Chemical Safety Data Sheet MSDS / SDS
Propargyl alcohol
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Propargyl alcohol
- CBnumber: CB4393700
- CAS: 107-19-7
- EINECS Number: 203-471-2
- Synonyms: prop-2-yn-1-ol;PROPYNOL
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H411 Toxic to aquatic life with long lasting effects
H373 May cause damage to organs through prolonged or repeated exposure
H314 Causes severe skin burns and eye damage
H301 Toxic if swalloed
H226 Flammable liquid and vapour
Substance
- Product name: Propargyl alcohol
- Synonyms: prop-2-yn-1-ol;PROPYNOL
- CAS: 107-19-7
- EC number: 203-471-2
- MF: C3H4O
- MW: 56.06
First Aid Measures
General adviceImmediate medical attention is required. In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible).
Eye contact
| General advice | Immediate m | edical attentio | n is requir | ed. In cas | e of accident or | unwellness, | seek m |
|---|---|---|---|---|---|---|---|
| advice imme | diately (show | directions f | or use or | safety data she | et if possible | ). | |
| Eye contact | Keep eye wid | e open while | rinsing. Im | mediate | medical attentio | n is required. | Rinse |
| immediately | with plenty of | water, also | under th | e eyelids, for at | least 15 minu | tes. Do | |
| affected area | . | ||||||
| Skin Contact | Wash off imm | ediately with | plenty of w | ater. Wa | sh off immediat | ely with soap | and ple |
| water while r | emoving all c | ontaminate | d clothes | and shoes. | |||
| Inhalation | Remove to fr | esh air Call a | physician | or poison | control center i | mmediately If | not bre |
| give artificial | respiration If | breathing is | difficult, | give oxygen | |||
| Ingestion | Do NOT indu | ce vomiting. | Never give | anything | by mouth to an | unconscious | person. |
| plenty of wat | er. Immediate | medical at | tention is | required. Remo | ve from expo | sure, li | |
| Clean mouth | with water an | d drink aft | erwards p | lenty of water. | Call a physici | an or po | |
| control cente | r immediately | . | |||||
| Self-protection of the first aider | Remove all s | ources of igni | tion. |
Keep eye wide open while rinsing. Immediate medical attention is required. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Do not ru affected area.
Skin Contact
Wash off immediately with plenty of water. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation
Remove to fresh air Call a physician or poison control center immediately If not breathing, give artificial respiration If breathing is difficult, give oxygen
Ingestion
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Drink plenty of water. Immediate medical attention is required. Remove from exposure, lie down.
Clean mouth with water and drink afterwards plenty of water. Call a physician or poison control center immediately.
Self-protection of the first aider
Clean mouth with water and drink afterwards plenty of water. Call a physician or poison control center immediately.
Remove all sources of ignition.
Most important symptoms and effects, both acute and delayed
SymptomsNo information available.
Indication of any immediate medical attention and special treatment needed
Note to physiciansProduct is a corrosive material. Use of gastric lavage or emesis is contraindicated.
Possible perforation of stomach or esophagus should be investigated. Do not give chemical antidotes. Asphyxia from glottal edema may occur. Marked decrease in blood pressure may occur with moist rales, frothy sputum, and high pulse pressure. Treat symptomatically.
Possible perforation of stomach or esophagus should be investigated. Do not give chemical antidotes. Asphyxia from glottal edema may occur. Marked decrease in blood pressure may occur with moist rales, frothy sputum, and high pulse pressure. Treat symptomatically.
Suitable Extinguishing Media
Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
None.
Specific hazards arising from the chemical
Specific hazards arising from the chemicalThe product causes burns of eyes, skin and mucous membranes. Thermal decomposition can lead to release of irritating and toxic gases and vapors. In the event of fire and/or explosion do not breathe fumes.
Hazardous combustion products
Carbon oxides.
Explosion data
Sensitivity to Mechanical ImpactNo information available.
Sensitivity to Static Discharge
No information available.
Protective equipment and precautions for firefighters
Protective equipment and precautions for firefightersAs in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
NFPA 704
4
3
3
| HEALTH | 4 | Very short exposure could cause death or major residual injury (e.g. hydrogen cyanide, phosgene, methyl isocyanate, hydrofluoric acid) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 3 | Capable of detonation or explosive decomposition but requires a strong initiating source, must be heated under confinement before initiation, reacts explosively with water, or will detonate if severely shocked (e.g. ammonium nitrate, cesium, hydrogen peroxide) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal precautionsEvacuate personnel to safe areas. Remove all sources of ignition. Ensure adequate ventilation, especially in confined areas. Keep people away from and upwind of spill/leak.
