ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

1,5-HEXADIYNE

Revision Date:2026-04-26Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 1,5-HEXADIYNE
  • CBnumber: CB8778536
  • CAS: 628-16-0
  • EINECS Number: 211-029-5
  • Synonyms: 1,5-hexadiyne,hexa-1,5-diyne

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
Hazard statements
H225 Highly Flammable liquid and vapour
H304 May be fatal if swallowed and enters airways
H315 Causes skin irritation
H319 Causes serious eye irritation
H336 May cause drowsiness or dizziness
H411 Toxic to aquatic life with long lasting effects

SECTION 3: Composition/information on ingredients

Substance

  • Product name: 1,5-HEXADIYNE
  • Synonyms: 1,5-hexadiyne,hexa-1,5-diyne
  • CAS: 628-16-0
  • EC number: 211-029-5
  • MF: C6H6
  • MW: 78.11

SECTION 4: First aid measures

First Aid Measures

General advice
Immediate medical attention is required. In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible).
General adviceImmediate medical attention is required. In case ofaccidentor unwellness, s
advice immediately (showdirections for use orsafety data sheet if possible).
Eye contactImmediately flushwith plenty of water. After initial flushing, remove any conta
continue flushingfor at least 15 minutes. Keepeyewide open while rinsing. I
persist, call a physician.
Skin ContactWash off immediately withplenty of water.
InhalationRemove to freshair Call aphysician If breathing isirregularor stopped, adm
respiration Avoiddirect contact with skin. Use barrier to givemouth-to-mouth
IngestionDo NOT induce vomiting.Rinse mouth. Drink plenty of water. If symptoms pe
physician.
Self-protection of the first aiderRemove all sources of ignition.
Eye contact
Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. If symptoms persist, call a physician.
Skin Contact
Wash off immediately with plenty of water.
Inhalation
Remove to fresh air Call a physician If breathing is irregular or stopped, administer artificial respiration Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation
Ingestion
Do NOT induce vomiting. Rinse mouth. Drink plenty of water. If symptoms persist, call a physician.
Self-protection of the first aider
Remove all sources of ignition.

Most important symptoms and effects, both acute and delayed

Symptoms
No information available.

Indication of any immediate medical attention and special treatment needed

Note to physicians
Treat symptomatically.

SECTION 5: Firefighting measures

Suitable Extinguishing Media

Suitable Extinguishing Media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
No information available.

Specific hazards arising from the chemical

Specific hazards arising from the chemical
No information available.
Hazardous combustion products
Carbon oxides.

Explosion data

Sensitivity to Mechanical Impact
No information available.
Sensitivity to Static Discharge
No information available.

Protective equipment and precautions for firefighters

Protective equipment and precautions for firefighters
As in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.

NFPA 704

3
4
0
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 4 Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal precautions
Remove all sources of ignition. Evacuate personnel to safe areas. Ensure adequate ventilation, especially in confined areas.

Environmental precautions

Environmental precautions
Prevent further leakage or spillage if safe to do so. Prevent product from entering drains.
See Section 12 for additional Ecological Information.

Methods and material for containment and cleaning up

Methods for containment
Prevent further leakage or spillage if safe to do so.
Methods for cleaning up
Pick up and transfer to properly labeled containers. Dam up. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust).

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling
Ensure adequate ventilation, especially in confined areas. Keep away from heat, sparks, flame and other sources of ignition (i.e., pilot lights, electric motors and static electricity).
Take precautionary measures against static discharges. Use spark-proof tools and explosion-proof equipment. All equipment used when handling the product must be grounded.

Conditions for safe storage, including any incompatibilities

Storage Conditions
Keep tightly closed in a dry and cool place. Keep in properly labeled containers. Store at room temperature.
Incompatible materials
None known based on information supplied.

SECTION 8: Exposure controls/personal protection

Control parameters

Exposure Guidelines
.
Other Information
Vacated limits revoked by the Court of Appeals decision in AFL-CIO v. OSHA, 965 F.2d 962 (11th Cir., 1992).
Column 1Column 2Column 3Column 4
Pentane 109-66-0TWA: 1000 ppmTWA: 1000 ppm
TWA: 2950 mg/m3 (vacated) TWA: 600 ppm (vacated) TWA: 1800 mg/m3 (vacated) STEL: 750 ppm (vacated) STEL: 2250 mg/m3		IDLH: 1500 ppm
Ceiling: 610 ppm 15 min
Ceiling: 1800 mg/m3 15 min
TWA: 120 ppm
TWA: 350 mg/m3
NIOSH IDLH Immediately Dangerous to Life or Health

