ChemicalBook
Chemical Safety Data Sheet MSDS / SDS

Aconitine

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Aconitine
  • CBnumber: CB1343300
  • CAS: 302-27-2
  • EINECS Number: 206-121-7
  • Synonyms: ACONITIN;Acotinine

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
No data available
Hazard statements
No data available

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Aconitine
  • Synonyms: ACONITIN;Acotinine
  • CAS: 302-27-2
  • EC number: 206-121-7
  • MF: C34H47NO11
  • MW: 645.74

SECTION 4: First aid measures

First Aid Measures

General advice
Immediate medical attention is required.
Eye contact
Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. Call a physician immediately.
Skin Contact
Immediate medical attention is required. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation
Immediate medical attention is required Remove to fresh air If not breathing, give artificial respiration Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation
Ingestion
Do NOT induce vomiting. Call a physician or poison control center immediately. Never give anything by mouth to an unconscious person. Drink plenty of water.
Self-protection of the first aider
Use personal protective equipment as required. Avoid contact with skin, eyes or clothing.
Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination.

Most important symptoms and effects, both acute and delayed

Symptoms
No information available.

Indication of any immediate medical attention and special treatment needed

Note to physicians
Treat symptomatically.

SECTION 5: Firefighting measures

Suitable Extinguishing Media

Suitable Extinguishing Media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
No information available.

Specific hazards arising from the chemical

Specific hazards arising from the chemical
No information available.
Hazardous combustion products
Carbon oxides. Nitrogen oxides (NOx).

Explosion data

Sensitivity to Mechanical Impact
No information available.
Sensitivity to Static Discharge
No information available.

Protective equipment and precautions for firefighters

Protective equipment and precautions Wear self-contained breathing apparatus and protective suit.
for firefighters

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Personal precautions
Use personal protective equipment as required. Keep people away from and upwind of spill/leak.

Environmental precautions

Environmental precautions
Prevent further leakage or spillage if safe to do so. Prevent product from entering drains.
See Section 12 for additional Ecological Information.

Methods and material for containment and cleaning up

Methods for containment
Prevent further leakage or spillage if safe to do so. Cover powder spill with plastic sheet or tarp to minimize spreading. Dike far ahead of liquid spill for later disposal.
Methods for cleaning up
Use personal protective equipment as required. Take up mechanically, placing in appropriate containers for disposal. Clean contaminated surface thoroughly. Cover powde spill with plastic sheet or tarp to minimize spreading and keep powder dry. Avoid creating dust.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on safe handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required.
Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray.
Do not eat, drink or smoke when using this product. Noxious vapor/odor. Ensure adequate ventilation, especially in confined areas.

Conditions for safe storage, including any incompatibilities

Storage Conditions
Keep container tightly closed in a dry and well-ventilated place. Keep out of the reach of children. Store at 4 °C.
Incompatible materials
None known based on information supplied.

SECTION 8: Exposure controls/personal protection

Control parameters

Exposure Guidelines
This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.

Appropriate engineering controls

Engineering Controls
Ensure adequate ventilation, especially in confined areas

Individual protection measures, such as personal protective equipment

Eye/face protection
Tight sealing safety goggles.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended. Avoid contact with skin, eyes or clothing. Wash hands thoroughly after handling. Keep away from food, drink and animal feeding stuffs.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Physical StateSolid
  • Appearancepowder
  • Odorcharacteristic
  • pHNo information available
  • Melting point/freezing point204 °C
  • Boiling point717.21 °C
  • Flash point387.56 °C
  • Liquid Density1.38 g/cm3
  • Evaporation rateNo information available
  • Upper flammability limitsNo information available
  • Lower flammability limitNo information available
  • Vapor pressure0 mmHg
  • Vapor densityNo information available
  • Specific gravityNo information available
  • Water solubilitySoluble in ethanol. Sparingly soluble in water
  • Solubility in other solventsNo information available
  • Partition coefficient2.01
  • Autoignition temperatureNo information available
  • Decomposition temperatureNo information available
  • Kinematic viscosityNo information available
  • Explosive propertiesNo information available
  • Oxidizing propertiesNo information available
  • Density and/or relative density1.2181 (rough estimate)
  • SolubilitySoluble in ethanol;
  • ColourWhite

SECTION 10: Stability and reactivity

Reactivity

Not applicable

Chemical stability

Stable under recommended storage conditions.

Possibility of Hazardous Reactions

None under normal processing.

Hazardous polymerization

No information available.

Conditions to avoid

Extremes of temperature and direct sunlight.

Incompatible materials

Strong oxidizing agents.

Hazardous Decomposition Products

Carbon oxides. Nitrogen oxides (NOx).

SECTION 11: Toxicological information

Information on likely routes of exposure

Inhalation
Classified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.

Information on toxicological effects

Symptoms
Classified based on available data. For more details, see section 2.

Delayed and immediate effects as well as chronic effects from short and long-term exposure

Chronic Toxicity
Prolonged or repeated exposure increases the risk. Possible risk of irreversible effects.

Numerical measures of toxicity - Product Information

Unknown acute toxicity
Classified based on available data. For more details, see section 2
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
0 mg/kg
ATEmix (inhalation-dust/mist)
0 mg/l

SECTION 12: Ecological information

Ecotoxicity

May cause long lasting harmful effects to aquatic life
100% of the mixture consists of components(s) of unknown hazards to the aquatic environment.

Persistence and degradability

No information available.

Bioaccumulation

No information available.

Mobility

No information available.

SECTION 13: Disposal considerations

Disposal of wastes

Disposal should be in accordance with applicable regional, national and local laws and regulations.

Contaminated packaging

Do not reuse container.

Other Information

Waste codes should be assigned by the user based on the application for which the product was used.

SECTION 14: Transport information

DOT

UN/ID no
UN1544
Hazard Class
6.1
Packing Group
I
Proper shipping name
Alkaloids, solid, n.o.s.
Description
UN1544, Alkaloids, solid, n.o.s. (Aconitine), 6.1, I
Emergency Response Guide Number
151

IMDG

UN/ID no
UN1544
Hazard Class
6.1
Packing Group
I
Proper shipping name
Alkaloids, solid, n.o.s.
Description
UN1544, Alkaloids, solid, n.o.s. (Aconitine), 6.1, I
Special Provisions
43, 274
EmS-No
F-A, S-A

IATA

UN/ID no
UN1544
Hazard Class
6.1
Packing Group
I
Proper shipping name
Alkaloid salts, solid, n.o.s.
Description
UN1544, Alkaloid salts, solid, n.o.s. (Aconitine), 6.1, I
ERG Code
6L

SECTION 15: Regulatory information

International Inventories

All of the components in the product are on the following Inventory lists
Europe (EINECS/ELINCS/NLP)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
Chemical nameTSCADSLNDSLEINECSELINCSENCSIECSCKECLPICCSAICS
Aconitine---X------

US Federal Regulations

SARA 313

Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

SARA 311/312 Hazard Categories

Acute health hazard
Yes
Chronic Health Hazard
Yes
Fire hazard
No
Sudden release of pressure hazard
No
Reactive hazard
No

CWA (Clean Water Act)

This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).

US State Regulations

California Proposition 65

This product does not contain any Proposition 65 chemicals.

U.S. State Right-to-Know Regulations

This product does not contain any substances regulated by state right-to-know regulations

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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