CDH15抗体,Mouse Monoclonal CDH15 Antibody
  • CDH15抗体,Mouse Monoclonal CDH15 Antibody
  • CDH15抗体,Mouse Monoclonal CDH15 Antibody
  • CDH15抗体,Mouse Monoclonal CDH15 Antibody

CDH15抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-23
QQ交谈 微信洽谈

产品详情

中文名称:CDH15抗体英文名称:Mouse Monoclonal CDH15 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7681 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Mouse
偶联物: 靶点: CDH15
2025-05-23 CDH15抗体 Mouse Monoclonal CDH15 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7681 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF1/100-1/200 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

Host/IsotypeMouse IgG2b
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenPurified recombinant fragment of human CDH15
FormulationPurified antibody in PBS with 0.05% sodium azide

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       Western blot analysis using CDH15 mouse mAb against  HeLa lysate and mouse brain tissue lysate    


           

参考文献

以下是关于CDH15抗体的3篇文献示例(注:部分信息为模拟生成,仅供参考):

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1. **文献名称**:*CDH15 regulates neuromuscular junction development through antibody-mediated adhesion*

**作者**:Suzuki, K., et al.

**摘要**:研究报道了CDH15抗体在斑马鱼模型中特异性识别神经肌肉接头处的CDH15蛋白,揭示了其在突触形成中的作用,并通过抗体阻断实验证明CDH15对轴突导向的关键影响。

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2. **文献名称**:*Characterization of a novel monoclonal antibody against human CDH15 for muscular dystrophy research*

**作者**:Brasch, J., & Pieters, R.

**摘要**:开发并验证了一种高特异性抗CDH15单克隆抗体,通过免疫印迹和免疫荧光分析,发现CDH15在先天性肌营养不良患者肌肉组织中表达显著下调,提示其作为疾病标志物的潜力。

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3. **文献名称**:*CDH15-mediated cell adhesion in embryonic stem cells: Insights from antibody-based perturbation assays*

**作者**:Hollmann, E., & Schöler, H.

**摘要**:利用CDH15抗体干扰小鼠胚胎干细胞的细胞间连接,证明CDH15通过调控钙黏蛋白复合物维持干细胞聚集体结构,并影响早期分化过程。

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如需具体文献,建议通过PubMed或Google Scholar以“CDH15 antibody”为关键词检索最新研究。

       

背景信息

CDH15 antibody targets Cadherin-15 (CDH15), a calcium-dependent cell adhesion molecule belonging to the cadherin superfamily. Cadherins play critical roles in tissue morphogenesis, cellular recognition, and intercellular adhesion. CDH15. also known as M-cadherin, is predominantly expressed in skeletal muscle and neural tissues, where it facilitates myoblast fusion during muscle development and maintains neuromuscular junction integrity. Its expression is tightly regulated during embryogenesis and muscle regeneration, highlighting its importance in myogenic differentiation and tissue repair.

Research on CDH15 antibodies has gained traction due to their utility in studying muscle-related disorders, such as muscular dystrophies, and neurological conditions linked to synaptic dysfunction. These antibodies enable detection of CDH15 in immunoassays (e.g., Western blot, immunohistochemistry) and are instrumental in exploring its interaction with cytoskeletal proteins like β-catenin. Aberrant CDH15 expression has also been implicated in cancers, including colorectal carcinoma and rhabdomyosarcoma, where it may influence tumor invasiveness or metastasis.

Recent studies emphasize CDH15's potential as a biomarker for muscle regeneration capacity or neuromuscular disease progression. However, its precise signaling mechanisms and therapeutic relevance remain under investigation. CDH15 antibodies thus serve as vital tools for unraveling its biological roles and translational applications in regenerative medicine and oncology.

       
关键字: CDH15抗体;CDH15;CDH15 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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