Product Name： Alloferon
CAS No.：347884-61-1
Synonyms：Alloferon 1；Antimicrobial peptide；丽蝇抗病毒肽1
Catalog No.：218P378
Brand：Typeptide Biotech（肽研生物）
Description：Alloferon是一类从细菌感染的果蝇分离得到的十三肽，具有抗肿瘤、抗病毒、抗炎症、免疫调控的多重生物活性，其发挥作用的机理类似免疫调节肽，通过激发机体自然杀伤细胞NK的细胞毒杀作用及促进干扰素INF-α来发挥其生物活性。2003年，Alloferon成功在俄罗斯上市，临床适应症为女性人乳头瘤病毒HPV感染。鉴于Alloferon的独特优势，如无细胞毒性、无免疫原性、无突变或致癌效应、无胚胎毒性、无生殖毒性，对于其衍生物的研究将为创造出更高效、安全的抗菌肽AMP、抗肿瘤多肽ACP。
Alloferon is a class of tridecapeptides isolated from bacteria-infected fruit flies, exhibiting multiple biological activities such as antitumor, antiviral, anti-inflammatory, and immunomodulatory effects. Its mechanism of action resembles that of immunomodulatory peptides, functioning by stimulating the cytotoxic activity of natural killer (NK) cells and promoting interferon INF-α to exert its biological effects. In 2003, Alloferon was successfully marketed in Russia, with clinical indications for female human papillomavirus (HPV) infection. Given Alloferon's unique advantages, such as non-cytotoxicity, non-immunogenicity, absence of mutagenic or carcinogenic effects, embryotoxicity, and reproductive toxicity, research on its derivatives will contribute to the development of more efficient and safer antimicrobial peptides (AMPs) and antitumor polypeptides (ACPs).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGVSGHGQHGVHG |
Sequence(3-letter code) | H-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C52H76N22O16 |
Molecular Weight | 1265.32 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： Alloferon;丽蝇抗病毒肽1;347884-61-1;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。