SAMD13抗体—艾普蒂 新品

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     IHC-P analysis of colon tissue by SAMD13 antibody (P15971) IHC-P was performed using sections of the formalin-fixed paraffin-embedded colon tissue;Result: Glandular cells and cells in lamina propria are positively stained at the cytoplasm.    

  
  

The SAMD13 (Sterile Alpha Motif Domain-containing 13) antibody is a tool used to detect and study the SAMD13 protein, a member of the SAM domain-containing protein family. SAM domains are evolutionarily conserved protein modules involved in protein-protein interactions, often regulating diverse cellular processes such as signal transduction, transcriptional regulation, and apoptosis. SAMD13. though less characterized compared to other SAM domain proteins, is implicated in immune responses and cancer biology. Studies suggest its potential role in modulating inflammatory pathways and tumor progression, with altered expression observed in certain cancers, including hepatocellular carcinoma and glioblastoma.

The SAMD13 antibody is typically developed using immunogens derived from specific epitopes of the human SAMD13 protein. It enables researchers to investigate SAMD13's expression patterns, subcellular localization, and interactions via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Its applications extend to both basic research and clinical studies, particularly in understanding SAMD13's functional mechanisms in disease contexts. However, comprehensive biological roles of SAMD13 remain under exploration, necessitating further validation of antibody specificity and functional studies. Commercial SAMD13 antibodies are available from various suppliers, often accompanied by validation data in common cell lines or tissues. Researchers should optimize experimental conditions to ensure reproducibility across different models.