Use personal protective equipment as required.
Use personal protective equipment as required.
Environmental precautions
Environmental precautionsPrevent further leakage or spillage if safe to do so. Prevent product from entering drains.
See Section 12 for additional Ecological Information.
See Section 12 for additional Ecological Information.
Methods and material for containment and cleaning up
Methods for containmentPrevent further leakage or spillage if safe to do so. Cover powder spill with plastic sheet or tarp to minimize spreading. Dike far ahead of liquid spill for later disposal.
Methods for cleaning up
Dam up. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Pick up and transfer to properly labeled containers. Take up mechanically, placing in appropriate containers for disposal. After cleaning, flush away traces with water.
Precautions for safe handling
Advice on safe handlingEnsure adequate ventilation, especially in confined areas. Keep away from heat, sparks, flame and other sources of ignition (i.e., pilot lights, electric motors and static electricity).
Take precautionary measures against static discharges. Use spark-proof tools and explosion-proof equipment. All equipment used when handling the product must be grounded. Avoid contact with skin and eyes. In case of insufficient ventilation, wear suitable respiratory equipment. Use only with adequate ventilation and in closed systems. Noxious vapor/odor.
Take precautionary measures against static discharges. Use spark-proof tools and explosion-proof equipment. All equipment used when handling the product must be grounded. Avoid contact with skin and eyes. In case of insufficient ventilation, wear suitable respiratory equipment. Use only with adequate ventilation and in closed systems. Noxious vapor/odor.
Conditions for safe storage, including any incompatibilities
Storage ConditionsKeep tightly closed in a dry and cool place. Keep in properly labeled containers. Keep containers tightly closed in a dry, cool and well-ventilated place. Store at 4 °C.
Incompatible materials
Incompatible with strong acids and bases. Incompatible with oxidizing agents.
Control parameters
Exposure Guidelines.
Other Information
Vacated limits revoked by the Court of Appeals decision in AFL-CIO v. OSHA, 965 F.2d 962 (11th Cir., 1992).
| Chemical Name | ACGIH TLV | OSHA PEL | NIOSH IDLH |
|---|---|---|---|
| Propargyl alcohol 107-19-7 | TWA: 1 ppm S* | (vacated) TWA: 1 ppm (vacated) TWA: 2 mg/m3 (vacated) S* | TWA: 1 ppm TWA: 2 mg/m3 |
Appropriate engineering controls
Engineering ControlsEnsure adequate ventilation, especially in confined areas
Individual protection measures, such as personal protective equipment
Eye/face protectionTight sealing safety goggles. Face protection shield.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended. Keep away from food, drink and animal feeding stuffs.
Contaminated work clothing should not be allowed out of the workplace. Avoid contact with skin, eyes or clothing. Take off all contaminated clothing and wash it before reuse. Wea suitable gloves and eye/face protection.
Contaminated work clothing should not be allowed out of the workplace. Avoid contact with skin, eyes or clothing. Take off all contaminated clothing and wash it before reuse. Wea suitable gloves and eye/face protection.
Information on basic physicochemical properties
- Physical Stateliquid
- AppearanceNo information available
- Odorat 100.00 %. geranium
- pH3 (20°C, 500g/L in H2O)
- Melting point/freezing point-53 °C
- Boiling point114 °C
- Flash point33 °C
- Density0.949 g/mL
- Evaporation rateNo information available
- Upper flammability limits82.6%
- Lower flammability limit1.9%
- Vapor pressure11.6 mmHg
- Vapor density1.93 (vs air)
- Specific gravityNo information available
- Water solubilitymiscible
- Solubility in other solventsNo information available
- Partition coefficientNo information available
- Autoignition temperature365 °C
- Decomposition temperatureNo information available
- Kinematic viscosityNo information available
- Explosive propertiesNo information available
- Oxidizing propertiesNo information available
- SolubilityMiscible with water, alcohol and oils, but not soluble in mineral oil, many hydrocarbons, etc
- ColourClear colorless to slightly yellow
- Upper/lower flammability or explosive limits1.9-86.2% (v/v)
Reactivity
Not applicable
Chemical stability
Stable under recommended storage conditions.
