Chemical Safety Data Sheet MSDS / SDS

1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: 1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • CBnumber: CB1481125
  • CAS: 86288-11-1
  • EINECS Number: 200-578-6
  • Synonyms: ARACHIDONOYL PAF C-16;1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-PC

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P201 Obtain special instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Hazard statements
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H331 Toxic if inhaled
H336 May cause drowsiness or dizziness
H351 Suspected of causing cancer
H372 Causes damage to organs through prolonged or repeated exposure

SECTION 3: Composition/information on ingredients

Substance

  • Product name: 1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • Synonyms: ARACHIDONOYL PAF C-16;1-O-hexadecyl-2-Arachidonoyl-sn-glycero-3-PC
  • CAS: 86288-11-1
  • EC number: 200-578-6
  • MF: C44H82NO7P
  • MW: 768.1

SECTION 4: First aid measures

General advice

First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.

In case of eye contact

After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.

If swallowed

After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

Not combustible. Ambient fire may liberate hazardous vapours.

Hazardous combustion products

Carbon oxides Hydrogen chloride gas

Specific extinguishing methods

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

NFPA 704

2
3
0
HEALTH 2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE 3 Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material . Dispose of properly. Clean up affected area.

SECTION 7: Handling and storage

Handling

Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Avoidance of contact
Strong oxidizing agents Strong bases Magnesium Sodium/sodium oxides Lithium various plastics

Storage

Further information on storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Storage class
6.1D, Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Recommended storage temperature
-20 °C

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Engineering measures

No data available

Personal protective equipment

Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses
Skin and body protection
protective clothing
Hand protection
Remarks
required
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Flash point14 °C
  • Physical statePale yellow waxy solid.
  • Appearanceliquid
  • Colorcolorless
  • Odorsweet
  • Odor ThresholdNo data available
  • pHNo data available
  • Melting point/ range-63.5 °C (1,013 hPa)
  • Boiling point/boiling range61.2 °C (1,013 hPa)
    Flash point : Method: DIN 51755 Part 1 does not flash Not applicable
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Flammability (liquids)The product is not flammable.
  • Burning rateNo data available
  • Self-ignition> 600 °C 1,013 hPa
    Method: DIN 51794 Not applicable
  • Upper explosion limit / Upper flammability limitNot applicable
  • Lower explosion limit / Lower flammability limitNot applicable
  • Vapor pressure210 hPa (20 °C)
  • Relative vapor density4.12
  • Relative densityNo data available
  • Density1.49 g/cm3
  • Water solubility8.7 g/l (23 °C)
    Method: OECD Test Guideline 105
  • Partition coefficient: n-octanol/waterlog Pow: 1.97 (25 °C)
    Method: (experimental) (ECHA) Bioaccumulation is not expected.
  • Autoignition temperatureNot applicable
    Decomposition tempera-: Distillable in an undecomposed state at normal presture sure.
  • Viscosity, dynamicNo data available
  • Viscosity, kinematicNo data available
  • Flow timeNo data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesnone
  • Surface tension27.1 mN/m, 20.0 °C
  • Particle characteristics Particle sizeNo data available
  • Solubility in other solventsmiscible organic solvent: (20 °C)

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Contains the following stabilizer(s):

ethanol (0.5 %)

Possibility of hazardous reactions

No data available

Conditions to avoid

no information available

Incompatible materials

Strong oxidizing agents Strong bases Magnesium Sodium/sodium oxides Lithium various plastics

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture Acute toxicity
Acute toxicity estimate Oral - 917.17 mg/kg (Calculation method)
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Acute toxicity estimate Inhalation - 4 h - 3.13 mg/l - vapor(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Dermal: No data available
Skin corrosion/irritation
Remarks: Mixture causes skin irritation.
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Evidence of a carcinogenic effect.
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Mixture may cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Mixture causes damage to organs through prolonged or repeated exposure.
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.
Handle in accordance with good industrial hygiene and safety practice.
Components Chloroform
Acute toxicity
LD50 Oral - Rat - male - 908 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Rat - 6 h - 9.17 mg/l - vapor
Acute toxicity estimate Inhalation - Expert judgment - 4 h - 3.1 mg/l - va- por
Dermal: No data available
Skin corrosion/irritation
Skin - Rabbit
Result: Irritating to skin. - 24 h
Remarks: (ECHA)
Remarks: Drying-out effect resulting in rough and chapped skin.
Skin - Rabbit
Result: slight irritation
Remarks: (IUCLID)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irritating to eyes.
Remarks: (ECHA)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Respiratory or skin sensitization
Maximization Test - Guinea pig
Result: negative (Regulation (EC) No. 440/2008, Annex, B.6)
Germ cell mutagenicity
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Result: negative
Remarks: (ECHA)
Test Type: unscheduled DNA synthesis assay
Test system: Liver
Result: negative
Remarks: (ECHA)
Method: OECD Test Guideline 474
Species: Rat - male and female - Red blood cells (erythrocytes)
Result: negative
Method: OECD Test Guideline 486
Species: Rat - male - Liver cells
Result: negative
Species: Mouse - female
Result: negative
Remarks: (ECHA)
Carcinogenicity
Suspected of causing cancer.
Reproductive toxicity
Suspected of damaging the unborn child.
Specific target organ toxicity - single exposure
May cause drowsiness or dizziness.
Specific target organ toxicity - repeated exposure
Oral - Causes damage to organs through prolonged or repeated exposure.
- Liver, Kidney
Aspiration hazard
Classified based on available data. For more details, see section 2

