货号:GS40752
Tusamitamab is a humanized monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5, also known as CEA), a glycoprotein overexpressed in many epithelial cancers. It is developed as an antibody-drug conjugate (ADC), linked to a cytotoxic payload (e.g., a topoisomerase I inhibitor), to deliver targeted chemotherapy to CEACAM5-positive tumor cells. It is being evaluated for the treatment of advanced non-small cell lung cancer (NSCLC) and other CEACAM5-expressing solid tumors.
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