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ChemicalBook >> CAS DataBase List >> 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione

4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione

$33 - $1286
Product name: 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione
CAS: 865854-05-3
MF: C19H14N2O2S
MW: 334.39
EINECS:640-411-8
MDL Number:MFCD18633296
Synonyms:4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione;Tideglusib(NP-031112);TIDEGLUSIB;NP-12;NP031112;Tideglusib;NP 031112;NP031112;NP-031112;1,2,4-Thiadiazolidine-3,5-dione, 2-(1-naphthalenyl)-4-(phenylmethyl)-

Price24 Properties Safety Information Description

24 prices

Selected condition：

Brand

AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
Biosynth Carbosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
TRC

Package

5MG
10mg
20mg
25mg
50mg
100mg
200mg
250mg
1g

ManufacturerAK Scientific
Product numberX5395
Product description4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione
Packaging1g
Price$1286
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0014171
Product descriptionTIDEGLUSIB 95.00%
Packaging5MG
Price$141.9
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB1539
Product descriptionTideglusib
Packaging200mg
Price$330
Updated2021-12-16
Buy

ManufacturerArctom
Product numberCFN60383
Product descriptionTideglusib ≥98%
Packaging20mg
Price$208
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberFT30356
Product descriptionTideglusib
Packaging10mg
Price$45
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberFT30356
Product descriptionTideglusib
Packaging25mg
Price$88.75
Updated2021-12-16
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ManufacturerBiosynth Carbosynth
Product numberFT30356
Product descriptionTideglusib
Packaging50mg
Price$137.5
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberFT30356
Product descriptionTideglusib
Packaging100mg
Price$225
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberFT30356
Product descriptionTideglusib
Packaging250mg
Price$375
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number16727
Product descriptionTideglusib ≥98%
Packaging5mg
Price$33
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number16727
Product descriptionTideglusib ≥98%
Packaging10mg
Price$62
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number16727
Product descriptionTideglusib ≥98%
Packaging25mg
Price$96
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number16727
Product descriptionTideglusib ≥98%
Packaging50mg
Price$129
Updated2024-03-01
Buy

ManufacturerChemenu
Product numberCM141477
Product description4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione 98%
Packaging100mg
Price$209
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0613
Product descriptionTideglusib 99.66%
Packaging10mg
Price$100
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0613
Product descriptionTideglusib 99.66%
Packaging50mg
Price$168
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	X5395	4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione	1g	$1286	2021-12-16	Buy
American Custom Chemicals Corporation	API0014171	TIDEGLUSIB 95.00%	5MG	$141.9	2021-12-16	Buy
ApexBio Technology	B1539	Tideglusib	200mg	$330	2021-12-16	Buy
Arctom	CFN60383	Tideglusib ≥98%	20mg	$208	2021-12-16	Buy
Biosynth Carbosynth	FT30356	Tideglusib	10mg	$45	2021-12-16	Buy
Biosynth Carbosynth	FT30356	Tideglusib	25mg	$88.75	2021-12-16	Buy
Biosynth Carbosynth	FT30356	Tideglusib	50mg	$137.5	2021-12-16	Buy
Biosynth Carbosynth	FT30356	Tideglusib	100mg	$225	2021-12-16	Buy
Biosynth Carbosynth	FT30356	Tideglusib	250mg	$375	2021-12-16	Buy
Cayman Chemical	16727	Tideglusib ≥98%	5mg	$33	2024-03-01	Buy
Cayman Chemical	16727	Tideglusib ≥98%	10mg	$62	2024-03-01	Buy
Cayman Chemical	16727	Tideglusib ≥98%	25mg	$96	2024-03-01	Buy
Cayman Chemical	16727	Tideglusib ≥98%	50mg	$129	2024-03-01	Buy
Chemenu	CM141477	4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione 98%	100mg	$209	2021-12-16	Buy
ChemScene	CS-0613	Tideglusib 99.66%	10mg	$100	2021-12-16	Buy
ChemScene	CS-0613	Tideglusib 99.66%	50mg	$168	2021-12-16	Buy

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Properties

Melting point :148 - 150oC
Boiling point :511.3±43.0 °C(Predicted)
Density :1.393
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
pka :-1.51±0.20(Predicted)
form :powder
color :white to beige
InChI :InChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2
InChIKey :PMJIHLSCWIDGMD-UHFFFAOYSA-N
SMILES :S1C(=O)N(CC2=CC=CC=C2)C(=O)N1C1=C2C(C=CC=C2)=CC=C1

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

Tideglusib is a thiadiazolidinone that prevents inflammation and neurodegeneration when injected into rat hippocampus concurrently with kainic acid, a compound that causes excitotoxicity. Tideglusib-induced neuroprotection, in this model, is attenuated by the PPARγ antagonist GW9662 . Interestingly, tideglusib also irreversibly inhibits glycogen synthase kinase-3β (GSK3β) with an IC50 value of 5 nM when used with a one hour preincubation, increasing to 0.1-1 μM without preincubation. Several GSK3 inhibitors, including tideglusib, promote hippocampal neurogenesis both in vitro and in vivo, suggesting suitability in Alzheimer’s therapy.

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Suppliers and manufacturers

Wuhan Nutra Biotechnology Co.,Ltd

$0.00 /10g
Tideglusib CAS:865854-05-3

Shanghai UCHEM Inc.

$143.00 /1g
Tideglusib CAS:865854-05-3

Wuhan senwayer century chemical Co.,Ltd

$0.00 /1kg
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Xi an Biohorlden Industry Trade Co Ltd

$0.00 /1g
Tideglusib CAS:865854-05-3

career henan chemical co

$1.00 /1KG
4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione CAS:865854-05-3

PT CHEM GROUP LIMITED

XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.

Henan Tianfu Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

Biochempartner

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4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione

Properties

Safety Information

Description

Related product price

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