产品概述
Fas Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,FC
Human
产品性能
Unconjugated
Unmodified
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Affinity Chromatography
免疫原
FAS
FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6
355
P25445
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 FC: 1:50-1:100
Calculated MW: 38 kDa; Observed MW: 48 kDa
研究背景
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
研究领域
Cell Biology
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