11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Mouse - > 3,000 mg/kg
Remarks: (RTECS)
The value is given in analogy to the following substances: sodium formate
LD50 Inhalation - Rat - male and female - 4 h - > 0.67 mg/l - dust/mist (US-EPA)
Remarks: The value is given in analogy to the following substances: sodium for- mate
LD50 Dermal - Rat - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Remarks: The value is given in analogy to the following substances: sodium for- mate
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation (OECD Test Guideline 404)
Remarks: The value is given in analogy to the following substances: sodium for- mate
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Remarks: The value is given in analogy to the following substances: sodium for- mate
Respiratory or skin sensitization
Maximisation Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Remarks: The value is given in analogy to the following substances: sodium for- mate
Germ cell mutagenicity
Test Type: In vitro mammalian cell gene mutation test
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: The value is given in analogy to the following substances: sodium for- mateTest Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 473
Result: negative
Remarks: The value is given in analogy to the following substances: sodium for- mateTest Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: The value is given in analogy to the following substances: sodium for- mate
Test Type: Genotoxicity in vivo
Species: Drosophila melanogaster
Application Route: Oral
Method: OECD Test Guideline 477
Result: negative
Remarks: The value is given in analogy to the following substances: sodium for- mate
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 13 Weeks - No observed adverse effect level - 600 mg/kg
Remarks: The value is given in analogy to the following substances: sodium for- mate
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.