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ChemicalBook >> CAS DataBase List >> (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid price.
  • $15 - $1500
  • Product name: (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
  • CAS: 20445-31-2
  • MF: C10H9F3O3
  • MW: 234.17
  • EINECS:243-829-5
  • MDL Number:MFCD00004184
  • Synonyms:(R)-(+)-MTPA,(R)-(+)-Mosher'sacid;(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%(e.e.>99.5%);(+)--Methoxy--(trifluoromethyl)phenylaceticacid(Moshersacid);(r)-(+)-à-methoxy-à-(trifluoromethyl)phenylacetic acid;(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid 99% (99%ee);(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid (99%ee);(R)-(+)-ɑ-Methoxy-ɑ-(trifluoromethyl)phenylacetic acid, 99%;(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving]
Price43 Properties Safety Information Description
43 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Activate Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Chem-Impex
  • Crysdot
  • Frontier Specialty Chemicals
  • J&W Pharmlab
  • Matrix Scientific
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
Package
  • 100mg
  • 0.1g
  • 250mg
  • 500mg
  • 1.00g
  • 1g
  • 5.00g
  • 5g
  • 25G
  • 250 mg
  • Manufactureraablocks
  • Product numberAA00I3SG
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97%
  • Packaging250mg
  • Price$30
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I3SG
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97%
  • Packaging1g
  • Price$43
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I3SG
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97%
  • Packaging100mg
  • Price$15
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA00I3SG
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97%
  • Packaging5g
  • Price$200
  • Updated2026-05-29
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberW165020
  • Product description(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid 97%
  • Packaging5G
  • Price$315
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberW165020
  • Product description(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid 97%
  • Packaging25G
  • Price$1500
  • Updated2026-05-27
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS120583
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 97%EE
  • Packaging25g
  • Price$1474
  • Updated2026-06-04
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS120583
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 97%EE
  • Packaging5g
  • Price$496
  • Updated2026-06-04
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS120583
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 97%EE
  • Packaging1g
  • Price$112
  • Updated2026-06-04
  • Buy
  • ManufacturerAlichem
  • Product number20445312
  • Product description(R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoicacid
  • Packaging5g
  • Price$357
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0066115
  • Product description(+)-MTPA 95.00%
  • Packaging250MG
  • Price$599.33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0066115
  • Product description(+)-MTPA 95.00%
  • Packaging5G
  • Price$1005.43
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC5063C
  • Product description(2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid 99%
  • Packaging5g
  • Price$307
  • Updated2026-06-04
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC5063C
  • Product description(2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid 99%
  • Packaging1g
  • Price$69
  • Updated2026-06-04
  • Buy
  • ManufacturerChem-Impex
  • Product number37539
  • Product description(R)-(+)-α-Methoxy-a-(trifluoromethyl)phenylacetic acid [Optical Resolving] ≥99%(Assay)
  • Packaging1G
  • Price$102.85
  • Updated2026-05-19
  • Buy
  • ManufacturerChem-Impex
  • Product number37539
  • Product description(R)-(+)-α-Methoxy-a-(trifluoromethyl)phenylacetic acid [Optical Resolving] ≥99%(Assay)
  • Packaging5G
  • Price$381.57
  • Updated2026-05-19
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00I3SG (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 250mg $30 2026-05-29 Buy
aablocks AA00I3SG (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 1g $43 2026-05-29 Buy
aablocks AA00I3SG (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 100mg $15 2026-05-29 Buy
aablocks AA00I3SG (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid 97% 5g $200 2026-05-29 Buy
ACHEMBLOCK W165020 (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid 97% 5G $315 2026-05-27 Buy
ACHEMBLOCK W165020 (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid 97% 25G $1500 2026-05-27 Buy
Activate Scientific AS120583 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 97%EE 25g $1474 2026-06-04 Buy
Activate Scientific AS120583 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 97%EE 5g $496 2026-06-04 Buy
Activate Scientific AS120583 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 97%EE 1g $112 2026-06-04 Buy
Alichem 20445312 (R)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoicacid 5g $357 2021-12-16 Buy
American Custom Chemicals Corporation CCH0066115 (+)-MTPA 95.00% 250MG $599.33 2021-12-16 Buy
American Custom Chemicals Corporation CCH0066115 (+)-MTPA 95.00% 5G $1005.43 2021-12-16 Buy
Apolloscientific PC5063C (2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid 99% 5g $307 2026-06-04 Buy
Apolloscientific PC5063C (2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid 99% 1g $69 2026-06-04 Buy
Chem-Impex 37539 (R)-(+)-α-Methoxy-a-(trifluoromethyl)phenylacetic acid [Optical Resolving] ≥99%(Assay) 1G $102.85 2026-05-19 Buy
Chem-Impex 37539 (R)-(+)-α-Methoxy-a-(trifluoromethyl)phenylacetic acid [Optical Resolving] ≥99%(Assay) 5G $381.57 2026-05-19 Buy
Next Last

Properties

Melting point :46-49 °C(lit.)
Boiling point :105-107 °C1 mm Hg(lit.)
alpha :D25 +68.5 ± 1.3° (c = 1.49 in CH3OH)
Density :1.344 g/mL at 25 °C(lit.)
refractive index :n20/D 1.473(lit.)
Flash point :>230 °F
storage temp. :2-8°C
solubility :Soluble in methanol (50 mg/ 1 ml).
pka :1.47±0.10(Predicted)
form :Crystalline Low Melting Solid
color :White
Specific Gravity :1.344
optical activity :[α]20/D +73±1°, c = 2% in methanol
Sensitive :Hygroscopic
Merck :14,6280
BRN :2215440
InChI :1S/C10H9F3O3/c1-16-9(8(14)15,10(11,12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,14,15)/t9-/m1/s1
InChIKey :JJYKJUXBWFATTE-SECBINFHSA-N
SMILES :CO[C@@](C(O)=O)(c1ccccc1)C(F)(F)F
CAS DataBase Reference :20445-31-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is widely used reagent for determination of optical purities of alcohols and amines by 1H or 19F NMR.

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