Chemical Safety Data Sheet MSDS / SDS

phenoxybenzamine

Revision Date:2026-03-22Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: phenoxybenzamine
CBnumber: CB1933947
CAS: 59-96-1
EINECS Number: 2004468
Synonyms: Phenoxybenzamin

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordWarning

Precautionary statements

P308+P313 IF exposed or concerned: Get medical advice/attention.

P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P270 Do not eat, drink or smoke when using this product.

P264 Wash skin thouroughly after handling.

P202 Do not handle until all safety precautions have been read and understood.

Hazard statements

No data available

SECTION 3: Composition/information on ingredients

Substance

Product name: phenoxybenzamine
Synonyms: phenoxy,Phenoxybenzamin
CAS: 59-96-1
EC number: 2004468
MF: C18H22ClNO
MW: 303.83

SECTION 4: First aid measures

4.1 Description of necessary first-aid measures

General advice

no data available

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control
Center immediately.

4.2 Most important symptoms/effects, acute and delayed

Treatment: Stabilization. Establish adequate respiratory function. Normal tidal volume: 10-15 ml/kg. Endotracheal intubation with assisted ventilation may be required. Gut Decontamination. Emesis induction is indicated unless the patient is comatose, is convulsing, or has no gag reflex. If these are present, endotracheal intubation must be performed with a cuffed endotracheal tube before a large-bore gastric tube is inserted for gastric lavage. ... Activated Charcoal. Adults, 50-100 g; children, 15-30 g in aqueous or sorbital slurry, after emesis is induced or into the gastric tube after lavage. Cathartic. Magnesium sulfate or sodium sulfate; adult, 30 g children, 250 mg/kg.
No studies on efficacy are available with this group of drugs. Elimination enhancement. In view of the extensive protein binding and extensive volume of distribution of some drugs of this group, it is unlikely that hemodialysis or peritoneal dialysis would be effective. In any case, no studies exist to demonstrate such efficacy. Most cases are amenable to good supportive therapy. Antidotes. There are no antidotes. alpha-Adrenergic blockers

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Use dry chemical, carbon dioxide or alcohol-resistant foam.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

6.2 Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark- proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the riskelimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Odourno data available
ColorCRYSTALS FROM PETROLEUM ETHER
Physical stateSolid
Particle characteristicsno data available
Relative vapour densityno data available
Density and/ or relative density1.102g/cm3
Vapour pressureno data available
N-octanol-water partition coefficientno data available
Solubilityno data available
Kinematic viscosityno data available
pHno data available
Decomposition temperatureno data available
Auto-ignition temperatureno data available
Flash point184.5°C
Lower and upper explosion limit/flammability limitno data available
Flammabilityno data available
Boilingpoint or initial boiling point and boiling range381.5°C at 760mmHg
Melting point/ freezing point38-40°C

SECTION 10: Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

no data available

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available