NeuroD2抗体;NeuroD2 Antibody—艾普蒂 新品

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     All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    

  
  

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     Western blot analysis of NeuroD2 expression in mouse cerebellum cell lysate.    

  
  

The NeuroD2 antibody is a crucial tool in neuroscience research, targeting the Neurogenic Differentiation Factor 2 (NeuroD2), a basic helix-loop-helix (bHLH) transcription factor. NeuroD2 plays a pivotal role in neuronal differentiation, survival, and synaptic plasticity during brain development. It is predominantly expressed in the central nervous system, particularly in the cerebral cortex, hippocampus, and cerebellum. Dysregulation of NeuroD2 has been linked to neurodevelopmental disorders, epilepsy, and brain tumors like medulloblastoma.

The NeuroD2 antibody enables researchers to detect and quantify NeuroD2 protein levels in various experimental models, including immunohistochemistry (IHC), Western blot (WB), and immunofluorescence (IF). It is commonly used to study neurogenesis, neuronal maturation, and disease mechanisms. Many commercially available NeuroD2 antibodies are raised in host species like rabbit or mouse, validated for specificity using knockout controls or recombinant protein assays. Some antibodies target specific epitopes, such as the N-terminal or C-terminal regions, to accommodate diverse experimental needs. Recent studies also employ NeuroD2 antibodies to investigate its interactions with chromatin modifiers or its role in regulating target genes like *Grina* and *Nptx2*. Proper validation and optimization remain essential due to potential cross-reactivity with related proteins like NeuroD1 or tissue-specific expression variations.