Possibility of Hazardous Reactions
None under normal processing.
Hazardous polymerization
No information available.
Conditions to avoid
Heat, flames and sparks. Exposure to air or moisture over prolonged periods.
Incompatible materials
Incompatible with strong acids and bases. Incompatible with oxidizing agents.
Hazardous Decomposition Products
Thermal decomposition can lead to release of irritating and toxic gases and vapors. Carbon oxides.
Information on likely routes of exposure
InhalationClassified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.
Information on toxicological effects
SymptomsClassified based on available data. For more details, see section 2.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic ToxicityChronic exposure to corrosive fumes/gases may cause erosion of the teeth followed by jaw necrosis. Bronchial irritation with chronic cough and frequent attacks of pneumonia are common. Gastrointestinal disturbances may also be seen. Avoid repeated exposure. Possible risk of irreversible effects. May cause adverse liver effects. Target Organ Effects Central nervous system, Respiratory system, Kidney, Liver, Skin.
Numerical measures of toxicity - Product Information
Unknown acute toxicityClassified based on available data. For more details, see section 2
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
The following values are calculated based on chapter 3.1 of the GHS document
100 mg/kg
ATEmix (dermal)
300 mg/kg
ATEmix (inhalation-dust/mist)
0.5 mg/l
ATEmix (inhalation-vapor)
1040 mg/l
Ecotoxicity
Toxic to aquatic life with long lasting effects
0% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
| Chemical Name | Algae/aquatic plants | Fish | Toxicity to Microorganisms | Crustacea |
|---|---|---|---|---|
| Propargyl alcohol 107-19-7 | - | 1.49 - 1.56: 96 h Pimephales promelas mg/L LC50 flow-through | - | 32: 24 h Daphnia magna mg/L EC50 |
Propargyl alcohol -
1.49 - 1.56: 96 h Pimephales - 32: 24 h Daphnia magna
Persistence and degradability
No information available.
Bioaccumulation
No information available.
Mobility
No information available.
Disposal of wastes
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Contaminated packaging
Do not reuse container.
Other Information
Waste codes should be assigned by the user based on the application for which the product was used.
US EPA Waste Number
P102
DOT
UN/ID noUN2929
Hazard Class
6.1
Subsidiary class
3
Packing Group
I
Proper shipping name
Toxic liquids, flammable, organic, n.o.s.
Description
UN2929, Toxic liquids, flammable, organic, n.o.s. (Propargyl alcohol), 6.1 (3), I, POISON
Emergency Response Guide Number
131
IMDG
UN/ID noUN2929
Hazard Class
6.1
Subsidiary hazard class
3
Packing Group
I
Proper shipping name
Toxic liquid, flammable, organic, n.o.s.
Description
UN2929, Toxic liquid, flammable, organic, n.o.s. (Propargyl alcohol), 6.1 (3), I, (33°C c.c.)
Special Provisions
274, 315
EmS-No
F-E, S-D
IATA
UN/ID noUN2929
Hazard Class
6.1
Subsidiary hazard class
3
Packing Group
I
Proper shipping name
Toxic liquid, flammable, organic, n.o.s.
Description
UN2929, Toxic liquid, flammable, organic, n.o.s. (Propargyl alcohol), 6.1 (3), I
International Inventories
All of the components in the product are on the following Inventory lists
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) Australia (AICS) South Korea (KECL): China (IECSC)
ENCS (Japan): Philippines (PICCS)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) Australia (AICS) South Korea (KECL): China (IECSC)
ENCS (Japan): Philippines (PICCS)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
| Chemical name | TSCA | DSL | NDSL | EINECS | ELINCS | ENCS | IECSC | KECL | PICCS | AICS |
|---|---|---|---|---|---|---|---|---|---|---|
| Propargyl alcohol | X | X | - | X | - | X | X | X | X | X |
US Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute health hazardYes
Chronic Health Hazard
Yes
Fire hazard
Yes
Sudden release of pressure hazard
No
Reactive hazard
No
CWA (Clean Water Act)
This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).
CFR 122.42).
US State Regulations
California Proposition 65
This product does not contain any Proposition 65 chemicals.
U.S. State Right-to-Know Regulations
| Chemical Name | New Jersey | Massachusetts | Pennsylvania |
|---|---|---|---|
| Propargyl alcohol 107-19-7 | X | X | X |
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.