Chemical Safety Data Sheet MSDS / SDS
Alizarin
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Alizarin
- CBnumber: CB4854164
- CAS: 72-48-0
- EINECS Number: 200-782-5
- Synonyms: Alizarin Red;CI 58000
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P272 Contaminated work clothing should not be allowed out of the workplace.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Hazard statements
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H410 Very toxic to aquatic life with long lasting effects
Substance
- Product name: Alizarin
- Synonyms: Alizarin Red;CI 58000
- CAS: 72-48-0
- EC number: 200-782-5
- MF: C14H8O4
- MW: 240.21
General advice
Show this safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Specific hazards during fire fighting
Combustible. Development of hazardous combustion gases or vapours possible in the event of fire.
Hazardous combustion products
Nature of decomposition products not known.
Specific extinguishing methods
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
1
0
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Handling
Avoidance of contactStrong oxidizing agents Strong bases
Storage
Further information on storage conditionsTightly closed. Dry.
Storage class
11, Combustible Solids
Recommended storage temperature
Recommended storage temperature see product label.
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionFor nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
Use respirators and components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).
Eye/face protection
Use respirators and components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles
Skin and body protection
Tightly fitting safety goggles
protective clothing
Hand protection
Remarks
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Hygiene measures
The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Information on basic physicochemical properties
- Physical stateFine Powder
- SolubilitySolubility Virtually insoluble in water; moderately soluble in ethanol, soluble in benzene, toluene, Ixylene, pyridine, acetic acid
- Particle characteristics Particle sizeNo data available
- Molecular weight240.21 g/mol
- Oxidizing propertiesnone
- Explosive propertiesNo data available
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterlog Pow: 2.91 (20 °C)
Method: OECD Test Guideline 117
GLP: yes Bioaccumulation is not expected. - Water solubility0.483 g/l (20 °C)
Method: OECD Test Guideline 105
GLP: yes - Density1.06 g/mL at 20 °C
- Relative density1.575 (20 °C)
Method: OECD Test Guideline 109
GLP: yes - Relative vapor densityNo data available
- Vapor pressureNo data available
- Lower explosion limit / Lower flammability limitNo data available
- Upper explosion limit / Upper flammability limitNo data available
- Burning rateNo data available
- Flammability (liquids)No data available
- Flammability (solid, gas)No data available
- Evaporation rateNo data available
- Flash point430°C subl.
- Boiling point/boiling range430 °C
- Melting point/ range279 - 283 °C
Method: lit. - pH5.5～7.2
- Odor ThresholdNo data available
- OdorNo data available
- Coloryellow
- Appearancesolid
Reactivity
The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Chemical stability
The product is chemically stable under standard ambi- ent conditions (room temperature) .
Possibility of hazardous reactions
Stable under recommended storage conditions.
Conditions to avoid
no information available
Incompatible materials
Strong oxidizing agents Strong bases
Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - > 2,000 mg/kg (OECD Test Guideline 423)
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Skin - In vitro study
Result: No skin irritation (OECD Test Guideline 439)
Serious eye damage/eye irritation
Result: No skin irritation (OECD Test Guideline 439)
Eyes - Rabbit
Result: Eye irritation - 24 h
Remarks: (RTECS)
Respiratory or skin sensitization
Result: Eye irritation - 24 h
Remarks: (RTECS)
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Species: Mouse
Application Route: Oral
Result: negative
Remarks: (ECHA)
Carcinogenicity
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Species: Mouse
Application Route: Oral
Result: negative
Remarks: (ECHA)
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: CB6580000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Ecotoxicity
Components:
alizarine:
Toxicity to fishLC50 (Oryzias latipes): 1.1 mg/l Exposure time: 48 h Remarks: (ECOTOX Database)
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 1.58 mg/l End point: Immobilization Exposure time: 48 h Test Type: semi-static test Analytical monitoring: yes Method: OECD Test Guideline 202 GLP: yes
Ecotoxicology Assessment
Acute aquatic toxicityThis product has no known ecotoxicological effects.
