Monoclonal Anti-gC-HSV-2 (strain 333) Antibody, Mouse IgG1 (3A12) (MALS verified)
抗体来源(Source)
Monoclonal Anti-gC-HSV-2 (strain 333) Antibody, Mouse IgG1 (3A12) is a Mouse monoclonal antibody produced from a hybridoma created by fusing SP2/0 myeloma and Mouse B-lymphocytes.
克隆号(Clone)
3A12
种属(Species)
Mouse
亚型(Isotype)
Mouse IgG1 | Mouse Kappa
偶联(Conjugate)
Unconjugated
抗体类型(Antibody Type)
Hybridoma Monoclonal
种属反应性(Reactivity)
Virus
免疫原(Immunogen)
Recombinant HSV-2 (strain 333) Envelope Glycoprotein C (gC) derived from human 293 cells
特异性(Specificity)
This product is a specific antibody specifically reacts with Glycoprotein C/gC (HSV).
应用(Application)
Application | Recommended Usage |
ELISA | 0.2-100 ng/mL |
纯度(Purity)
95% as determined by SDS-PAGE.
90% as determined by SEC-MALS.
纯化(Purification)
Protein A purified / Protein G purified
制剂(Formulation)
Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
重构方法(Reconstitution)
Please refer to the Certificate of Analysis (CoA) for specific instructions.
For best performance, we strongly recommend following the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored in a lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景介绍
疱疹病毒感染在全球人群中广泛传播。单纯疱疹病毒(HSV)属于α-疱疹病毒亚科。感染人类的HSV主要有两种类型:HSV-1和HSV-2。HSV-2主要引起生殖器病变,而HSV-1则可导致口腔及生殖器感染。糖蛋白C(gC)是单纯疱疹病毒2型(HSV-2)包膜的结构成分,介导病毒与细胞表面硫酸乙酰肝素或硫酸软骨素的结合。此外,它还能通过抑制宿主补体级联反应的激活,在宿主免疫逃逸中发挥作用(根据相似性推测)。
关键字: gC (HSV) Antibody;Glycoprotein C;Anti-Glycoprotein C;百普赛斯;ACRO;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。