Product Name：PIC1 PA
CAS No.：1356469-36-7
Synonyms：PIC1类似物多肽
Catalog No.：220P070
Brand：Typeptide Biotech（肽研生物）
Description：PIC1 PA是由15个氨基酸组成的多肽，是一种有效的PIC1类似物，可以抑制经典途径介导的补体激活。PIC1 PA 分别在功能上破坏 C1s-C1r-C1r-C1s/MASPs 与 C1q/MBL 的胶原样区 (CLR) 的相互作用。PIC1 PA 特异性结合 C1q 的 CLR，结合纯化的 C1q 的平均平衡解离常数 (KD) 为 33.3 nM。
The PIC1 PA is a 15 - amino - acid - long peptide that acts as an effective analog of PIC1. It can inhibit the activation of the complement system mediated by the classical pathway. PIC1 PA disrupts the interaction between the collagen - like region (CLR) of C1q/MBL and the C1s - C1r - C1r - C1s/MASPs in a functional manner. PIC1 PA specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding to purified C1q.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | IALILEPICCQERAA |
Sequence(3-letter code) | H-Ile-Ala-Leu-Ile-Leu-Glu-Pro-Ile-Cys-Cys-Gln-Glu-Arg-Ala-Ala-OH |
Peptide Structure | 
|
Molecular Formula | C71H123N19O21S2 |
Molecular Weight | 1642.98 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： PIC1 PA;PIC1类似物多肽;1356469-36-7;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。