产品概述
p73 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IP,ChIP
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
TP73
TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
7161
O15350
产品应用
WB: 1:500-1:1000 IP: 1:20 ChIP: 1:20
Calculated MW: 70 kDa; Observed MW: 80,70 kDa
研究背景
p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.
研究领域
Cell Biology
武汉恩玑生命科技有限公司
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