产品概述
Caspase 6 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
CASP6
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
839
P55212
产品应用
WB: 1:500-1:1000
Calculated MW: 33 kDa; Observed MW: 11,33 kDa
研究背景
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.
研究领域
Cell Biology
武汉恩玑生命科技有限公司
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