货号:GS40770
Utomilumab is a fully human monoclonal antibody agonist targeting CD137 (4-1BB), a co-stimulatory receptor on activated T cells and NK cells. It binds to CD137 to enhance T cell proliferation, cytokine production, and cytotoxic activity, thereby boosting anti-tumor immunity. It was investigated for the treatment of advanced solid tumors and hematologic malignancies, often in combination with other immunotherapies or targeted agents.
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