Chemical Safety Data Sheet MSDS / SDS
Acrylamide
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Acrylamide
- CBnumber: CB4690458
- CAS: 79-06-1
- EINECS Number: 201-173-7
- Synonyms: ACRYLAMIDE;Acrylamid
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P202 Do not handle until all safety precautions have been read and understood.
Hazard statements
H301 Toxic if swalloed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H340 May cause genetic defects
H350 May cause cancer
H372 Causes damage to organs through prolonged or repeated exposure
Substance
- Product name: Acrylamide
- Synonyms: ACRYLAMIDE;Acrylamid
- CAS: 79-06-1
- EC number: 201-173-7
- MF: C3H5NO
- MW: 71.08
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
If swallowed: give water to drink (two glasses at most). Seek medical advice immediately.
In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.
In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Nitrogen oxides (NOx)
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
2
2
2
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 2 | Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area.
Avoid generation of dusts.
Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Light sensitive. Store under inert gas.
Storage class
Light sensitive. Store under inert gas.
Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['acrylamide', '79-06-1', 'PC-TWA', '0.3 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] | ['', 'Remarks', 'G2A - Probably carcinogenic to humans\nSkin', None, None] |
|---|
| ['Component', 'CAS-No.', 'Parameters', 'Value', 'Biological\nspecimen', 'Basis'] | ['acrylamide', '79-06-1', 'N-(2-\nCarbamoyle\nthyl)valine\n(CbEV)', '500pico\nmoles\nper gram\nHemoglo\nbin', 'In blood', 'ACGIH -\nBiological\nExposure Indices\n(BEI)'] | ['', 'Remarks', 'Not critical', None, None, None] | ['', '', 'S-(2-\nCarbamoyle\nthyl)mercap\nturic acid\n(AAMA)', '800µg/g\ncreatinin\ne', 'Urine', 'ACGIH -\nBiological\nExposure Indices\n(BEI)'] | ['', '', 'End of shift', None, None, None] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Body Protection
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
protective clothing
Respiratory protection
required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical statecrystalline
- b) Colorwhite
- c) Odorodorless
- d) Melting point/freezing pointMelting point/range: 82 - 86 °C - lit.
- e) Initial boiling point and boiling range125 °C at 33 hPa - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash point138 °C - closed cup
- i) Autoignition temperatureNo data available
- j) Decomposition temperatureNo data available
- k) pH5.2 - 6 at 500 g/l
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubility200 g/l at 20 °C
- n) Partition coefficient n-octanol/waterlog Pow: -0.9 at 20 °C - Bioaccumulation is not expected.
- o) Vapor pressure2.1 hPa at 84.50 °C 0.04 hPa at 40 °C
- p) Density1.12 g/cm3 at 30 °C
- Relative density1.12 at 30 °C - OPPTS 830.7300
- q) Relative vapor density2.45 - (Air = 1.0)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- Solubility2040 g/L (25°C)
- Henry's Law Constant(x 10-9 atmm3/mol): 3.03 at 20 °C (approximate - calculated from water solubility and vapor pressure)
9.2 Other safety information
Relative vapor density2.45 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with: alkalines
Oxidizing agents
Reducing agents
Bases
Metals
Peroxides acids
Oxidizing agents
Reducing agents
Bases
Metals
Peroxides acids
10.3 Conditions to avoid
Strong heating.
10.4 Incompatible materials
Strong oxidizing agents
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - 177 mg/kg (OECD Test Guideline 401)
Acute toxicity estimate Inhalation - 1.6 mg/l - dust/mist (Expert judgment)
LD50 Dermal - Rabbit - male and female - 1,141 mg/kg (OECD Test Guideline 402)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Skin corrosion/irritation
Acute toxicity estimate Inhalation - 1.6 mg/l - dust/mist (Expert judgment)
LD50 Dermal - Rabbit - male and female - 1,141 mg/kg (OECD Test Guideline 402)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Remarks: Causes skin irritation.
(Regulation (EC) No 1272/2008, Annex VI)
Serious eye damage/eye irritation
(Regulation (EC) No 1272/2008, Annex VI)
Eyes - Rabbit
Result: Eye irritation - 24 h (OECD Test Guideline 405)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Respiratory or skin sensitization
Result: Eye irritation - 24 h (OECD Test Guideline 405)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Maximization Test - Guinea pig
Result: positive (OECD Test Guideline 406)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Germ cell mutagenicity
Result: positive (OECD Test Guideline 406)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
May cause genetic defects.
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster lung cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 473
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: dominant lethal test
Species: Rat
Application Route: Oral
Method: OECD Test Guideline 478
Result: positive
Carcinogenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster lung cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 473
Result: positive
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: dominant lethal test
Species: Rat
Application Route: Oral
Method: OECD Test Guideline 478
Result: positive
Presumed to have carcinogenic potential for humans
Reproductive toxicity
Suspected of damaging fertility.
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Oral - Causes damage to organs through prolonged or repeated exposure.
- Peripheral nervous system
Aspiration hazard
- Peripheral nervous system
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 2 yr - NOAEL (No observed adverse effect level) - 0.5 mg/kg
RTECS: AS3325000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Liver - Irregularities - Based on Human Evidence
RTECS: AS3325000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Liver - Irregularities - Based on Human Evidence
12.1 Toxicity
Toxicity to daphnia flow-through test EC50 - Daphnia magna (Water flea) - 98 mg/l - 48 and other aquatic h invertebrates (US-EPA)
Toxicity to algae static test NOEC - Pseudokirchneriella subcapitata - 56 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria EC50 - Photobacterium phosphoreum - 13,500 mg/l
Remarks: (IUCLID)
Toxicity to NOEC - Cyprinus carpio (Carp) - 5 mg/l - 28 d fish(Chronic toxicity) Remarks: (ECHA)
Toxicity to algae static test NOEC - Pseudokirchneriella subcapitata - 56 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria EC50 - Photobacterium phosphoreum - 13,500 mg/l
Remarks: (IUCLID)
Toxicity to NOEC - Cyprinus carpio (Carp) - 5 mg/l - 28 d fish(Chronic toxicity) Remarks: (ECHA)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 100 % - Readily biodegradable.
(OECD Test Guideline 301D)
Result: 100 % - Readily biodegradable.
(OECD Test Guideline 301D)
12.3 Bioaccumulative potential
Bioaccumulation Oncorhynchus mykiss (rainbow trout) - 72 h - 0.71 mg/l(acrylamide)
Bioconcentration factor (BCF): 1.65
Bioconcentration factor (BCF): 1.65
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 2074
IMDG: 2074
IATA-DGR: 2074
IMDG: 2074
IATA-DGR: 2074
14.2 UN proper shipping name
ADR/RID: ACRYLAMIDE, SOLID
IMDG: ACRYLAMIDE, SOLID
IATA-DGR: Acrylamide, solid
IMDG: ACRYLAMIDE, SOLID
IATA-DGR: Acrylamide, solid
14.3 Transport hazard class(es)
ADR/RID: 6.1
IMDG: 6.1
IATA-DGR: 6.1
IMDG: 6.1
IATA-DGR: 6.1
14.4 Packaging group
ADR/RID: III
IMDG: III
IATA-DGR: III
IMDG: III
IATA-DGR: III
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
Strong oxidizing agents
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Regulations on Occupational Labor Protection in the at workplaces where Toxic
Substances Are Used
Catalogue of Highly Toxic Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Regulations on Occupational Labor Protection in the at workplaces where Toxic
Substances Are Used
Catalogue of Highly Toxic Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.