Product Name：Periplanetasin-4
CAS No.： 2206807-06-7
Synonyms：美洲蟑螂抗菌肽Periplanetasin-4
Catalog No.：220P384
Brand：Typeptide Biotech（肽研生物）
Description：Periplanetasin-4是一种可从美洲蟑螂 (Periplaneta americana) 中提取的抗菌肽，是由13个氨基酸组成的多肽。Periplanetasin-4 减少细胞圆化和凋亡 (apoptosis)。Periplanetasin-4 阻断 Clostridium difficile toxin A 诱导的 ROS 产生以及下游 p38 MAPK 和 p21 的激活。Periplanetasin-4显著增加Candida albicans ATCC 90028细胞中的线粒体钙水平，降低 DPH 荧光强度，并引发液泡功能障碍。Periplanetasin-4 显著改善小鼠肠道中毒素 A 诱导的黏膜损伤。Periplanetasin-4 可用于结肠炎的研究。
Periplanetasin-4 is an antimicrobial peptide extracted from American cockroaches (Periplaneta Americana), consisting of 13 amino acids. Periplanetasin-4 reduces cell rounding and apoptosis. Periplanetasin-4 blocks ROS production induced by Clostridium difficile toxin A and downstream activation of p38 MAPK and p21. Periplanetasin-4 significantly increases mitochondrial calcium levels in Candida albicans ATCC 90028 cells, reduces DPH fluorescence intensity, and induces vacuolar dysfunction. Periplanetasin-4 significantly improved mucosal damage induced by enterotoxin A in mice. Periplanetasin-4 can be used for research on colitis.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | LRHKVYGYCVLGP-NH2 |
Sequence(3-letter code) | H-Leu-Arg-His-Lys-Val-Tyr-Gly-Tyr-Cys-Val-Leu-Gly-Pro-NH2 |
Peptide Structure | 
|
Molecular Formula | C70H110N20O15S1 |
Molecular Weight | 1503.81 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： Periplanetasin-4;美洲蟑螂抗菌肽Periplanetasi;2206807-06-7;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。