11.1 Information on toxicological effects
Acute toxicity
Acute toxicity estimate Oral - 220 mg/kg (Acute toxicity estimate according to Regulation (EC) No. 1272/2008)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Acute toxicity estimate Inhalation - 0.05 mg/l - dust/mist (Acute toxicity estimate according to Regulation (EC) No. 1272/2008)
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
LC50 Dermal - Rat - male and female - > 2,500 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Skin - in vitro assay
Result: No skin irritation - 15 min
Remarks: (ECHA)
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Maximisation Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Suspected of causing genetic defects.
Test Type: Micronucleus test
Species: Mouse
Cell type: Red blood cells (erythrocytes)
Application Route: Inhalation
Method: OECD Test Guideline 474
Result: negative
Test Type: Transgenic rodent somatic cell gene mutation assay
Species: Mouse
Application Route: Inhalation
Method: OECD Test Guideline 488
Result: negative
Test Type: comet assay
Species: Mouse
Application Route: Inhalation
Result: negative
Remarks: (ECHA)
Carcinogenicity
Presumed to have carcinogenic potential for humans
Reproductive toxicity
Suspected of damaging the unborn child.
Suspected of damaging fertility.
Studies indicating a hazard to babies during the lactation period
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation. - Respiratory Tract
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure.
- Respiratory Tract
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Vanadium and its compounds generally cause irritations after eye and skin contact and mucosal irritations, coughing, and dyspnoea after inhalation. After absorption of toxic quantities changes in the blood picture, loss of weight, cardiovascular com- plaints.
Other dangerous properties can not be excluded.
This substance should be handled with particular care.