Chemical Safety Data Sheet MSDS / SDS
ISOAMYL NITRATE
Revision Date:2026-03-20Revision Number:1
Product identifier
- Product name: ISOAMYL NITRATE
- CBnumber: CB3341522
- CAS: 543-87-3
- EINECS Number: 208-852-7
- Synonyms: nitritod’amile ;SOAMYL NITRATE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P501 Dispose of contents/container to..…
P403+P235 Store in a well-ventilated place. Keep cool.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash skin thouroughly after handling.
P240 Ground/bond container and receiving equipment.
P233 Keep container tightly closed.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H319 Causes serious eye irritation
H315 Causes skin irritation
H226 Flammable liquid and vapour
Substance
- Product name: ISOAMYL NITRATE
- Synonyms: nitritod’amile ;SOAMYL NITRATE
- CAS: 543-87-3
- EC number: 208-852-7
- MF: C5H11NO3
- MW: 133.15
If inhaled
Remove person to fresh air and keep comfortable for breathing. Get medical advice/ attention if you feel unwell.
In case of skin contact
Take off all contaminated clothing immediately. If on skin, rinse well with water. If skin irritation occurs: Get medical advice/ attention.
In case of eye contact
Rinse with plenty of water. If easy to do, remove contact lens, if worn. If eye irritation persists: Get medical advice/ attention.
If swallowed
Get medical advice/ attention. Rinse mouth.
Most important symptoms and effects, both acute and delayed
None known.
Suitable extinguishing media
Dry powder, Foam, Water spray, Carbon dioxide (CO2)
Specific hazards during fire fighting
May explode in fire.
Specific extinguishing methods
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Immediately evacuate personnel to safe areas. Cool closed containers exposed to fire with water spray. Remove undamaged containers from fire area if it is safe to do so.
Special protective equipment for fire-fighters
Use personal protective equipment.
NFPA 704
1
2
2
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 2 | Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Wear suitable protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Environmental precautions
Prevent product from entering drains.
Methods and materials for containment and cleaning up
Collect as much of the spill as possible with a suitable absorbent material.
Handling
Technical measuresPrevent generation of vapor or mist. Take precautionary measures against static discharge. Use explosion-proof equipment.
Local/Total ventilation
Ensure adequate ventilation. Use a local exhaust ventilation.
Advice on safe handling
Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not subject to grinding, shock or friction. Wash hands and face thoroughly after handling.
Avoidance of contact
Oxidizing agents, Reducing agents, Strong acids
Storage
Conditions for safe storageKeep container tightly closed. Store in a cool and shaded area. Keep in a well-ventilated place. Use explosion-proof equipment. Keep under inert gas. Avoid shock and friction. Avoid exposure to light.
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
Engineering measures
Install a closed system or local exhaust.
Also install safety shower and eye bath.
Also install safety shower and eye bath.
Personal protective equipment
Respiratory protectionGas mask
Eye/face protection
Safety glasses
Face-shield
Skin and body protection
Face-shield
Protective suit
Hand protection
Protective gloves *Use personal protective equipment(PPE) approved under appropriate government standards and follow local and national regulations.
Information on basic physicochemical properties
- Physical stateclear liquid
- Molecular weight133.15 g/mol
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterNo data available
- Solubility in other solventssoluble Solvent: Ether soluble Solvent: Alcohol
- Water solubilityslightly soluble
- Relative density1.00
- Relative vapor density4.6
- Vapor pressure0.4 kPa (20 °C)
- Lower explosion limit / Lower flammability limitNo data available
- Upper explosion limit / Upper flammability limitNo data available
- FlammabilityNo data available
- Evaporation rateNo data available
- Flash point49℃
- Boiling point/boiling range148 °C
- Melting point/freezing pointNo data available
- pHNo data available
- Odor ThresholdNo data available
- OdorNo data available
- Colorcolorless
- Appearanceliquid
Reactivity
No data available
Chemical stability
Stable under normal conditions.
Possibility of hazardous reactions
May explosively decompose on heating, shock, friction, etc.
Conditions to avoid
Heat. Electrical spark Open flame Electrostatic discharge Avoid shock and friction. Exposure to air. Exposure to light.
Incompatible materials
Oxidizing agents, Reducing agents, Strong acids
Hazardous decomposition products
Carbon monoxide, Carbon dioxide (CO2), Nitrogen oxides (NOx)
Acute toxicity
Components
Isoamyl Nitrate
Acute toxicity (other routes of administration)
LD50 (Mouse): 480 mg/kg Application Route: Intraperitoneal injection
Skin corrosion/irritation
Product
Result
Skin irritation
Components
Isoamyl Nitrate
Result
Skin irritation
Serious eye damage/eye irritation
Product
Result
Eye irritation
Components
Isoamyl Nitrate
Result
Eye irritation
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2.
Germ cell mutagenicity
Classified based on available data. For more details, see section 2.
Carcinogenicity
Classified based on available data. For more details, see section 2.
Reproductive toxicity
Classified based on available data. For more details, see section 2.
STOT-single exposure
Classified based on available data. For more details, see section 2.
STOT-repeated exposure
Classified based on available data. For more details, see section 2.
Repeated dose toxicity
Classified based on available data. For more details, see section 2.
Aspiration toxicity
Classified based on available data. For more details, see section 2.
RTECS No.
NT0187000 (Isoamyl Nitrate)
Ecotoxicity
No data available
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Other adverse effects
No data available
Disposal methods
Waste from residuesDisposal in accordance with local and national regulations. Take precautions against ignition or explode. Entrust disposal to a licensed waste disposal company.
Contaminated packaging
Disposal in accordance with local and national regulations. Before disposal of used container, remove contents completely.
International Regulations
IATA-DGR
UN/ID No.UN 1112
Proper shipping name
Amyl nitrate
Class
3
Packing group
III
IMDG-Code
UN numberUN 1112
Proper shipping name
AMYL NITRATE
Class
3
Packing group
III
EmS Code
F-E, S-D
Domestic regulation
GB 6944/12268
UN numberUN 1112
Proper shipping name
AMYL NITRATE
Class
3
Packing group
III
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous ChemicalsListed
The ingredients of this product are reported in the following inventories
CH BAGREGOn the inventory, or in compliance with the inventory
TSCA
Substance(s) not active on TSCA inventory
AICS
Not in compliance with the inventory
DSL
None of the components of this product are on the Canadian DSL, but all are on the NDSL
Isoamyl Nitrate
ENCS
Isoamyl Nitrate
On the inventory, or in compliance with the inventory
ISHL
On the inventory, or in compliance with the inventory
KECI
On the inventory, or in compliance with the inventory
PICCS
Not in compliance with the inventory
IECSC
On the inventory, or in compliance with the inventory
NZIoC
Not in compliance with the inventory
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.