SECTION 12: Ecological information

Ecotoxicity

Components:

Chloroform:

Toxicity to daphnia and other aquatic invertebrates
EC50 (Crassostrea gigas): 152.5 mg/l Exposure time: 48 h Test Type: static test Analytical monitoring: yes Remarks: (ECHA)
Toxicity to algae/aquatic plants
ErC50 (Chlamydomonas reinhardtii (green algae)): 13.3 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Remarks: (ECHA)
Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity)
NOEC (Daphnia magna (Water flea)): 6.3 mg/l End point: reproduction rate Exposure time: 21 d Test Type: semi-static test Analytical monitoring: yes Remarks: (ECHA)

Ecotoxicology Assessment

Chronic aquatic toxicity
This product has no known ecotoxicological effects.

Persistence and degradability

Components:

Chloroform:

Biodegradability
Remarks: No data available

Bioaccumulative potential

Components:

Chloroform:

Bioaccumulation
Remarks: No data available

Mobility in soil

Components:

Chloroform:

Distribution among environmental compartments
Adsorption/Soil Koc: 52.5, log Koc: 1.72 Method: (experimental) Remarks: Mobile in soils

Other adverse effects

Components:

Chloroform:

Results of PBT and vPvB assessment
Substance does not meet the criteria for PBT or vPvB according to Regulation (EC) No 1907/2006, Annex XIII.

SECTION 13: Disposal considerations

Disposal methods

Waste from residues
Offer surplus and non-recyclable solutions to a licensed disposal company.

SECTION 14: Transport information

International Regulations

IATA-DGR

UN/ID No. : UN 1888
Proper shipping name : Chloroform solution
Class : 6.1
Packing group : III
Labels : Division 6.1 - Toxic substances
Packing instruction (cargo aircraft) : 680
Packing instruction (passenger aircraft) : 680

IMDG-Code

UN number : UN 1888
Proper shipping name : CHLOROFORM SOLUTION
Class : 6.1
Packing group : III
Labels : 6.1
EmS Code : F-A, S-A
Marine pollutant : no

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

Not applicable for product as supplied.
National regulation GB 6944/12268
UN number : UN 1888
Proper shipping name : CHLOROFORM
Class : 6.1
Packing group : III
Labels : 6.1

Special precautions for user

The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.

SECTION 15: Regulatory information

National regulatory information

Law on the Prevention and Control of Occupational Diseases

Regulations on Safety Management of Hazardous Chemicals

Catalogue of Hazardous Chemicals

Hazardous Chemicals for Priority Management

Not applicable under SAWS

Catalogue of Specially Controlled Hazardous

Listed Chemicals

List of Explosive Precursors

Not listed

Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals

China Severely Restricted Toxic Chemicals for Import and Export

Not applicable

Regulation on the Administration of Precursor Chemicals

Catalogue and Classification of Precursor Chemicals

Listed

Regulations on the Administration of Controlled Chemicals

List of Controlled Chemicals

Not listed

Regulations of Ozone Depleting Substances Management

List of Controlled Ozone Depleting Substances

Not listed

List of Controlled Ozone Depleting Substances Import and Export

Not listed

Environmental Protection Law

List of Priority Controlled Chemicals

Listed

List of Key Controlled New Pollutants

Listed

SECTION 16: Other information

Full text of other abbreviations

ACGIH
USA. ACGIH Threshold Limit Values (TLV)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
GBZ 2.1-2007 / PC-TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - time weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 - ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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