Lactoferrin抗体;Lactoferrin Antibody—艾普蒂 新品

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     Western blot analysis of Lactoferrin expression in HeLa cell lysate.    

  
  

Lactoferrin antibodies are immunological tools developed to target lactoferrin, a multifunctional iron-binding glycoprotein belonging to the transferrin family. Lactoferrin is naturally present in mammalian secretions like milk, saliva, and tears, and plays critical roles in innate immunity, antimicrobial defense, and iron homeostasis. Its involvement in immune regulation, anti-inflammatory responses, and cell proliferation has made it a subject of interest in both basic research and clinical applications.

Antibodies against lactoferrin are typically polyclonal or monoclonal, produced by immunizing animals with purified lactoferrin. These antibodies enable the detection and quantification of lactoferrin in biological samples using techniques like ELISA, Western blotting, or immunohistochemistry. They are widely used to study lactoferrin's expression patterns in health and disease, such as infections, autoimmune disorders, or cancer.

Clinically, lactoferrin antibodies aid in diagnosing conditions where lactoferrin levels serve as biomarkers, such as inflammatory bowel disease (IBD) or sepsis. Additionally, they are explored for therapeutic potential, including blocking pathogenic interactions or modulating immune responses. Challenges include ensuring antibody specificity due to lactoferrin's structural similarity to other transferrins. Ongoing research focuses on refining antibody-based assays and therapeutic strategies targeting lactoferrin's diverse biological functions.