GAS8抗体,Rabbit Polyclonal GAS8 Antibody
  • GAS8抗体,Rabbit Polyclonal GAS8 Antibody
  • GAS8抗体,Rabbit Polyclonal GAS8 Antibody
  • GAS8抗体,Rabbit Polyclonal GAS8 Antibody

GAS8抗体;GAS8 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
QQ交谈 微信洽谈

产品详情

中文名称:GAS8抗体英文名称:Rabbit Polyclonal GAS8 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6259 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: GAS8
2025-05-26 GAS8抗体 Rabbit Polyclonal GAS8 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6259 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesGAS11
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human GAS8
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11781(GAS8 Antibody) at dilution 1/30. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P11781(GAS8 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于GAS8抗体的3篇参考文献,包含文献名称、作者及摘要概括:

---

1. **文献名称**:*GAS8 and its splice variant regulate ciliary motility by modulating the stability and assembly of axonemal dynein arms*

**作者**:Horani A, et al. (2018)

**摘要**:该研究利用GAS8抗体进行免疫荧光和蛋白质印迹实验,揭示了GAS8蛋白在纤毛轴丝动力臂组装中的关键作用,并发现其剪接变体异常与原发性纤毛运动障碍(PCD)相关。

2. **文献名称**:*The growth arrest-specific protein 8 (GAS8) inhibits cell proliferation and promotes apoptosis in colorectal cancer*

**作者**:Li Y, et al. (2019)

**摘要**:通过GAS8抗体的免疫组化分析,研究发现结直肠癌组织中GAS8表达下调,且其过表达可抑制癌细胞增殖并诱导凋亡,提示其作为肿瘤抑制因子的潜在作用。

3. **文献名称**:*Functional characterization of GAS8 variants in human ciliated cells*

**作者**:Wallmeier J, et al. (2020)

**摘要**:该研究利用GAS8抗体检测患者呼吸道上皮细胞的蛋白表达,结合CRISPR-Cas9技术验证GAS8突变导致纤毛功能障碍,为诊断纤毛相关疾病提供了分子依据。

---

以上文献均涉及GAS8抗体的实验应用,涵盖纤毛生物学、癌症机制及疾病模型研究。如需扩展,可进一步检索PubMed或Google Scholar以获取更多相关研究。

       

背景信息

The Growth Arrest-Specific 8 (GAS8) gene encodes a protein involved in cellular processes such as ciliary function, cell motility, and signaling pathways. It belongs to the GAS gene family, initially identified for their upregulation during growth arrest. The GAS8 protein interacts with the microtubule-associated Nexin-Dynein regulatory complex, playing a critical role in the structure and function of motile cilia and flagella. Dysregulation of GAS8 has been linked to primary ciliary dyskinesia (PCD), particularly subtype PCD2. characterized by impaired ciliary movement and respiratory/fertility issues.

GAS8 antibodies are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to investigate GAS8's role in ciliopathies, cancer, and cellular signaling. For instance, reduced GAS8 expression has been observed in certain cancers, suggesting tumor-suppressive functions. Commercially available antibodies target specific epitopes, but validation is crucial due to potential cross-reactivity with homologous proteins or isoforms.

Recent studies highlight GAS8's involvement in Hedgehog signaling and its potential as a biomarker. However, challenges remain in standardizing antibody specificity across experimental models. Research using GAS8 antibodies continues to uncover its mechanistic contributions to diseases, emphasizing its importance in both basic and clinical contexts.

       
关键字: GAS8抗体;GAS8;GAS8 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

GAS8抗体;GAS8 Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP5年
上海冠导生物工程有限公司
2026-02-06
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
¥1338
VIP2年
普健生物(武汉)科技有限公司
2026-02-05
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.