Chemical Safety Data Sheet MSDS / SDS
AFLATOXIN B2
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: AFLATOXIN B2
- CBnumber: CB0236746
- CAS: 7220-81-7
- EINECS Number: 230-618-8
- Synonyms: AF B2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P262 Do not get in eyes, on skin, or on clothing.
P201 Obtain special instructions before use.
Hazard statements
H340 May cause genetic defects
H350 May cause cancer
Substance
- Product name: AFLATOXIN B2
- Synonyms: AF B2
- CAS: 7220-81-7
- EC number: 230-618-8
- MF: C17H14O6
- MW: 314.29
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. If breathing stops: mouthto-mouth breathing or artificial respiration. Oxygen if necessary. Immediately call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Combustible. Pay attention to flashback. Vapors are heavier than air and may spread along floors. Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Hazardous combustion products
Carbon oxides Nitrogen oxides (NOx)
Specific extinguishing methods
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
4
1
1
| HEALTH | 4 | Very short exposure could cause death or major residual injury (e.g. hydrogen cyanide, phosgene, methyl isocyanate, hydrofluoric acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Che- mizorb® ). Dispose of properly. Clean up affected area.
Handling
Advice on protection against fire and explosionKeep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharge.
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Avoidance of contact
Bases Oxidizing agents Alkali metals Reducing agents acids
Storage
Further information on storage conditionsKeep container tightly closed in a dry and wellventilated place. Keep away from heat and sources of ignition.
Storage class
3, Flammable liquids
Recommended storage temperature
-20 °C
Further information on storage stability
Handle and store under inert gas.
control parameter
Hazard composition and occupational exposure limitsDoes not contain substances with occupational exposure limits.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses
Skin and body protection
Safety glasses
Flame retardant antistatic protective clothing.
Hand protection
Remarks
required
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Flash point2 °C
Method: closed cup - Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Flammability (liquids)No data available
- Burning rateNo data available
- Upper explosion limit / Upper flammability limitNo data available
- Lower explosion limit / Lower flammability limitNo data available
- Vapor pressureNo data available
- Relative vapor densityNo data available
- Relative density1.2564 (rough estimate)
- Density0.782 g/cm3
- Water solubility15mg/L(temperature not stated)
- Partition coefficient: n-octanol/waterNo data available
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- Viscosity, dynamicNo data available
- Viscosity, kinematicNo data available
- Particle characteristics Particle sizeNo data available
- Molecular weight314.29 g/mol
- Oxidizing propertiesnone
- Explosive propertiesNot classified as explosive.
- Flow timeNo data available
- Boiling point/boiling range373.98°C (rough estimate)
- Melting point/ rangeNo data available
- pHNo data available
- Odor ThresholdNo data available
- OdorNo data available
- ColorWhite to off-white
- Appearanceliquid
- Physical stateSolid
- SolubilityDMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12 mg/ml
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Warming.
Incompatible materials
Bases Oxidizing agents Alkali metals Reducing agents acids
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
Acute toxicity estimate Oral - 617 mg/kg (Calculation method)
Acute toxicity estimate Inhalation - 4 h - 11 mg/l - vapor(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Acute toxicity estimate Dermal - 1,500 mg/kg (Calculation method)
Skin corrosion/irritation
Acute toxicity estimate Oral - 617 mg/kg (Calculation method)
Acute toxicity estimate Inhalation - 4 h - 11 mg/l - vapor(Calculation method)
Symptoms: Possible symptoms:, mucosal irritations
Acute toxicity estimate Dermal - 1,500 mg/kg (Calculation method)
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Remarks: Mixture causes serious eye irritation.
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with proper instructions., The onset of symptoms is generally delayed pending con- version to cyanide., Headache, Dizziness, Rash, Cyanosis, excitement, depression,
Drowsiness
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components Acetonitrile
Drowsiness
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Mouse - male and female - 617 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Mouse - male and female - 4 h - 6.022 mg/l - vapor (OECD Test Guideline 403)
Acute toxicity estimate Dermal - 1,500 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
LC50 Inhalation - Mouse - male and female - 4 h - 6.022 mg/l - vapor (OECD Test Guideline 403)
Acute toxicity estimate Dermal - 1,500 mg/kg (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes serious eye irritation.
(OECD Test Guideline 405)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Result: Causes serious eye irritation.
(OECD Test Guideline 405)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Respiratory or skin sensitization
Buehler Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Remarks: (National Toxicology Program)
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: negative
Remarks: Sister chromatid exchange
Test system: Saccharomyces cerevisiae
Result: positive
Remarks: Cytogenetic analysis (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female
Result: negative
Carcinogenicity
Test system: S. typhimurium
Result: negative
Remarks: (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Result: Positive results were obtained in some in vitro tests.
