1,4-Dioxane

Melting point :12 °C
Boiling point :101 °C
Density :1.034 g/mL at 25 °C(lit.)
vapor density :3 (vs air)
vapor pressure :27 mm Hg ( 20 °C)
refractive index :n20/D 1.422(lit.)
Flash point :54 °F
storage temp. :room temp
solubility :Soluble in acetone, alcohol, benzene, and ether (Weast, 1986). Miscible with most organic solvents (Huntress and Mulliken, 1941) including 2-methylpropanol, toluene, cychexanone, and cyclopentanone.
form :Solution
color :APHA: ≤20
Odor :Mild ether-like odor detectable at 0.8 to 172 ppm (mean = 12 ppm)
PH :6-8 (500g/l, H2O, 20℃)
explosive limit :1.7-25.2%(V)
Water Solubility :SOLUBLE
Thermal Conductivity :0.162 W/(m·K) at 25 ℃
Sensitive :Hygroscopic
λmax :λ: 220 nm Amax: ≤0.70
λ: 235 nm Amax: ≤0.50
λ: 250 nm Amax: ≤0.20
λ: 270 nm Amax: ≤0.10
λ: 295-400 nm Amax: ≤0.01 Merck :14,3300
BRN :102551
Henry's Law Constant :4.89(x 10^-6 atmm³/mol) (static headspace-GC, Welke et al., 1998)
Dielectric constant :2.2（25℃）
Exposure limits :TLV-TWA 25 ppm (≈90 mg/m³) (ACGIH), 100 ppm (MSHA and OSHA); carcinogenicity: Animal Sufficient Evidence (IARC).
Stability :Stable. Incompatible with oxidizing agents, oxygen, halogens, reducing agents, moisture. Highly flammable - note wide explosive range. May form explosive peroxides in storage (rate of formation increased by heating, evaporation or exposure to light).
InChI :1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
InChIKey :RYHBNJHYFVUHQT-UHFFFAOYSA-N
SMILES :C1COCCO1
LogP :-0.42 at 20℃
Surface tension :32.71mN/m at 293.15K
CAS DataBase Reference :123-91-1(CAS DataBase Reference)
IARC :2B (Vol. 11, Sup 7, 71) 1999
NIST Chemistry Reference :1,4-Dioxane(123-91-1)
EPA Substance Registry System :1,4-Dioxane (123-91-1)
ECETOC JACC REPORT :1,4-Dioxane (123-91-1)

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312 H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362 H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312 H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501 H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501 H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501 H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:	P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233 Keep container tightly closed. P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. P242 Use only non-sparking tools. P243 Take precautionary measures against static discharge. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash hands thoroughly after handling. P264 Wash skin thouroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313 IF SKIN irritation occurs: Get medical advice/attention. P337+P313 IF eye irritation persists: Get medical advice/attention. P370+P378 In case of fire: Use … for extinction. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. P501 Dispose of contents/container to..…