Chemical Safety Data Sheet MSDS / SDS
2,3,4,5-TETRACHLOROPHENOL
Revision Date:2026-03-20Revision Number:1
Product identifier
- Product name: 2,3,4,5-TETRACHLOROPHENOL
- CBnumber: CB8263780
- CAS: 4901-51-3
- EINECS Number: 225-531-7
- Synonyms: 2,3,4,5-TECP;2.3.4.5-Tetrac
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Hazard statements
H410 Very toxic to aquatic life with long lasting effects
H335 May cause respiratory irritation
H318 Causes serious eye damage
H315 Causes skin irritation
H301 Toxic if swalloed
Substance
- Product name: 2,3,4,5-TETRACHLOROPHENOL
- Synonyms: 2,3,4,5-TECP;2.3.4.5-Tetrac
- CAS: 4901-51-3
- EC number: 225-531-7
- MF: C6H2Cl4O
- MW: 231.89
Description of first aid measures
General information
Immediately remove any clothing soiled by the product.
In case of irregular breathing or respiratory arrest provide artificial respiration.
In case of irregular breathing or respiratory arrest provide artificial respiration.
After inhalation
In case of unconsciousness place patient stably in side position for transportation.
After skin contact
Immediately wash with water and soap and rinse thoroughly.
After eye contact
Rinse opened eye for several minutes under running water. Then consult a doctor.
After swallowing
Do not induce vomiting; immediately call for medical help.
Information for doctor
Most important symptoms and effects, both acute and delayed
No further relevant information available.
Indication of any immediate medical attention and special treatment needed
No further relevant information available.
Extinguishing media
Suitable extinguishing agents
Use fire fighting measures that suit the environment.
A solid water stream may be inefficient.
A solid water stream may be inefficient.
Special hazards arising from the substance or mixture
No further relevant information available.
Advice for firefighters
Protective equipment
No special measures required.
NFPA 704
4
0
0
| HEALTH | 4 | Very short exposure could cause death or major residual injury (e.g. hydrogen cyanide, phosgene, methyl isocyanate, hydrofluoric acid) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Wear protective equipment. Keep unprotected persons away.
Environmental precautions
Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up
Use neutralizing agent.
Dispose contaminated material as waste according to section 13.
Ensure adequate ventilation.
Dispose contaminated material as waste according to section 13.
Ensure adequate ventilation.
Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
Protective Action Criteria for Chemicals
PAC-1
Substance is not listed.
PAC-2
Substance is not listed.
PAC-3
Substance is not listed.
Handling
Precautions for safe handling
Thorough dedusting.
Information about protection against explosions and fires
No special measures required.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed.
Store in accordance with information listed on the product insert.
Store in accordance with information listed on the product insert.
Storage
Store in accordance with information listed on the product insert.
Requirements to be met by storerooms and receptacles
No special requirements.
Information about storage in one common storage facility
Not required.
Further information about storage conditions
Keep receptacle tightly sealed.
Specific end use(s)
No further relevant information available.
Additional information about design of technical systems
No further data; see section 7.
Control parameters
Components with limit values that require monitoring at the workplace
Not required.
Additional information
The lists that were valid during the creation were used as basis.
Exposure controls
Personal protective equipment
General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the skin.
Avoid contact with the eyes and skin.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the skin.
Avoid contact with the eyes and skin.
Breathing equipment
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.
Protection of hands
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.
Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
Eye protection
Tightly sealed goggles
Information on basic physicochemical properties
- Water solubility166mg/L(25 ºC)
- Relative Density1.7544 (rough estimate)
- Density1.7544 (rough estimate)
- Vapor PressureNot applicable.
- Explosion limitsLower: Not determined.
Upper: Not determined. - Danger of explosionProduct does not present an explosion hazard.
- Ignition temperatureNot determined.
- Decomposition temperatureNot determined.
- Flammability (solid,gas)Product is not flammable.
- Flash point4 °C
- Boiling point/Boiling range331.59°C (rough estimate)
- Melting point/Melting rangeUndetermined.
- pHNot applicable.
- Odor ThresholdNot determined.
- Molecular Weight231.9 g/mol
- Structural FormulaC6H2Cl4O
- OdorCharacteristic
- ColorNot determined.
- Physical StateSolid
- Other informationNo information available
- SOLUBILITYDMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml;
Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml - KinematicNot applicable.
- DynamicNot applicable.
- Partition coefficient (n-octanol/water)Not determined.
- WaterNot determined.
- Solubility in / Miscibility withDMF: 30 mg/ml,DMSO: 15 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
- Evaporation RateNot applicable.
- Vapor DensityNot applicable.
Reactivity
No further relevant information available.
Chemical stability
Thermal decomposition / conditions to be avoided
No decomposition if used according to specifications.
Possibility of hazardous reactions
No dangerous reactions known.
Conditions to avoid
No further relevant information available.
Incompatible materials
acid anhydrides, oxidizing agents
Hazardous decomposition products
carbon oxides, hydrogen chloride
Information on toxicological effects
Acute toxicity
Primary irritant effect
on the skin
Irritant to skin and mucous membranes.
on the eye
Strong irritant with the danger of severe eye injury.
Sensitization
No sensitizing effects known.
Additional toxicological information
Carcinogenic categories
IARC (International Agency for Research on Cancer)
Substance is not listed.
NTP (National Toxicology Program)
Substance is not listed.
