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ChemicalBook >> CAS DataBase List >> 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride price.
  • $8 - $1224
  • Product name: 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride
  • CAS: 1628047-87-9
  • MF: C19H28Cl2N2
  • MW: 355.35
  • EINECS:
  • MDL Number:MFCD28334264
  • Synonyms:1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride;ABT199 intermediate1;abt199 int 1;1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine dihydrochloride;1-((4'-chloro-5,5-demethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl-2yl]methyl)piperazine dihydrochloride;1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride;Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-, hydrochloride (1:2);1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrah ydro-[1,1'-biphenyl]-2-yl)methy)piperazine dihydrochloride
Price29 Properties Safety Information Description
29 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • Synthonix
  • TRC
  • Usbiological
Package
  • 5MG
  • 50mg
  • 250.00mg
  • 250mg
  • 1g
  • 1.00g
  • 2.5g
  • 5g
  • 10g
  • 25g
  • 50g
  • 100g
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97%
  • Packaging250mg
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 98%(HPLC)
  • Packaging1g
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97%
  • Packaging5g
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001TCO
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97%
  • Packaging25g
  • Price$32
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ11760
  • Product descriptionVenetoclaxIntermediate
  • Packaging100g
  • Price$425
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1628047879
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride
  • Packaging25g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging100g
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging5g
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging250mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging1g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA163903
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging25g
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0419415
  • Product description1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE DIHYDROCHLORIDE SALT 95.00%
  • Packaging5MG
  • Price$457.89
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105012
  • Product description1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+
  • Packaging100g
  • Price$172
  • Updated2026-05-26
  • Buy
  • ManufacturerChemenu
  • Product numberCM105012
  • Product description1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+
  • Packaging25g
  • Price$58
  • Updated2026-05-26
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11242994
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 95+%
  • Packaging10g
  • Price$94
  • Updated2026-05-26
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132846
  • Product description1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97%
  • Packaging250mg
  • Price$432
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97% 250mg $16 2026-05-28 Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 98%(HPLC) 1g $18 2026-05-28 Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97% 5g $23 2026-05-28 Buy
aablocks AA001TCO 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 97% 25g $32 2026-05-28 Buy
AK Scientific J11760 VenetoclaxIntermediate 100g $425 2021-12-16 Buy
Alichem 1628047879 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 25g $400 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 100g $339 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 5g $33 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 250mg $8 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 1g $13 2021-12-16 Buy
Ambeed A163903 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 25g $99 2021-12-16 Buy
American Custom Chemicals Corporation HCH0419415 1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE DIHYDROCHLORIDE SALT 95.00% 5MG $457.89 2021-12-16 Buy
Chemenu CM105012 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+ 100g $172 2026-05-26 Buy
Chemenu CM105012 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride 95%+ 25g $58 2026-05-26 Buy
Crysdot CD11242994 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 95+% 10g $94 2026-05-26 Buy
Matrix Scientific 132846 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazinedihydrochloride 97% 250mg $432 2021-12-16 Buy
Next Last

Properties

storage temp. :Inert atmosphere,Room Temperature
Appearance :White to off-white Solid
InChI :InChI=1S/C19H27ClN2.ClH/c1-19(2)8-7-16(14-22-11-9-21-10-12-22)18(13-19)15-3-5-17(20)6-4-15;/h3-6,21H,7-14H2,1-2H3;1H
InChIKey :NRMARNSPIXWGDD-UHFFFAOYSA-N
SMILES :C(N1CCNCC1)C1CCC(C)(C)CC=1C1C=CC(Cl)=CC=1.Cl
CAS DataBase Reference :1628047-87-9

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine Dihydrochloride is an intermediate used in the preparation of Venetoclax (A112430), which is a potent and selective BCL-2 inhibitor with potent antitumour activity while sparing platelets. Venetoclax is used to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.

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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
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