货号:GS40181
Devextinetug (also known as IXT‑M200) is a chimeric monoclonal antibody developed by InterveXion Therapeutics specifically as a pharmacotherapy for methamphetamine use disorder and overdose. It functions as a peripheral pharmacokinetic antagonist, designed to rapidly bind and sequester methamphetamine molecules in the bloodstream, thereby preventing the drug from reaching the brain and exerting its psychoactive effects. This approach offers a novel mechanism for treating acute intoxication and, with sustained administration, may aid in relapse prevention by blocking the reinforcing "high" of methamphetamine.
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