Remarks: (National Toxicology Program)
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Result: negative
Remarks: Sister chromatid exchange
Test system: Saccharomyces cerevisiae
Result: positive
Remarks: Cytogenetic analysis (ECHA)
Test Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Result: negative
Method: OECD Test Guideline 474
Species: Mouse - male and female
Result: negative
No evidence of carcinogenicity in animal studies.
Reproductive toxicity
Animal testing did not show any effects on fertility.
Specific target organ toxicity - single exposure
The substance or mixture is not classified as specific target organ toxicant, single exposure.
Specific target organ toxicity - repeated exposure
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
Aspiration hazard
No aspiration toxicity classification
Ecotoxicity
Components:
Acetonitrile:
Toxicity to fishLC50 (Pimephales promelas (fathead minnow)): 1,640 mg/l Exposure time: 96 h Test Type: flow-through test Analytical monitoring: yes Remarks: (ECHA)
Toxicity to algae/aquatic plants
NOEC (Phaeodactylum tricornutum): 400 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: ISO 10253 GLP: yes ErC50 (Phaeodactylum tricornutum): 9,696 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: ISO 10253 GLP: yes
Toxicity to fish (Chronic toxicity)
NOEC (Oryzias latipes): 102 mg/l End point: mortality Exposure time: 21 d Test Type: flow-through test Analytical monitoring: yes Method: OECD Test Guideline 204 GLP: yes
Toxicity to microorganisms
EC50 (activated sludge): > 1,000 mg/l Exposure time: 30 min Test Type: static test Method: OECD Test Guideline 209 GLP: yes
Persistence and degradability
Components:
Acetonitrile:
BiodegradabilityInoculum: activated sludge, non-adapted Concentration: 684 mg/l Result: Readily biodegradable. Biodegradation: 70 % Exposure time: 21 d Method: OECD Test Guideline 310 GLP: yes
Stability in water
Degradation half life (DT50): > 9,999 d pH: 7 Hydrolysis: at 25 °C Remarks: (calculated) Hydrolyzes slowly.
Bioaccumulative potential
Components:
Acetonitrile:
BioaccumulationRemarks: No bioaccumulation is to be expected (log Pow <= 4).
Partition coefficient: noctanol/water
log Pow: -0.54 (25 °C) Remarks: Bioaccumulation is not expected.
Mobility in soil
Components:
Acetonitrile:
Distribution among environmental compartmentsAdsorption/Soil Koc: 16, log Koc: 1.21 Remarks: Mobile in soils (Lit.)
Stability in soil
Dissipation time: > 168 - < 672 h Method: (calculated) Remarks: Not expected to adsorb on soil.
Other adverse effects
Components:
Acetonitrile:
Additional ecological informationAvoid release to the environment.
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 1648
Proper shipping name : Acetonitrile solution
Class : 3
Packing group : II
Labels : Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 364
Packing instruction (passenger aircraft) : 353
Proper shipping name : Acetonitrile solution
Class : 3
Packing group : II
Labels : Class 3 - Flammable liquids
Packing instruction (cargo aircraft) : 364
Packing instruction (passenger aircraft) : 353
IMDG-Code
UN number : UN 1648
Proper shipping name : ACETONITRILE SOLUTION
Class : 3
Packing group : II
Labels : 3
EmS Code : F-E, S-D
Marine pollutant : no
Proper shipping name : ACETONITRILE SOLUTION
Class : 3
Packing group : II
Labels : 3
EmS Code : F-E, S-D
Marine pollutant : no
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National regulation GB 6944/12268
UN number : UN 1648
Proper shipping name : ACETONITRILE
Class : 3
Packing group : II
Labels : 3
National regulation GB 6944/12268
UN number : UN 1648
Proper shipping name : ACETONITRILE
Class : 3
Packing group : II
Labels : 3
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Listed
Identification of Major Hazard Installations for Hazardous Chemicals (GB 18218)
No. / Code Chemical name / Category Threshold quantity
W5.3 Flammable liquids 1,000 t
Hazardous Chemicals for Priority Management
Not listed under SAWS
Catalogue of Specially Controlled Hazardous
Not listed Chemicals
List of Explosive Precursors
Not listed
Regulations on Occupational Labor Protection in the at workplaces where
Toxic Substances Are Used
Catalogue of Highly Toxic Chemicals
Not listed
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not listed
Regulation on the Administration of Precursor Chemicals
Catalogue and Classification of Precursor Chemicals
Not listed
Regulations on the Administration of Controlled Chemicals
List of Controlled Chemicals
Not listed
Regulations of Ozone Depleting Substances Management
List of Controlled Ozone Depleting Substances
Not listed
List of Controlled Ozone Depleting Substances Import and Export
Not listed
Environmental Protection Law
List of Priority Controlled Chemicals
Not listed
List of Key Controlled New Pollutants
Not listed
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
GBZ 2.1-2007
Occupational exposure limits for hazardous agents in the workplace - Chemical hazardous agents.
ACGIH / TWA
8-hour, time-weighted average
GBZ 2.1-2007 / PC-TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
Permissible concentration - time weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.
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