货号:GS40622
Romosozumab is a humanized monoclonal antibody targeting sclerostin (SOST). It binds to sclerostin, a protein produced by osteocytes that inhibits bone formation by blocking Wnt signaling. By neutralizing sclerostin, it promotes osteoblast activity and new bone formation. It is approved for the treatment of severe osteoporosis in postmenopausal women at high risk of fracture.
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