Alexa Fluor™ 647-Labeled Human BCMA / TNFRSF17 Protein, His Tag
分子别名（Synonym）
TNFRSF17, CD269, BCM, BCMA
表达区间及表达系统（Source）
Alexa Fluor 647-Labeled Human BCMA, His Tag (BCA-HA2H9) is produced via conjugation of AF647 to Human BCMA, His Tag with a new generation site-specific technology under Star Staining labeling platform. Human BCMA, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # Q02223-1).
Predicted N-terminus: Met 1
蛋白结构（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus.
偶联（Conjugate）
AF647
Excitation Wavelength: 640 nm
Emission Wavelength: 672 nm
纯度（Purity）
>90% as determined by SDS-PAGE.
制剂（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景介绍
肿瘤坏死因子受体超家族成员17（TNFRSF17）亦称为B细胞成熟蛋白（BCMA）或CD269抗原，是肿瘤坏死因子受体超家族的重要成员。该蛋白包含一个TNFR-Cys重复结构域，特异性表达于成熟B细胞表面，而在T细胞及单核细胞中不表达。TNFRSF17作为TNFSF13B/BLyS/BAFF和TNFSF13/APRIL的受体，能够促进B细胞存活并参与体液免疫调节。该受体可激活NF-κB及JNK信号通路。
关键字： BCMA;BCMA蛋白;BCMA重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group（股票代码：301080）是成立于2010年的跨国生物科技公司，是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球，横跨亚洲、北美洲、欧洲，在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家，与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。