Appropriate engineering controls

Engineering Controls
Showers
Eyewash stations
Ventilation systems

Individual protection measures, such as personal protective equipment

Eye/face protection
Tight sealing safety goggles.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Physical Stateliquid
  • AppearanceNo information available
  • OdorNo information available
  • pHNo information available
  • Melting point/freezing pointNo information available
  • Boiling point88 °C
  • Flash point-7 °C
  • Liquid Density0.805 g/mL
  • Evaporation rateNo information available
  • Upper flammability limitsNo information available
  • Lower flammability limitNo information available
  • Vapor pressureNo information available
  • Vapor densityNo information available
  • Specific gravityNo information available
  • Water solubilityImmiscible with water.
  • Solubility in other solventsNo information available
  • Partition coefficientNo information available
  • Autoignition temperatureNo information available
  • Decomposition temperatureNo information available
  • Kinematic viscosityNo information available
  • Explosive propertiesNo information available
  • Oxidizing propertiesNo information available
  • Density and/or relative density0,805 g/cm3
  • ColourColorless to Yellow

SECTION 10: Stability and reactivity

Reactivity

Not applicable

Chemical stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing.

Hazardous polymerization

No information available.

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

Strong oxidizing agents.

Hazardous Decomposition Products

Carbon oxides.

SECTION 11: Toxicological information

Information on likely routes of exposure

Inhalation
Classified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.

Information on toxicological effects

Symptoms
Classified based on available data. For more details, see section 2.

Delayed and immediate effects as well as chronic effects from short and long-term exposure

Chronic Toxicity
Classified based on available data. For more details, see section 2. Target Organ Effects Central nervous system, Eyes, Respiratory system, Skin.

Numerical measures of toxicity - Product Information

Unknown acute toxicity
50% of the mixture consists of ingredient(s) of unknown toxicity
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
2000 mg/kg
ATEmix (dermal)
3000 mg/kg
ATEmix (inhalation-dust/mist)
364 mg/l
ATEmix (inhalation-vapor)
364 mg/l

SECTION 12: Ecological information

Ecotoxicity

Toxic to aquatic life with long lasting effects
Chemical nameAlgae/aquatic plantsFishToxicity to
Microorganisms		Crustacea
Pentane 109-66-0-9.99: 96 h Lepomis macrochirus mg/L LC50 11.59: 96 h Pimephales promelas mg/L LC50 9.87: 96 h Oncorhynchus mykiss mg/L LC50-9.74: 48 h Daphnia magna mg/L EC50
109-66-0
50% of the mixture consists of components(s) of unknown hazards to the aquatic environment.

Pentane -

9.99: 96 h Lepomis - 9.74: 48 h Daphnia magna

Persistence and degradability

No information available.

Bioaccumulation

No information available.

Mobility

No information available.

Pentane

3.39 109-66-0

SECTION 13: Disposal considerations

Disposal of wastes

Disposal should be in accordance with applicable regional, national and local laws and regulations.

Contaminated packaging

Do not reuse container.

Other Information

Waste codes should be assigned by the user based on the application for which the product was used.

California Hazardous Waste Status

This product contains one or more substances that are listed with the State of California as a hazardous waste.
Chemical nameCalifornia Hazardous Waste Status
Pentane 109-66-0Toxic
Ignitable

Pentane

Toxic

SECTION 14: Transport information

DOT

UN/ID no
UN3295
Hazard Class
3
Packing Group
II
Proper shipping name
Hydrocarbons, liquid, n.o.s.
Description
UN3295, Hydrocarbons, liquid, n.o.s., 3, II
Emergency Response Guide Number
128

IMDG

UN/ID no
UN3295
Hazard Class
3
Packing Group
II
Proper shipping name
Hydrocarbons, liquid, n.o.s.
Description
UN3295, Hydrocarbons, liquid, n.o.s. (Pentane), 3, II, (-7°C c.c.), Marine pollutant
EmS-No
F-E, S-D

IATA

UN/ID no
UN3295
Hazard Class
3
Packing Group
II
Proper shipping name
Hydrocarbons, liquid, n.o.s.
Description
UN3295, Hydrocarbons, liquid, n.o.s., 3, II
ERG Code
3H

SECTION 15: Regulatory information

International Inventories

All of the components in the product are on the following Inventory lists
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) South Korea (KECL):
X - Listed
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
Chemical nameTSCADSLNDSLEINECSELINCSENCSIECSCKECLPICCSAICS
PentaneXX-X-XXXXX
1,5-HexadiyneX-XX---X--

US Federal Regulations

SARA 313

Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

SARA 311/312 Hazard Categories

Acute health hazard
Yes
Chronic Health Hazard
No
Fire hazard
Yes
Sudden release of pressure hazard
No
Reactive hazard
No

CWA (Clean Water Act)

This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).

US State Regulations

California Proposition 65

This product does not contain any Proposition 65 chemicals.

U.S. State Right-to-Know Regulations

Chemical nameNew JerseyMassachusettsPennsylvania
Pentane 109-66-0XXX

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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