Chemical Safety Data Sheet MSDS / SDS
ACETONE-D6
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: ACETONE-D6
- CBnumber: CB7693142
- CAS: 666-52-4
- EINECS Number: 211-563-9
- Synonyms: (CD3)2CO;ACETONE-D6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P242 Use only non-sparking tools.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P240 Ground/bond container and receiving equipment.
P233 Keep container tightly closed.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H336 May cause drowsiness or dizziness
H319 Causes serious eye irritation
H225 Highly Flammable liquid and vapour
Substance
- Product name: ACETONE-D6
- Synonyms: (CD3)2CO;ACETONE-D6
- CAS: 666-52-4
- EC number: 211-563-9
- MF: C3D6O
- MW: 64.12
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaCarbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
1
3
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Store under inert gas. Hygroscopic.
Storage class
Store under inert gas. Hygroscopic.
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['(2H6)acetone', '666-52-4', 'PC-TWA', '300 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] | ['', '', 'PC-STEL', '450 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] |
|---|
| ['Component', 'CAS-No.', 'Parameters', 'Value', 'Biological\nspecimen', 'Basis'] | ['', '666-52-4', 'Acetone', '50 mg/l', 'Urine', 'China. Biological\nOccupational\nExposure Indices'] | ['', 'Remarks', 'End of shift', None, None, None] |
|---|
8.2 Exposure controls
Appropriate engineering controlsChange contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 480 min
Material tested:Butoject® (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Latex gloves
Minimum layer thickness: 0.6 mm
Break through time: 10 min
Material tested:Lapren® (KCL 706 / Aldrich Z677558, Size M)
Body Protection
Internet: www.kcl.de).
Full contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 480 min
Material tested:Butoject® (KCL 898)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Latex gloves
Minimum layer thickness: 0.6 mm
Break through time: 10 min
Material tested:Lapren® (KCL 706 / Aldrich Z677558, Size M)
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) ColorColorless
- c) OdorNo data available
- d) Melting point/freezing pointMelting point/range: -93.8 °C - lit.
- e) Initial boiling point and boiling range55.5 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 13.2 %(V)
Lower explosion limit: 2.15 %(V) - h) Flash point-19 °C - closed cup
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureNo data available
- k) pH5-6 (365g/l, H2O)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubilitySoluble in water.
- n) Partition coefficient n-octanol/waterNo data available
- o) Vapor pressure245 hPa at 20 °C
- p) Density0.872 g/cm3 at 25 °C - lit.
- Relative density0.872 g/mL at 25 °C(lit.)
- q) Relative vapor density2 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
9.2 Other safety information
Relative vapor density2.21 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Risk of explosion with: chromosulfuric acid chromyl chloride ethanolamine
Fluorine
Strong oxidizing agents strong reducing agents
Nitric acid chromium(VI) oxide nonmetallic oxyhalides halogen-halogen compounds
Chloroform nitrating acid nitrosyl compounds hydrogen peroxide halogen oxides organic nitro compounds peroxi compounds
Risk of ignition or formation of inflammable gases or vapours with:
Exothermic reaction with:
Bromine
Alkali metals alkali hydroxides
Halogenated hydrocarbon
Sulfur dichloride phosphorous oxichloride
Fluorine
Strong oxidizing agents strong reducing agents
Nitric acid chromium(VI) oxide nonmetallic oxyhalides halogen-halogen compounds
Chloroform nitrating acid nitrosyl compounds hydrogen peroxide halogen oxides organic nitro compounds peroxi compounds
Risk of ignition or formation of inflammable gases or vapours with:
Exothermic reaction with:
Bromine
Alkali metals alkali hydroxides
Halogenated hydrocarbon
Sulfur dichloride phosphorous oxichloride
10.3 Conditions to avoid
Avoid moisture.
Warming.
Warming.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - 5,800 mg/kg
Remarks: (ECHA)
The value is given in analogy to the following substances: acetone
Symptoms: Stomach/intestinal disorders, Risk of aspiration upon vomiting., Pulmonary failure possible after aspiration of vomit.
LC50 Inhalation - Rat - 4 h - 76 mg/l - vapor
Remarks: Unconsciousness
Drowsiness
Dizziness (External MSDS)
The value is given in analogy to the following substances: acetone
LD50 Dermal - Rabbit - 20,000 mg/kg
Remarks: (IUCLID)
The value is given in analogy to the following substances: acetone
Skin corrosion/irritation
Remarks: (ECHA)
The value is given in analogy to the following substances: acetone
Symptoms: Stomach/intestinal disorders, Risk of aspiration upon vomiting., Pulmonary failure possible after aspiration of vomit.
