Chemical Safety Data Sheet MSDS / SDS

DIETHYL ETHER-D10

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: DIETHYL ETHER-D10
  • CBnumber: CB4777258
  • CAS: 2679-89-2
  • EINECS Number: 220-235-4
  • Synonyms: ETHER-D10;ETHYL-D5 ETHER

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P240 Ground/bond container and receiving equipment.
P233 Keep container tightly closed.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H336 May cause drowsiness or dizziness
H302 Harmful if swallowed
H224 Extremely flammable liquid and vapour

SECTION 3: Composition/information on ingredients

Substance

  • Product name: DIETHYL ETHER-D10
  • Synonyms: ETHER-D10;ETHYL-D5 ETHER
  • CAS: 2679-89-2
  • EC number: 220-235-4
  • MF: C4D10O
  • MW: 84.18

SECTION 4: First aid measures

4.1 Description of first-aid measures

General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media
Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.

5.3 Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.

5.4 Further information

Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

2
4
1
HEALTH 2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE 4 Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas)
REACT 1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)
SPEC. HAZ.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.

6.2 Environmental precautions

Do not let product enter drains. Risk of explosion.

6.3 Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Light sensitive. Test for peroxide formation periodically and before distillation.
Storage class
Storage class (TRGS 510): 3: Flammable liquids

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

8.2 Exposure controls

Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • a) Physical stateliquid
  • b) ColorColorless
  • c) OdorNo data available
  • d) Melting point/freezing pointMelting point/ range: -116 °C - lit.
  • e) Initial boiling point and boiling range33 - 34 °C - lit.
  • f) Flammability (solid, gas)No data available
  • g) Upper/lower flammability or explosive limits1.7-36%(V)
  • h) Flash point-40 °C - closed cup
  • i) Autoignition temperatureNo data available
  • j) Decomposition temperatureNo data available
  • k) pHNo data available
  • l) ViscosityViscosity, kinematic: No data available
    Viscosity, dynamic: No data available
  • m) Water solubilityNo data available
  • n) Partition coefficient n-octanol/waterNo data available
  • o) Vapor pressureNo data available
  • p) Density0,801 g/mL at 25 °C 0,801 g/cm3 at 25 °C
  • Relative density0.801 g/mL at 25 °C
  • q) Relative vapor densityNo data available
  • r) Particle characteristicsNo data available
  • s) Explosive propertiesNo data available
  • t) Oxidizing propertiesNo data available
  • Solubility69g/l

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Reactivity

Formation of peroxides possible.
Vapors may form explosive mixture with air.

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .
May form peroxides of unknown stability.

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

Warming.
Moisture.

10.5 Incompatible materials

No data available

10.6 Hazardous decomposition products

Peroxides
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - 1.211 mg/kg
Remarks: (RTECS)
The value is given in analogy to the following substances: Diethyl ether
Symptoms: Risk of aspiration upon vomiting., Aspiration may cause pulmonary edema and pneumonitis.
Acute toxicity estimate Oral - 1.211 mg/kg (ATE value derived from LD50/LC50 value)
LC50 Inhalation - Mouse - 4 h - 97,5 mg/l - vapor
Remarks: (RTECS)
The value is given in analogy to the following substances: Diethyl ether
Symptoms: mucosal irritations
LD50 Dermal - Rabbit - male - > 20.000 mg/kg (OECD Test Guideline 402)
Remarks: (ECHA)
The value is given in analogy to the following substances: Diethyl ether
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Remarks: The value is given in analogy to the following substances: Diethyl ether
Remarks: Dermatitis
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Remarks: The value is given in analogy to the following substances: Diethyl ether
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Remarks: The value is given in analogy to the following substances: Diethyl ether
Germ cell mutagenicity
Test Type: Micronucleus test
Test system: Human lymphocytes
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 487
Result: negative
Remarks: The value is given in analogy to the following substances: Diethyl etherTest
Type: In vitro mammalian cell gene mutation test
Test system: Mouse lymphoma test
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: The value is given in analogy to the following substances: Diethyl etherTest
Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: The value is given in analogy to the following substances: Diethyl ether
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Intraperitoneal
Method: OECD Test Guideline 474
Result: negative
Remarks: The value is given in analogy to the following substances: Diethyl ether
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Oral - May cause drowsiness or dizziness. - Central nervous system
Remarks: The value is given in analogy to the following substances: Diethyl ether
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2

11.2 Additional Information

Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Repeated dose toxicity - Rat - male and female - Oral - 13 Weeks - NOAEL (No observed adverse effect level) - 500 mg/kg - LOAEL (Lowest observed adverse effect level) - 2.000 mg/kg
Remarks: (ECHA)
The value is given in analogy to the following substances: Diethyl ether
Inhalation may provoke the following symptoms:
Cough, chest pain, Difficulty in breathing, Dizziness, Drowsiness, Contact with eyes can cause:, Redness, Provokes tears., Blurred vision, Prolonged or repeated exposure to skin causes defatting and dermatitis.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Narcotic!
After absorption:
Salivation ataxia (impaired locomotor coordination) inebriation
Unconsciousness
Coma
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Liver - Ingestion may provoke the following symptoms:, Irregularities - Based on Human
Evidence

