Chemical Safety Data Sheet MSDS / SDS
Propyl chloroformate
Revision Date:2026-03-20Revision Number:1
Product identifier
- Product name: Propyl chloroformate
- CBnumber: CB9852781
- CAS: 109-61-5
- EINECS Number: 203-687-7
- Synonyms: NPCF;propyl carbonochloridate
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H331 Toxic if inhaled
H314 Causes severe skin burns and eye damage
H302 Harmful if swallowed
H225 Highly Flammable liquid and vapour
Substance
- Product name: Propyl chloroformate
- Synonyms: NPCF;propyl carbonochloridate
- CAS: 109-61-5
- EC number: 203-687-7
- MF: C4H7ClO2
- MW: 122.55
If inhaled
Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor/ physician.
In case of skin contact
Take off all contaminated clothing immediately. If on skin, rinse well with water. Call a POISON CENTER or doctor/ physician.
In case of eye contact
Rinse with plenty of water. If easy to do, remove contact lens, if worn. Immediately call a POISON CENTER or doctor/ physician.
If swallowed
Immediately call a POISON CENTER or doctor/ physician. Rinse mouth. Do NOT induce vomiting.
Most important symptoms and effects, both acute and delayed
None known.
Suitable extinguishing media
Dry powder, Dry sand, Carbon dioxide (CO2)
Unsuitable extinguishing media
Water
Specific hazards during fire fighting
No information available.
Specific extinguishing methods
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Immediately evacuate personnel to safe areas. Remove undamaged containers from fire area if it is safe to do so.
Special protective equipment for fire-fighters
Use personal protective equipment.
Personal precautions, protective equipment and emergency procedures
Wear suitable protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Environmental precautions
Prevent product from entering drains.
Methods and materials for containment and cleaning up
Collect as much of the spill as possible with a suitable absorbent material.
Handling
Technical measuresPrevent generation of vapor or mist. Take precautionary measures against static discharge. Use explosion-proof equipment.
Local/Total ventilation
Ensure adequate ventilation. Handle product only in closed system or provide appropriate exhaust ventilation at machinery. Use a local exhaust ventilation.
Advice on safe handling
Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not subject to grinding, shock or friction. Wash hands and face thoroughly after handling. Open drum carefully as content may be under pressure.
Avoidance of contact
Oxidizing agents, Acids, Strong bases, water, Amines
Storage
Conditions for safe storageKeep container tightly closed. Store in a refrigerator. Keep in a well-ventilated place. Use explosion-proof equipment. Protect from moisture. Keep under inert gas. Store locked up.
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
Engineering measures
Install a closed system or local exhaust.
Also install safety shower and eye bath.
Also install safety shower and eye bath.
Personal protective equipment
Respiratory protectionGas mask
Self-contained breathing apparatus
Eye/face protection
Self-contained breathing apparatus
Safety glasses
Safety goggles
Face-shield
Skin and body protection
Safety goggles
Face-shield
Impervious protective clothing
Hand protection
Impervious gloves *Use personal protective equipment(PPE) approved under appropriate government standards and follow local and national regulations.
Information on basic physicochemical properties
- Molecular weight122.55 g/mol
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterNo data available
- Solubility in other solventscompletely miscible Solvent: Ether completely miscible Solvent: Benzene completely miscible Solvent: Chloroform
- Water solubilityinsoluble
- Solubility(ies)benzene: miscible(lit.)
- Relative density1.09
- Relative vapor density4.2
- Vapor pressure2.7 kPa (25 °C)
- Lower explosion limit / Lower flammability limitNo data available
- Upper explosion limit / Upper flammability limitNo data available
- Dielectric constant11.2（20℃）
- Physical stateOil
- FlammabilityNo data available
- Evaporation rateNo data available
- Flash point28 °C
- Boiling point/boiling range115 °C
- Melting point/freezing pointNo data available
- pHNo data available
- Odor ThresholdNo data available
- OdorNo data available
- Colorcolorless - yellow
- Appearanceliquid
Reactivity
No data available
Chemical stability
Stable under normal conditions.
Possibility of hazardous reactions
Decomposes in contact with water and liberates toxic gases.
Conditions to avoid
Heat. Electrical spark Open flame Electrostatic discharge Exposure to moisture.
Incompatible materials
Oxidizing agents, Acids, Strong bases, water, Amines
Hazardous decomposition products
Carbon monoxide, Carbon dioxide (CO2), Hydrogen chloride gas
Acute toxicity
Product
Acute oral toxicity
Assessment: The component/mixture is moderately toxic after single ingestion.
Acute inhalation toxicity
Assessment: The component/mixture is highly toxic after short term inhalation.
Components
Propyl Chloroformate
Acute oral toxicity
LD50 (Mouse): 650 mg/kg Assessment: The component/mixture is moderately toxic after single ingestion.
Acute inhalation toxicity
LC50 (Mouse): 319 ppm Exposure time: 1 h Test atmosphere: gas Assessment: The component/mixture is highly toxic after short term inhalation.
Acute dermal toxicity
LD50 (Mouse): > 10 mg/kg Assessment: The substance or mixture has no acute dermal toxicity
Skin corrosion/irritation
Product
Result
Causes burns.
Components
Propyl Chloroformate
Result
Causes burns.
Serious eye damage/eye irritation
Product
Result
Irreversible effects on the eye
Components
Propyl Chloroformate
Result
Irreversible effects on the eye
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2.
Germ cell mutagenicity
Classified based on available data. For more details, see section 2.
Carcinogenicity
Classified based on available data. For more details, see section 2.
Reproductive toxicity
Classified based on available data. For more details, see section 2.
STOT-single exposure
Product
Target Organs
Respiratory system
Assessment
May cause damage to organs.
Components
Propyl Chloroformate
Target Organs
Respiratory system
Assessment
May cause damage to organs.
STOT-repeated exposure
Classified based on available data. For more details, see section 2.
Repeated dose toxicity
Classified based on available data. For more details, see section 2.
Aspiration toxicity
Classified based on available data. For more details, see section 2.
RTECS No.
LQ6830000 (Propyl Chloroformate)
Ecotoxicity
No data available
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Other adverse effects
No data available
Disposal methods
Waste from residuesDisposal in accordance with local and national regulations. Take precautions against ignition or explode. Entrust disposal to a licensed waste disposal company.
Contaminated packaging
Disposal in accordance with local and national regulations. Before disposal of used container, remove contents completely.
International Regulations
IATA-DGR
Not permitted for transport
IMDG-Code
UN numberUN 2740
Proper shipping name
n-PROPYL CHLOROFORMATE
Class
6.1
Subsidiary risk
3, 8
Packing group
I
EmS Code
F-E, S-C
Domestic regulation
GB 6944/12268
UN numberUN 2740
Proper shipping name
N-PROPYL CHLOROFORMATE
Class
6.1
Subsidiary risk
3, 8
Packing group
I
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous ChemicalsListed
The ingredients of this product are reported in the following inventories
CH BAGREGOn the inventory, or in compliance with the inventory
TSCA
All substances listed as active on the TSCA inventory
AICS
Not in compliance with the inventory
DSL
None of the components of this product are on the Canadian DSL, but all are on the NDSL
Propyl Chloroformate
ENCS
Propyl Chloroformate
On the inventory, or in compliance with the inventory
ISHL
On the inventory, or in compliance with the inventory
KECI
On the inventory, or in compliance with the inventory
PICCS
On the inventory, or in compliance with the inventory
IECSC
On the inventory, or in compliance with the inventory
NZIoC
Not in compliance with the inventory
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.