LC50 Inhalation - Rat - 4 h - 76 mg/l - vapor
Remarks: Unconsciousness
Drowsiness
Dizziness (External MSDS)
The value is given in analogy to the following substances: acetone
LD50 Dermal - Rabbit - 20,000 mg/kg
Remarks: (IUCLID)
The value is given in analogy to the following substances: acetone
Skin - Rabbit
Result: Mild skin irritation - 24 h (Draize Test)
Remarks: (RTECS)
The value is given in analogy to the following substances: acetone
Serious eye damage/eye irritation
Result: Mild skin irritation - 24 h (Draize Test)
Remarks: (RTECS)
The value is given in analogy to the following substances: acetone
Eyes - Rabbit
Result: Eye irritation - 24 h (Draize Test)
Remarks: (RTECS)
The value is given in analogy to the following substances: acetone
Respiratory or skin sensitization
Result: Eye irritation - 24 h (Draize Test)
Remarks: (RTECS)
The value is given in analogy to the following substances: acetone
Maximization Test - Guinea pig
Result: negative
Remarks: (ECHA)
The value is given in analogy to the following substances: acetone
Chronic exposure may cause dermatitis.
Germ cell mutagenicity
Result: negative
Remarks: (ECHA)
The value is given in analogy to the following substances: acetone
Chronic exposure may cause dermatitis.
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Remarks: The value is given in analogy to the following substances: acetoneTest Type:
Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: The value is given in analogy to the following substances: acetoneTest Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: The value is given in analogy to the following substances: acetoneCarcinogenicity
No data available
Reproductive toxicity
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Remarks: The value is given in analogy to the following substances: acetoneTest Type:
Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: The value is given in analogy to the following substances: acetoneTest Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: The value is given in analogy to the following substances: acetoneCarcinogenicity
No data available
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause drowsiness or dizziness. - Narcotic effects
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
The value is given in analogy to the following substances: acetone
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
The value is given in analogy to the following substances: acetone
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After absorption:
Headache
Salivation
Nausea
Vomiting
Dizziness narcosis
Coma
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Kidney - Irregularities - Based on Human Evidence
Skin - Dermatitis - Based on Human Evidence
After absorption:
Headache
Salivation
Nausea
Vomiting
Dizziness narcosis
Coma
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Kidney - Irregularities - Based on Human Evidence
Skin - Dermatitis - Based on Human Evidence
12.1 Toxicity
Toxicity to fish flow-through test LC50 - Pimephales promelas (fathead minnow) - 6,210 mg/l - 96 h (OECD Test Guideline 203)
Remarks: The value is given in analogy to the following substances: acetone
Toxicity to daphnia static test LC50 - Daphnia pulex (Water flea) - 8,800 mg/l - 48 h and other aquatic Remarks: (ECHA) invertebrates The value is given in analogy to the following substances: acetone
Toxicity to algae static test NOEC - M.aeruginosa - 530 mg/l - 8 d (DIN 38412)
Remarks: (maximum permissible toxic concentration) (IUCLID)
The value is given in analogy to the following substances: acetone
Toxicity to bacteria static test EC50 - activated sludge - 61.15 mg/l - 30 min (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances: acetone
Toxicity to daphnia flow-through test NOEC - Daphnia magna (Water flea) - 2,212 mg/l and other aquatic - 28 d invertebrates(Chronic Remarks: (ECHA) toxicity) The value is given in analogy to the following substances: acetone
Remarks: The value is given in analogy to the following substances: acetone
Toxicity to daphnia static test LC50 - Daphnia pulex (Water flea) - 8,800 mg/l - 48 h and other aquatic Remarks: (ECHA) invertebrates The value is given in analogy to the following substances: acetone
Toxicity to algae static test NOEC - M.aeruginosa - 530 mg/l - 8 d (DIN 38412)
Remarks: (maximum permissible toxic concentration) (IUCLID)
The value is given in analogy to the following substances: acetone
Toxicity to bacteria static test EC50 - activated sludge - 61.15 mg/l - 30 min (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances: acetone
Toxicity to daphnia flow-through test NOEC - Daphnia magna (Water flea) - 2,212 mg/l and other aquatic - 28 d invertebrates(Chronic Remarks: (ECHA) toxicity) The value is given in analogy to the following substances: acetone
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 91 % - Readily biodegradable.
(OECD Test Guideline 301B)
Remarks: The value is given in analogy to the following substances: acetone
Result: 91 % - Readily biodegradable.
(OECD Test Guideline 301B)
Remarks: The value is given in analogy to the following substances: acetone
12.3 Bioaccumulative potential
Does not bioaccumulate.
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 1090
IMDG: 1090
IATA-DGR: 1090
IMDG: 1090
IATA-DGR: 1090
14.2 UN proper shipping name
ADR/RID: ACETONE
IMDG: ACETONE
IATA-DGR: Acetone
IMDG: ACETONE
IATA-DGR: Acetone
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.