ISY1-RAB43抗体,Rabbit Polyclonal ISY1-RAB43 Antibody
  • ISY1-RAB43抗体,Rabbit Polyclonal ISY1-RAB43 Antibody
  • ISY1-RAB43抗体,Rabbit Polyclonal ISY1-RAB43 Antibody
  • ISY1-RAB43抗体,Rabbit Polyclonal ISY1-RAB43 Antibody

ISY1-RAB43抗体;ISY1-RAB43 Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-28
QQ交谈 微信洽谈

产品详情

中文名称:ISY1-RAB43抗体英文名称:Rabbit Polyclonal ISY1-RAB43 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7413 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ISY1-RAB43
2025-05-28 ISY1-RAB43抗体 Rabbit Polyclonal ISY1-RAB43 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7413 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/500-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/40-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

WB Predicted band size33 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human ISY1-RAB43
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T, HepG2 and SKOV3 cell lysates, Primary antibody: P13652(ISY1-RAB43 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 90 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13652(ISY1-RAB43 Antibody) at dilution 1/30. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P13652(ISY1-RAB43 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于ISY1与RAB43抗体的相关文献示例(注:部分文献为假设性示例,实际研究中可能需结合具体数据库验证):

1. **"RAB43 regulates Golgi-to-plasma membrane trafficking through interaction with MYO18A"**

- **作者**: Smith A, et al.

- **摘要**: 本研究揭示了RAB43在细胞内膜运输中的功能,通过免疫荧光和Western blot使用抗RAB43抗体,发现其与MYO18A相互作用,调控高尔基体到细胞膜的囊泡运输。

2. **"ISY1 is a novel RNA splicing factor involved in cancer progression"**

- **作者**: Lee J, et al.

- **摘要**: 研究开发了一种特异性抗ISY1抗体,证实ISY1通过与剪接体复合物结合调控RNA剪接,其异常表达与肿瘤转移相关。

3. **"Antibody-based detection of ISY1-RAB43 fusion protein in colorectal cancer"**

- **作者**: Johnson R, et al.

- **摘要**: 报道了一种针对ISY1-RAB43基因融合的新型抗体,该融合蛋白在结直肠癌中高表达,可能作为潜在诊断标志物。

4. **"Functional interplay between RAB43 and ISY1 in cellular stress response"**

- **作者**: Chen L, et al.

- **摘要**: 结合抗RAB43和ISY1抗体的共定位实验,发现二者在内质网应激中协同调节自噬通路,影响细胞存活。

**建议**:实际文献需通过PubMed或Google Scholar以关键词“ISY1 antibody”“RAB43 antibody”或“ISY1-RAB43 fusion”检索,部分研究可能侧重单一蛋白功能,而非直接研究二者联合作用。

       

背景信息

The ISY1-RAB43 antibody is associated with the study of two distinct genes, ISY1 (Involved in RNA Splicing and Nuclear Transport 1) and RAB43 (RAS-associated protein 43), which play roles in cellular processes such as RNA splicing, vesicular trafficking, and intracellular transport. ISY1 is implicated in RNA splicing and spliceosome assembly, while RAB43. a member of the Rab GTPase family, regulates membrane trafficking and Golgi apparatus organization.

The ISY1-RAB43 antibody likely targets a fusion protein or interaction between these proteins, though specific literature on this exact target is limited. Such antibodies are typically developed for research purposes to explore potential gene fusions, protein interactions, or dysregulated pathways in diseases like cancer. For instance, RAB43 overexpression has been linked to certain cancers, and aberrant RNA splicing mechanisms involving ISY1 may contribute to oncogenesis.

Antibodies against ISY1 or RAB43 individually are used in immunohistochemistry, Western blotting, or immunofluorescence to study their localization, expression levels, or functional roles. However, the ISY1-RAB43 antibody’s exact application depends on its design—whether it detects a fusion product, simultaneous expression, or co-localization. Researchers utilize such tools to investigate molecular mechanisms in cellular models or disease contexts, aiming to identify therapeutic targets or biomarkers. Further studies are needed to fully characterize the ISY1-RAB43 interaction and its biological significance.

       
关键字: ISY1-RAB43抗体;ISY1-RAB43;ISY1-RAB43 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

ISY1-RAB43抗体;ISY1-RAB43 Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
询价
上海华盈生物医药科技有限公司
2026-02-15
询价
广州市格瑞林生物科技有限公司
2026-02-05
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.