Chronic aquatic toxicity
Very toxic to aquatic life with long lasting effects.
Persistence and degradability
Components:
alizarine:
Biodegradabilityaerobic Inoculum: activated sludge, non-adapted Concentration: 20.1 mg/l Result: Not readily biodegradable. Biodegradation: 19.6 % Exposure time: 28 d
Bioaccumulative potential
Components:
alizarine:
Partition coefficient: noctanol/waterlog Pow: 2.91 (20 °C) Method: OECD Test Guideline 117 GLP: yes Remarks: Bioaccumulation is not expected.
Mobility in soil
No data available
Other adverse effects
No data available
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 3077
Proper shipping name : Environmentally hazardous substance, solid, n.o.s.
(alizarine)
Class : 9
Packing group : III
Labels : Class 9 - Miscellaneous dangerous substances and articles
Packing instruction (cargo aircraft) : 956
Packing instruction (passenger aircraft) : 956
Proper shipping name : Environmentally hazardous substance, solid, n.o.s.
(alizarine)
Class : 9
Packing group : III
Labels : Class 9 - Miscellaneous dangerous substances and articles
Packing instruction (cargo aircraft) : 956
Packing instruction (passenger aircraft) : 956
IMDG-Code
UN number : UN 3077
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(alizarine)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(alizarine)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
JT/T 617
UN number : UN 3077
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(alizarine)
Class : 9
Packing group : III
Labels : 9
Environmentally hazardous : no
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(alizarine)
Class : 9
Packing group : III
Labels : 9
Environmentally hazardous : no
Special precautions for user
Remarks : EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous
Goods > 5L for liquids or > 5kg for solids.
Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
Goods > 5L for liquids or > 5kg for solids.
Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Hazardous Chemicals for Priority Management
Not applicable under SAWS
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Not applicable
Full text of other abbreviations
AIIC - Australian Inventory of Industrial Chemicals
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonised System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organisation
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardisation
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
MERCOSUR - The Agreement for the Facilitation of the Transport of Dangerous Goods
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organisation for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
ANTT - National Agency forTransport by Land of Brazil
ASTM - American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen, Mutagen or Reproductive Toxicant
DIN -Standard of the German Institute for Standardisation
DSL - Domestic SubstancesList (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS - Emergency Schedule
ENCS - Existing and NewChemical Substances (Japan)
ErCx - Concentration associated with x% growth rate response
ERG - Emergency Response Guide
GHS - Globally Harmonised System
GLP - Good Laboratory Practice
IARC - International Agency for Research on Can- cer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 -Half maximal inhibitory concentration
ICAO - International Civil Aviation Organiza- tion
IECSC - Inventory of Existing Chemical Substances in China
IMDG - Interna- tional Maritime Dangerous Goods
IMO - International Maritime Organisation
ISHL -Industrial Safety and Health Law (Japan)
ISO - International Organisation forStandardisation
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concen- tration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pol- lution from Ships
MERCOSUR - The Agreement for the Facilitation of the Transport of Dangerous Goods
n.o.s. - Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Ef- fect Level
NOELR - No Observable Effect Loading Rate
NOM - Official MexicanNorm
NTP - National Toxicology Program
NZIoC - New Zealand Inventory of Chem- icals
OECD - Organisation for Economic Co-operation and Development
OPPTS - Of- fice of Chemical Safety and Pollution Prevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - Philippines Inventory of Chemicals and Chemical Sub- stances
(Q)SAR - (Quantitative) Structure Activity Relationship
REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning theRegistration, Evaluation, Authorisation and Restriction of Chemicals
SADT - Self-Accelerating Decomposition Temperature
SDS - Safety Data Sheet
TCSI - TaiwanChemical Substance Inventory
TDG - Transportation of Dangerous Goods
TECI -Thailand Existing Chemicals Inventory
TSCA - Toxic Substances Control Act (UnitedStates)
UN - United Nations
UNRTDG - United Nations Recommendations on theTransport of Dangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
WHMIS - Workplace Hazardous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.