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to fish LC50 - Lepomis macrochirus (Bluegill sunfish) - > 10.000 mg/l - 96 h
Remarks: (IUCLID)
The value is given in analogy to the following substances: Diethyl ether
Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 1.380 mg/l - 48 h and other aquatic Remarks: (IUCLID) invertebrates The value is given in analogy to the following substances: Diethyl ether
Toxicity to algae static test ErC50 - Desmodesmus subspicatus (green algae) - > 100 mg/l - 72 h (OECD Test Guideline 201)
Remarks: The value is given in analogy to the following substances:
Diethyl ether static test NOEC - Desmodesmus subspicatus (green algae) - 100 mg/l - 72 h (OECD Test Guideline 201)
Remarks: The value is given in analogy to the following substances:
Diethyl ether
Toxicity to bacteria static test EC50 - activated sludge - 21.000 mg/l - 3 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances:
Diethyl ether static test NOEC - activated sludge - 42 mg/l - 3 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances:
Diethyl ether
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - > 100 mg/l - and other aquatic 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity) Remarks: The value is given in analogy to the following substances:
Diethyl ether

12.2 Persistence and degradability

Not readily biodegradable.

12.3 Bioaccumulative potential

No bioaccumulation is to be expected (log Pow <= 4).

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

12.6 Endocrine disrupting properties

Product:
Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission
Delegated regulation (EU) 2017/2100 or Commission
Regulation (EU) 2018/605 at levels of 0.1% or higher.

12.7 Other adverse effects

No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods

No data available

SECTION 14: Transport information

14.1 UN number

ADR/RID: 1155
IMDG: 1155
IATA: 1155

14.2 UN proper shipping name

ADR/RID: DIETHYL ETHER
IMDG: DIETHYL ETHER
IATA: Diethyl ether

14.3 Transport hazard class(es)

ADR/RID: 3
IMDG: 3
IATA: 3

14.4 Packaging group

ADR/RID: I
IMDG: I
IATA: I

14.5 Environmental hazards

ADR/RID: no
IMDG Marine pollutant: no
IATA: no

14.6 Special precautions for user

Tunnel restriction code : (D/E)
Further information : No data available

14.7 Maritime transport in bulk according to IMO instruments

Not applicable for product as supplied.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
National legislation
Seveso III: Directive 2012/18/EU of the P5a FLAMMABLE LIQUIDS
European Parliament and of the Council on the control of major-accident hazards involving dangerous substances.
Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of other abbreviations

ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways
ADR - Agreement concerning the International Carriage ofDangerous Goods by Road
AIIC - Australian Inventory of Industrial Chemicals
ASTM -American Society for the Testing of Materials
bw - Body weight
CMR - Carcinogen,Mutagen or Reproductive Toxicant
DIN - Standard of the German Institute forStandardisation
DSL - Domestic Substances List (Canada)
ECx - Concentration associated with x% response
ELx - Loading rate associated with x% response
EmS -Emergency Schedule
ENCS - Existing and New Chemical Substances (Japan)
ErCx -Concentration associated with x% growth rate response
GHS - Globally HarmonizedSystem
GLP - Good Laboratory Practice
IARC - International Agency for Research onCancer
IATA - International Air Transport Association
IBC - International Code for theConstruction and Equipment of Ships carrying Dangerous Chemicals in Bulk
IC50 - Half maximal inhibitory concentration
ICAO - International Civil Aviation Organization
IECSC - Inventory of Existing Chemical Substances in China
IMDG - InternationalMaritime Dangerous Goods
IMO - International Maritime Organization
ISHL - IndustrialSafety and Health Law (Japan)
ISO - International Organisation for Standardization
KECI - Korea Existing Chemicals Inventory
LC50 - Lethal Concentration to 50 % of a test population
LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose)
MARPOL - International Convention for the Prevention of Pollution from Ships
n.o.s. -Not Otherwise Specified
NO(A)EC - No Observed (Adverse) Effect Concentration
NO(A)EL - No Observed (Adverse) Effect Level
NOELR - No Observable Effect LoadingRate
NZIoC - New Zealand Inventory of Chemicals
OECD - Organization for EconomicCo-operation and Development
OPPTS - Office of Chemical Safety and PollutionPrevention
PBT - Persistent, Bioaccumulative and Toxic substance
PICCS - PhilippinesInventory of Chemicals and Chemical Substances
(Q)SAR - (Quantitative) StructureActivity Relationship
REACH - Regulation (EC) No 1907/2006 of the EuropeanParliament and of the Council concerning the Registration, Evaluation, Authorisation andRestriction of Chemicals
RID - Regulations concerning the International Carriage ofDangerous Goods by Rail
SADT - Self-Accelerating Decomposition Temperature
SDS -Safety Data Sheet
TCSI - Taiwan Chemical Substance Inventory
TECI - ThailandExisting Chemicals Inventory
TSCA - Toxic Substances Control Act (United States)
UN - United Nations
UNRTDG - United Nations Recommendations on the Transport ofDangerous Goods
vPvB - Very Persistent and Very Bioaccumulative
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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