Chemical Safety Data Sheet MSDS / SDS
Nitroethane
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Nitroethane
- CBnumber: CB9854402
- CAS: 79-24-3
- EINECS Number: 201-188-9
- Synonyms: nitro-ethan ;C2H5NO2
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P201 Obtain special instructions before use.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P370+P378 In case of fire: Use … for extinction.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H332 Harmful if inhaled
H226 Flammable liquid and vapour
H302 Harmful if swallowed
H331 Toxic if inhaled
H412 Harmful to aquatic life with long lasting effects
H341 Suspected of causing genetic defects
H350 May cause cancer
Substance
- Product name: Nitroethane
- Synonyms: nitro-ethan ;C2H5NO2
- CAS: 79-24-3
- EC number: 201-188-9
- MF: C2H5NO2
- MW: 75.07
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaWater Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
Nitrogen oxides (NOx)
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
2
3
3
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 3 | Capable of detonation or explosive decomposition but requires a strong initiating source, must be heated under confinement before initiation, reacts explosively with water, or will detonate if severely shocked (e.g. ammonium nitrate, cesium, hydrogen peroxide) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ).
Dispose of properly. Clean up affected area.
Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Storage class
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['nitroethane', '79-24-3', 'PC-TWA', '300 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] | ['', 'Remarks', 'G2B - Possibly carcinogenic to humans', None, None] |
|---|
8.2 Exposure controls
Appropriate engineering controlsChange contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
required
Body Protection
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateclear, liquid
- b) Colorlight yellow
- c) OdorNo data available
- d) Melting point/freezing pointMelting point/range: -90 °C - lit.
- e) Initial boiling point and boiling range114 - 115 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsLower explosion limit: 3.4 %(V)
- h) Flash point31 °C - closed cup - Regulation (EC) No. 440/2008, Annex, A.9
- i) Autoignition temperature414 °C at 1,013 hPa
- j) Decomposition temperatureNo data available
- k) pH6 (1g/l, H2O, 25℃)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: 0.64 mPa.s at 25 °C - m) Water solubility48 g/l at 25 °C
- n) Partition coefficient n-octanol/waterlog Pow: 0.162 at 22.4 °C - Bioaccumulation is not expected.
- o) Vapor pressure20.8 hPa at 20 °C
- p) Density1.045 g/cm3 at 25 °C - lit.
- Relative density1.05 at 20 °C
- q) Relative vapor density2.59 - (Air = 1.0)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNot classified as explosive.
- t) Oxidizing propertiesnone
- Solubilityacetone: soluble(lit.)
- Henry's Law Constant3.50 at 20.00 °C, 5.86 at 30.00 °C, 9.38 at 40.00 °C, 15.7 at 50.00 °C (inert gas stripping, Bene and Dohnal, 1999)
- Dielectric constant19.7（20℃）
9.2 Other safety information
Surface tension72 mN/m at 21 °C - OECD Test Guideline 115
Relative vapor density
2.59 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with:
Oxidizing agents strong reducing agents
Strong acids
Strong bases
Oxidizing agents strong reducing agents
Strong acids
Strong bases
10.3 Conditions to avoid
Avoid moisture.
Heating.
Heating.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - female - 1,083 mg/kg (OECD Test Guideline 401)
Symptoms: Nausea, Vomiting, Diarrhea, Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Acute toxicity estimate Inhalation - 4 h - 11.1 mg/l - vapor (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: mucosal irritations, Cough, Shortness of breath
Dermal: No data available
Skin corrosion/irritation
Symptoms: Nausea, Vomiting, Diarrhea, Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
Acute toxicity estimate Inhalation - 4 h - 11.1 mg/l - vapor (Expert judgment)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Symptoms: mucosal irritations, Cough, Shortness of breath
Dermal: No data available
Skin - Rabbit
Result: No skin irritation - 24 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: No skin irritation - 24 h (OECD Test Guideline 404)
Eyes - Rabbit
Result: No eye irritation
Remarks: (ECHA)
Respiratory or skin sensitization
Result: No eye irritation
Remarks: (ECHA)
Sensitisation test: - Guinea pig
Result: negative
Remarks: (ECHA)
Germ cell mutagenicity
Result: negative
Remarks: (ECHA)
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Bone marrow
Application Route: Oral
Result: negative
Carcinogenicity
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Bone marrow
Application Route: Oral
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Suspected of damaging the unborn child.
Suspected of damaging fertility.
Specific target organ toxicity - single exposure
Suspected of damaging fertility.
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 28 Days - LOAEL (Lowest observed adverse effect level) - 100 mg/kg
Remarks: (ECHA)
RTECS: KI5600000
Kidney injury may occur., Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After absorption:
Systemic effects:
CNS disorders
Headache
Dizziness
Unconsciousness
Toxic effect on:
Liver
Kidney
The following applies to aliphatic nitro compounds in general: weak methaemoglobin producer.
Handle in accordance with good industrial hygiene and safety practice.
Remarks: (ECHA)
RTECS: KI5600000
Kidney injury may occur., Absorption into the body leads to the formation of methemoglobin which in sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After absorption:
Systemic effects:
CNS disorders
Headache
Dizziness
Unconsciousness
Toxic effect on:
Liver
Kidney
The following applies to aliphatic nitro compounds in general: weak methaemoglobin producer.
Handle in accordance with good industrial hygiene and safety practice.
12.1 Toxicity
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - > 21.9 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 17.4 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - 310 mg/l - 0.5 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances: 1-nitropropane
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - 2.44 mg/l - and other aquatic 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 17.4 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - 310 mg/l - 0.5 h (OECD Test Guideline 209)
Remarks: The value is given in analogy to the following substances: 1-nitropropane
Toxicity to daphnia semi-static test NOEC - Daphnia magna (Water flea) - 2.44 mg/l - and other aquatic 21 d invertebrates(Chronic (OECD Test Guideline 211) toxicity)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 5 d
Result: 23.9 % - Inherently biodegradable.
Remarks: (ECHA)
Ratio BOD/ThBOD < 0.1 %
Result: 23.9 % - Inherently biodegradable.
Remarks: (ECHA)
Ratio BOD/ThBOD < 0.1 %
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Discharge into the environment must be avoided.
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 2842
IMDG: 2842
IATA-DGR: 2842
IMDG: 2842
IATA-DGR: 2842
14.2 UN proper shipping name
ADR/RID: NITROETHANE
IMDG: NITROETHANE
IATA-DGR: Nitroethane
IMDG: NITROETHANE
IATA-DGR: Nitroethane
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: III
IMDG: III
IATA-DGR: III
IMDG: III
IATA-DGR: III
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.