(Plonmarlimab)Biosimilar Reference Antibody-GS40553 新品

货号：GS40553

Plonmarlimab (also known as TJ003234 and the proposed international nonproprietary name Puna limab) is a human or humanized IgG1 kappa monoclonal antibody developed as a therapeutic agent. Its primary mechanism of action is the specific binding and neutralization of granulocyte-macrophage colony-stimulating factor (GM-CSF), a key cytokine. By inhibiting GM-CSF, plonmarlimab aims to disrupt the signaling pathway crucial for the activation, survival, and proliferation of myeloid lineage cells, particularly macrophages and neutrophils.