gamma Tubulin抗体,Mouse Monoclonal gammaTubulin Antibody
  • gamma Tubulin抗体,Mouse Monoclonal gammaTubulin Antibody
  • gamma Tubulin抗体,Mouse Monoclonal gammaTubulin Antibody
  • gamma Tubulin抗体,Mouse Monoclonal gammaTubulin Antibody

gamma Tubulin抗体;gamma Tubulin Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-06-03
QQ交谈 微信洽谈

产品详情

中文名称:gamma Tubulin抗体英文名称:Mouse Monoclonal gammaTubulin Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 9127 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Mouse
偶联物: 靶点: gamma Tubulin
2025-06-03 gamma Tubulin抗体 Mouse Monoclonal gammaTubulin Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 9127 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesTUBG1; TUBG; Tubulin gamma-1 chain; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1
Entrez GeneID7283
clone2A5
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide conjugated to KLH.
FormulationPurified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

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       Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using gamma Tubulin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.    


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       Immunohistochemical analysis of paraffin-embedded Human tonsils using gamma Tubulin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.    


           

参考文献

以下是关于γ-Tubulin抗体的3篇代表性文献,涵盖其功能及抗体应用研究:

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1. **文献名称**:*γ-Tubulin is a highly conserved component of the centrosome*

**作者**:Oakley, B. R., & Oakley, C. E. (1990)

**摘要**:首次报道γ-Tubulin抗体在真菌中的开发,证实其在微管组织中心(MTOC)的定位,证明γ-Tubulin在微管成核中的核心作用,为后续研究奠定基础。

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2. **文献名称**:*γ-Tubulin regulates microtubule nucleation in mammalian cells*

**作者**:Luders, J., Stearns, T., & King, R. W. (2005)

**摘要**:通过γ-Tubulin抗体结合免疫荧光技术,揭示哺乳动物细胞中γ-Tubulin复合体(γ-TuRC)调控微管形成的分子机制,并验证抗体在功能抑制实验中的有效性。

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3. **文献名称**:*Differential requirements of γ-Tubulin for mitotic progression in budding yeast and green algae*

**作者**:Horio, T., & Ueda, K. (2002)

**摘要**:对比研究γ-Tubulin在不同模式生物(酵母、绿藻)有丝分裂中的作用,利用特异性抗体进行定位分析,揭示物种间功能差异及抗体在跨物种研究中的适用性。

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**备注**:如需更详细的引用信息(期刊、卷号等)或近年研究,建议通过PubMed或Google Scholar以“gamma tubulin antibody”为关键词检索,重点关注高引论文或方法学相关文章(如抗体验证、新型检测技术)。

       

背景信息

Gamma tubulin is a conserved member of the tubulin superfamily, primarily localized at microtubule-organizing centers (MTOCs) such as centrosomes. It plays a critical role in microtubule nucleation and spindle formation during cell division by serving as a structural platform for γ-tubulin ring complexes (γ-TuRCs). These complexes template the assembly of α/β-tubulin dimers into microtubules, essential for maintaining cell shape, intracellular transport, and chromosomal segregation. Dysregulation of gamma tubulin is linked to mitotic errors, genomic instability, and diseases including cancer and neurodegenerative disorders.

Gamma tubulin antibodies are indispensable tools for studying MTOC dynamics, cell cycle regulation, and microtubule-related pathologies. Commonly used in immunofluorescence, Western blotting, and immunoprecipitation, these antibodies help visualize gamma tubulin distribution in mitotic structures, cilia, or centrosome abnormalities. Monoclonal antibodies like the widely cited GTU-88 clone specifically recognize conserved epitopes across species (human, mouse, rat), enabling cross-species applications. Commercial gamma tubulin antibodies are often validated for specificity using knockout (KO) cell lines or siRNA knockdown. Researchers also employ them as loading controls in centriole/centrosome studies. However, interpretation requires caution due to potential cross-reactivity with other tubulin isoforms or epitope masking in certain conformational states. High-quality antibodies are available from suppliers such as Sigma-Aldrich, Abcam, and Cell Signaling Technology.

       
关键字: gamma Tubulin抗体;gamma Tubulin;gamma Tubulin Antibo;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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