货号:GS40670
Sotigalimab is a humanized monoclonal antibody agonist targeting CD40, a co-stimulatory receptor on antigen-presenting cells (e.g., dendritic cells). By activating CD40 signaling, it enhances dendritic cell maturation, T cell priming, and anti-tumor immunity. It is being developed as an immunotherapeutic agent for solid tumors and melanoma, often in combination with chemotherapy or checkpoint inhibitors.
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