OSHA-Ca (Occupational Safety & Health Administration)
Substance is not listed.
Toxicity
Aquatic toxicity
No further relevant information available.
Persistence and degradability
No further relevant information available.
Behavior in environmental systems
Bioaccumulative potential
No further relevant information available.
Mobility in soil
No further relevant information available.
Additional ecological information
General notes
Water hazard class 3 (Self-assessment) extremely hazardous for water
Do not allow product to reach ground water, water course or sewage system, even in small quantities.
Must not reach bodies of water or drainage ditch undiluted or unneutralized.
Danger to drinking water if even extremely small quantities leak into the ground.
Do not allow product to reach ground water, water course or sewage system, even in small quantities.
Must not reach bodies of water or drainage ditch undiluted or unneutralized.
Danger to drinking water if even extremely small quantities leak into the ground.
Results of PBT and vPvB assessment
PBT
Not applicable.
vPvB
Not applicable.
PBT:
Not applicable.
vPvB:
Not applicable.
Other adverse effects
No further relevant information available.
Waste treatment methods
Recommendation
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings
Recommendation
Disposal must be made according to official regulations.
UN-Number
DOT, IMDG, IATA UN3288
UN proper shipping name
DOT, IATA Toxic solid, inorganic, n.o.s. (2,3,4,5-
Tetrachlorophenol)
IMDG TOXIC SOLID, INORGANIC, N.O.S. (2,3,4,5-
Tetrachlorophenol)
Tetrachlorophenol)
IMDG TOXIC SOLID, INORGANIC, N.O.S. (2,3,4,5-
Tetrachlorophenol)
Transport hazard class(es)
DOTClass: 6.1 Toxic substances
Label: 6.1
IMDG, IATA
Label: 6.1
Class: 6.1 Toxic substances
Label: 6.1
Label: 6.1
Packing group
DOT, IMDG, IATA III
Environmental hazards
Environmentally hazardous substance, solid
Special precautions for user
Warning: Toxic substances
Hazard identification number (Kemler code)
60
EMS Number
F-A,S-A
Stowage Category
A
Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code
Not applicable.
Transport/Additional information
DOT:
Quantity limitations
On passenger aircraft/rail: 100 kg
On cargo aircraft only: 200 kg
On cargo aircraft only: 200 kg
IMDG:
Limited quantities (LQ)
5 kg
Excepted quantities (EQ)
Code: E1
Maximum net quantity per inner packaging: 30 g
Maximum net quantity per outer packaging: 1000 g
Maximum net quantity per inner packaging: 30 g
Maximum net quantity per outer packaging: 1000 g
IATA:
Remarks
When sold in quantities of less than or equal to 1 mL, or 1 g, with an Excepted Quantity Code of
E1, E2, E4, or E5, this item meets the De Minimis
Quantities exemption, per IATA 2.6.10.
Therefore packaging does not have to be labeled as
Dangerous Goods/Excepted Quantity.
E1, E2, E4, or E5, this item meets the De Minimis
Quantities exemption, per IATA 2.6.10.
Therefore packaging does not have to be labeled as
Dangerous Goods/Excepted Quantity.
UN "Model Regulation"
UN 3288 TOXIC SOLID, INORGANIC, N.O.S.
(2,3,4,5-TETRACHLOROPHENOL), 6.1, III,
ENVIRONMENTALLY HAZARDOUS
(2,3,4,5-TETRACHLOROPHENOL), 6.1, III,
ENVIRONMENTALLY HAZARDOUS
Safety, health and environmental regulations/legislation specific for the substance or mixture
No further relevant information available.
Sara
| Section 355 (extremely hazardous substances): | Substance is not listed. |
| Section 313 (Specific toxic chemical listings): | Substance is not listed. |
| TSCA (Toxic Substances Control Act): | Substance is not listed. |
| Hazardous Air Pollutants: | Substance is not listed. |
Proposition 65
| Chemicals known to cause cancer: | Substance is not listed. |
| Chemicals known to cause reproductive toxicity for females: | Substance is not listed. |
| Chemicals known to cause reproductive toxicity for males: | Substance is not listed. |
| Chemicals known to cause developmental toxicity: | Substance is not listed. |
Chemicals known to cause cancer
Substance is not listed.
Chemicals known to cause reproductive toxicity for females
Substance is not listed.
Chemicals known to cause reproductive toxicity for males
Substance is not listed.
Chemicals known to cause developmental toxicity
Substance is not listed.
Carcinogenic categories
| EPA (Environmental Protection Agency): | Substance is not listed. |
TLV (Threshold Limit Value)
Substance is not listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
Substance is not listed.
Chemical safety assessment
A Chemical Safety Assessment has not been carried out.
Abbreviations and acronyms
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety & Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Acute Toxicity - Oral 3: Acute toxicity – Category 3
Skin Irritation 2: Skin corrosion/irritation – Category 2
Eye Damage 1: Serious eye damage/eye irritation – Category 1
Specific Target Organ Toxicity - Single Exposure 3: Specific target organ toxicity (single exposure) – Category 3
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety & Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Acute Toxicity - Oral 3: Acute toxicity – Category 3
Skin Irritation 2: Skin corrosion/irritation – Category 2
Eye Damage 1: Serious eye damage/eye irritation – Category 1
Specific Target Organ Toxicity - Single Exposure 3: Specific target organ toxicity (single exposure) – Category 3
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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