H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH
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- $121 - $961
- Product name: H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH
- CAS: 199999-60-5
- MF: C58H71N11O15S2
- MW: 1226.38
- EINECS:
- MDL Number:MFCD02259683
- Synonyms:H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH;WP9QY;TUMOR NECROSIS FACTOR-ALPHA ANTAGONIST;TNF-ALPHA ANTAGONIST;H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH, (Disulfide bond);H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH,(Disulfide bond between Cys2 and Cys 8;H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH,(DISULFIDE BOND BETWEEN CYS2 AND CYS 8;WP9QY, W9, YCWSQYLCY
5 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- Sigma-Aldrich
Package
- 500μg
- 1mg
- 5MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0005218
- Product descriptionH-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH 95.00%
- Packaging5MG
- Price$495.77
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17492
- Product descriptionTNF-α Antagonist
- Packaging500μg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17492
- Product descriptionTNF-α Antagonist
- Packaging1mg
- Price$230
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17492
- Product descriptionTNF-α Antagonist
- Packaging5mg
- Price$961
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number654255
- Product descriptionTNF-α Antagonist The TNF-α Antagonist controls the biological activity of TNF-α.
- Packaging1MG
- Price$341
- Updated2025-07-31
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | PEP0005218 | H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH 95.00% | 5MG | $495.77 | 2021-12-16 | Buy |
| Cayman Chemical | 17492 | TNF-α Antagonist | 500μg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 17492 | TNF-α Antagonist | 1mg | $230 | 2024-03-01 | Buy |
| Cayman Chemical | 17492 | TNF-α Antagonist | 5mg | $961 | 2024-03-01 | Buy |
| Sigma-Aldrich | 654255 | TNF-α Antagonist The TNF-α Antagonist controls the biological activity of TNF-α. | 1MG | $341 | 2025-07-31 | Buy |
Properties
Boiling point :1692.1±65.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-15°C
solubility :DMSO: 5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :3.05±0.10(Predicted)
color :White to off-white
Water Solubility :water: 1mg/mL
5% acetic acid: 5mg/mL Sequence :Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr (Disulfide bridge:Cys2-Cys8)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :-15°C
solubility :DMSO: 5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :3.05±0.10(Predicted)
color :White to off-white
Water Solubility :water: 1mg/mL
5% acetic acid: 5mg/mL Sequence :Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr (Disulfide bridge:Cys2-Cys8)
Safety Information
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Description
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α’s recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction.Related product price
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