11.1 Information on toxicological effects
Acute toxicity
Acute toxicity estimate Oral - 500 mg/kg (Expert judgment)
Inhalation: No data available
Acute toxicity estimate Dermal - 300 mg/kg (Expert judgment)
Skin corrosion/irritation
Skin - Rabbit
Result: Moderate skin irritation
Remarks: (ECHA)
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: positive (OECD Test Guideline 429)
Germ cell mutagenicity
Suspected of causing genetic defects.
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: without metabolic activation
Method: OECD Test Guideline 490
Result: positive
Test Type: Chromosome aberration test in vitro
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Result: positive
Remarks: (ECHA)
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Result: positive
Remarks: (ECHA)
Carcinogenicity
Presumed to have carcinogenic potential for humans
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: VH1050000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated., burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting