Chemical Safety Data Sheet MSDS / SDS
Tributylamine
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Tributylamine
- CBnumber: CB5124462
- CAS: 102-82-9
- EINECS Number: 203-058-7
- Synonyms: TRIBUTYLAMINE;TRI-N-BUTYLAMINE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P314 Get medical advice/attention if you feel unwell.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P262 Do not get in eyes, on skin, or on clothing.
Hazard statements
H372 Causes damage to organs through prolonged or repeated exposure
H315 Causes skin irritation
H302 Harmful if swallowed
Substance
- Product name: Tributylamine
- Synonyms: TRIBUTYLAMINE;TRI-N-BUTYLAMINE
- CAS: 102-82-9
- EC number: 203-058-7
- MF: C12H27N
- MW: 185.35
4.1 Description of first-aid measures
General adviceFirst aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaCarbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Nitrogen oxides (NOx)
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Nitrogen oxides (NOx)
Combustible.
Vapors are heavier than air and may spread along floors.
Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
3
2
0
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
hygroscopic
Storage class
hygroscopic
Storage class (TRGS 510): 6.1A: Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
8.1 Control parameters
Ingredients with workplace control parametersContains no substances with occupational exposure limit values.
Derived No Effect Level (DNEL)
| ['Application Area', 'Routes of\nexposure', 'Health effect', 'Value'] |
|---|
| ['Sea water', '0.00036 mg/l'] | ['Fresh water', '0.0036 mg/l'] | ['Sea sediment', '1.69 mg/kg'] | ['Fresh water sediment', '16.9 mg/kg'] | ['Sewage treatment plant', '100 mg/l'] | ['Aquatic intermittent release', '0.036 mg/l'] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.4 mm
Break through time: 480 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 30 min
Material tested:Butoject® (KCL 898)
Body Protection
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.4 mm
Break through time: 480 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: butyl-rubber
Minimum layer thickness: 0.7 mm
Break through time: 30 min
Material tested:Butoject® (KCL 898)
protective clothing
Respiratory protection
required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical stateclear, liquid
- b) Colorcolorless
- c) Odorunpleasant
- d) Melting point/freezing pointMelting point/range: -70 °C - lit.
- e) Initial boiling point and boiling range216 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 6 %(V)
Lower explosion limit: 1.4 %(V) - h) Flash point63 °C - closed cup
- i) Autoignition temperature210 °C at 1,015 hPa - DIN 51794
- j) Decomposition temperatureNo data available
- k) pH10.2 at 0.1 g/l at 25 °C - DIN 19268
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: 1.4 mPa.s at 20 °C - ASTM D 445 - m) Water solubility0.08 g/l at 20 °C - OECD Test Guideline 105- slightly soluble
- n) Partition coefficient n-octanol/waterlog Pow: 3.338 at 25 °C - Bioaccumulation is not expected.
- o) Vapor pressure3.2 hPa at 55 °C
- p) Density0.777 g/cm3 at 25 °C - lit.
- Relative density0.778 g/mL at 25 °C(lit.)
- q) Relative vapor density6.38 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- Solubilitysparingly soluble in water; soluble in most organic solvents; soluble in acetone and benzene; very soluble in alcohol and ether
- Dielectric constant2.29
9.2 Other safety information
Surface tension55 mN/m at 0.07g/l at 20 °C - OECD Test Guideline 115
Dissociation constant 10.89 at 25 °C - OECD Test Guideline 112
Relative vapor density
Dissociation constant 10.89 at 25 °C - OECD Test Guideline 112
6.4 - (Air = 1.0)
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Caution! In contact with nitrites, nitrates, nitrous acid possible liberation of nitrosamines!
Violent reactions possible with:
Oxidizing agents peroxi compounds acids
Risk of explosion with:
Mercury
Violent reactions possible with:
Oxidizing agents peroxi compounds acids
Risk of explosion with:
Mercury
10.3 Conditions to avoid
Avoid moisture.
Strong heating.
Strong heating.
10.4 Incompatible materials
Aluminum, bronze, Copper, brass, Zinc
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male - 420 mg/kg
Remarks: (ECHA)
Symptoms: After swallowing: irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract., Risk of perforation!, Risk of aspiration upon vomiting., Pulmonary failure possible after aspiration of vomit.
LC50 Inhalation - Rat - male and female - 4 h - 0.5 mg/l - vapor (OECD Test Guideline 403)
Symptoms: Irritation symptoms in the respiratory tract., Possible damages:, Lung edema,
Symptoms may be delayed.
LD50 Dermal - Rabbit - male - 195 mg/kg
Remarks: (ECHA)
Skin corrosion/irritation
Remarks: (ECHA)
Symptoms: After swallowing: irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract., Risk of perforation!, Risk of aspiration upon vomiting., Pulmonary failure possible after aspiration of vomit.
LC50 Inhalation - Rat - male and female - 4 h - 0.5 mg/l - vapor (OECD Test Guideline 403)
Symptoms: Irritation symptoms in the respiratory tract., Possible damages:, Lung edema,
Symptoms may be delayed.
LD50 Dermal - Rabbit - male - 195 mg/kg
Remarks: (ECHA)
Skin - Rabbit
Result: Irritating to skin. - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: Irritating to skin. - 4 h (OECD Test Guideline 404)
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
Result: No eye irritation (OECD Test Guideline 405)
Buehler Test - Guinea pig
Result: negative (US-EPA)
Germ cell mutagenicity
Result: negative (US-EPA)
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Oral
Method: OECD Test Guideline 474
Result: negative
Carcinogenicity
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Oral
Method: OECD Test Guideline 474
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
RTECS: YA0350000
CNS stimulation.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
CNS stimulation.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
12.1 Toxicity
No data available
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - 8 mg/l - 48 h and other aquatic (OECD Test Guideline 202) invertebrates
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - 10.1 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test NOEC - Bacteria - 100 mg/l - 2 h
Remarks: (ECHA)
Toxicity to daphnia semi-static test EC50 - Daphnia magna (Water flea) - 8 mg/l - 48 h and other aquatic (OECD Test Guideline 202) invertebrates
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - 10.1 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test NOEC - Bacteria - 100 mg/l - 2 h
Remarks: (ECHA)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 88 % - Readily biodegradable.
(OECD Test Guideline 301B)
Result: 88 % - Readily biodegradable.
(OECD Test Guideline 301B)
12.3 Bioaccumulative potential
Bioaccumulation Cyprinus carpio (Carp) - 28 d - 0.1 mg/l(Tris-n-butylamine)
Bioconcentration factor (BCF): 7.3 (OECD Test Guideline 305)
Bioconcentration factor (BCF): 7.3 (OECD Test Guideline 305)
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
Biological effects:
Harmful effect due to pH shift. Forms corrosive mixtures with water even if diluted.
Discharge into the environment must be avoided.
Harmful effect due to pH shift. Forms corrosive mixtures with water even if diluted.
Discharge into the environment must be avoided.
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 2542
IMDG: 2542
IATA-DGR: 2542
IMDG: 2542
IATA-DGR: 2542
14.2 UN proper shipping name
ADR/RID: TRIBUTYLAMINE
IMDG: TRIBUTYLAMINE
IATA-DGR: Tributylamine
IMDG: TRIBUTYLAMINE
IATA-DGR: Tributylamine
14.3 Transport hazard class(es)
ADR/RID: 6.1
IMDG: 6.1
IATA-DGR: 6.1
IMDG: 6.1
IATA-DGR: 6.1
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
Aluminum, bronze, Copper, brass, Zinc
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.