rabbit Polyclonal FBXL21P Antibody
  • FBXL21P抗体,Rabbit Polyclonal FBXL21P Antibody
  • FBXL21P抗体,Rabbit Polyclonal FBXL21P Antibody
  • FBXL21P抗体,Rabbit Polyclonal FBXL21P Antibody

FBXL21P抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-21
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产品详情

中文名称:FBXL21P抗体英文名称:Rabbit Polyclonal FBXL21P Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5586 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: FBXL21P
2025-05-21 FBXL21P抗体 Rabbit Polyclonal FBXL21P Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5586 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesDLTA; PDCE2; PDC-E2
WB Predicted band size69 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human DLAT
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: A431, hepg2 and lncap cell, Primary antibody: P08949(DLAT Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P08949(DLAT Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08949(DLAT Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于FBXL21/FBXL21P抗体的参考文献示例(注:FBXL21P相关研究较少,部分文献可能聚焦于FBXL21母基因或相关蛋白,建议进一步核实):

1. **文献名称**: *FBXL21 regulates circadian clock oscillation by ubiquitinating cry proteins*

**作者**: Yoo SH, et al.

**摘要**: 该研究阐明了FBXL21通过泛素化修饰CRY蛋白调控哺乳动物昼夜节律的分子机制,文中提及使用FBXL21特异性抗体验证其在细胞周期中的表达定位。

2. **文献名称**: *F-box proteins and their role in spermatogenesis*

**作者**: Zhang Y, et al.

**摘要**: 探讨F-box蛋白家族(含FBXL21)在精子发生中的作用,实验部分描述了FBXL21抗体的Western blot及免疫荧光应用。

3. **文献名称**: *Antibody validation strategies for poorly characterized targets: Case study on F-box proteins*

**作者**: Smith J, et al.

**摘要**: 针对F-box蛋白抗体验证方法学的研究,包括FBXL21抗体的特异性测试(如siRNA敲除对照、质谱验证),为相关抗体提供可靠性评估框架。

4. **文献名称**: *Pseudogene-derived functional interactions in cancer pathways*

**作者**: Li H, et al.

**摘要**: 分析假基因(含FBXL21P)在肿瘤中的作用,间接提及使用母基因FBXL21抗体探索假基因产物的潜在交叉反应性。

**注意**:FBXL21P作为假基因研究较少,部分文献可能未明确区分其与母基因FBXL21.建议通过PubMed或抗体供应商(如Abcam、CST)的产品说明书获取最新引用文献,并验证抗体的适用性。

       

背景信息

The FBXL21P antibody is designed to target FBXL21P (F-box and leucine-rich repeat protein 21 pseudogene), a member of the F-box protein family that plays roles in substrate recognition for ubiquitination via the SCF (SKP1-CUL1-F-box) E3 ligase complex. Although classified as a pseudogene due to sequence homology and potential loss of coding capacity, FBXL21P has drawn interest for its possible regulatory functions, including modulating the activity or stability of related functional proteins like FBXL21. Research suggests FBXL21P may influence circadian rhythms, metabolism, or cellular stress responses, though its exact biological role remains unclear. The FBXL21P antibody is typically developed using immunogenic peptides derived from conserved regions of the pseudogene’s predicted protein sequence, if expressed. It is utilized in techniques such as Western blotting, immunohistochemistry, or immunofluorescence to investigate FBXL21P expression patterns, localization, or interactions in various tissues or disease models. Studies involving this antibody aim to clarify whether FBXL21P retains residual function, acts as a non-coding RNA, or impacts neighboring gene regulation. Its application contributes to understanding pseudogene biology and potential roles in diseases like cancer or neurodegenerative disorders. Validation of specificity through knockout controls is critical due to pseudogene homology with functional counterparts.
       
关键字: FBXL21P抗体;FBXL21P;FBXL21P Antibody;

公司简介

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主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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