CD5L抗体,Rabbit Polyclonal CD5L Antibody
  • CD5L抗体,Rabbit Polyclonal CD5L Antibody
  • CD5L抗体,Rabbit Polyclonal CD5L Antibody
  • CD5L抗体,Rabbit Polyclonal CD5L Antibody

CD5L抗体;CD5L Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
QQ交谈 微信洽谈

产品详情

中文名称:CD5L抗体英文名称:Rabbit Polyclonal CD5L Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6186 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CD5L
2025-05-26 CD5L抗体 Rabbit Polyclonal CD5L Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6186 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesAIM; API6; PRO229; Spalpha; SP-ALPHA
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human CD5L
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human Lymphoma tissue using P11648(CD5L Antibody) at dilution 1/40. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11648(CD5L Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于CD5L抗体的示例性参考文献(注:内容为模拟示例,非真实文献):

1. **标题**:*CD5L Antibody Attenuates Liver Fibrosis via Modulating Macrophage Polarization*

**作者**:Zhang Y, et al.

**摘要**:研究利用抗CD5L抗体在小鼠肝纤维化模型中干预,发现其通过抑制促炎性巨噬细胞活化,促进M2型极化,显著减少胶原沉积,提示CD5L抗体在纤维化疾病中的治疗潜力。

2. **标题**:*Therapeutic Targeting of CD5L in Rheumatoid Arthritis with Humanized Monoclonal Antibodies*

**作者**:Smith J, et al.

**摘要**:开发人源化抗CD5L单克隆抗体,在类风湿性关节炎模型中验证其疗效,结果显示抗体通过阻断CD5L与凋亡细胞结合,降低炎症因子水平并缓解关节损伤。

3. **标题**:*CD5L as a Biomarker in Metabolic Syndrome: Insights from Antibody-Based Detection*

**作者**:Lee H, et al.

**摘要**:通过抗CD5L抗体检测血浆CD5L水平,发现其与肥胖患者的胰岛素抵抗和脂肪组织炎症呈正相关,提示CD5L可作为代谢综合征的潜在生物标志物。

4. **标题**:*Structural Basis of CD5L Recognition by Neutralizing Antibodies in Atherosclerosis*

**作者**:Garcia-Ruiz C, et al.

**摘要**:解析CD5L蛋白与中和抗体的复合物结构,揭示抗体通过阻断CD5L与氧化低密度脂蛋白结合,抑制动脉粥样硬化斑块形成,为抗体药物开发提供依据。

(注:以上文献信息为模拟生成,实际引用时需以真实数据库检索结果为准。)

       

背景信息

CD5L (CD5 Antigen-Like), also known as APRIL or CD5L, is a secreted glycoprotein belonging to the scavenger receptor cysteine-rich (SRCR) superfamily. Primarily expressed in immune cells like macrophages, dendritic cells, and specific lymphocyte subsets, it plays regulatory roles in inflammation, apoptosis, and lipid metabolism. Its structure includes conserved SRCR domains that mediate interactions with cell surface receptors such as CD5 and TLT-1. influencing immune signaling pathways.

CD5L antibodies are critical tools for studying its dual roles in disease contexts. In autoimmune disorders (e.g., rheumatoid arthritis), CD5L may suppress excessive inflammation by modulating macrophage activity. Conversely, in chronic infections or cancers, it might promote immune evasion by altering cytokine profiles in the tumor microenvironment. Its involvement in lipid homeostasis also links CD5L to metabolic diseases; elevated levels correlate with atherosclerosis progression through lipid-laden macrophage formation.

Research applications of CD5L antibodies include immunohistochemistry, flow cytometry, and functional blocking assays to dissect its mechanisms. Therapeutic potential is being explored, with antibody-based strategies aiming to either neutralize CD5L in pro-inflammatory conditions or enhance its activity in metabolic syndromes. Despite progress, its context-dependent functions require careful targeting to avoid paradoxical effects. Ongoing studies focus on tissue-specific expression patterns and receptor cross-talk to refine clinical applications.

       
关键字: CD5L抗体;CD5L;CD5L Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

CD5L抗体;CD5L Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1180
VIP1年
上海西格生物科技有限公司
2026-01-16
¥1180
VIP1年
上海抚生实业有限公司
2026-01-16
¥1180
VIP1年
上海博湖生物科技有限公司
2026-01-16
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.