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ChemicalBook >> CAS DataBase List >> Acarbose

Acarbose

$6 - $2245.7
Product name: Acarbose
CAS: 56180-94-0
MF: C25H43NO18
MW: 645.61
EINECS:260-030-7
MDL Number:MFCD00869592
Synonyms:Acarbose Hydrate;AMylostatin J, Bay g 5421, alpha-GHI;4)-O-a-D-glucopyranosyl-(1®D-Glucose,O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-a-D-glucopyranosyl-(1®Acarbose (Acarbosum);(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-;O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-glucose;Acarbose API

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AHH
AK Scientific
Ambeed
ApexBio Technology
Arctom
Biorbyt Ltd
Biosynth Carbosynth
Cayman Chemical
Chemenu
Chem-Impex
ChemScene
Crysdot
CSNpharm
DC Chemicals
Sigma-Aldrich
TCI Chemical
Tocris
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20mg
2g
10g
10
y0000354
200mg
y0000427
50
10mg
50mg
100mg
250mg
500mg
1g
5g
25g
50g
10mM(in 1mL DMSO)
y0000500
100g
10 mg
20 mg
100 mg

ManufacturerAHH
Product numberAPI-1392
Product descriptionAcarbose 98%
Packaging25g
Price$450
Updated2021-12-16
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ManufacturerAK Scientific
Product numberJ10300
Product descriptionAcarbose Hydrate
Packaging100mg
Price$89
Updated2021-12-16
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ManufacturerAK Scientific
Product number2193AH
Product descriptionAcarbose
Packaging5g
Price$162
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA357603
Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
Packaging50mg
Price$6
Updated2021-12-16
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ManufacturerAmbeed
Product numberA357603
Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
Packaging250mg
Price$17
Updated2021-12-16
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ManufacturerAmbeed
Product numberA357603
Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
Packaging1g
Price$33
Updated2021-12-16
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ManufacturerAmbeed
Product numberA357603
Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
Packaging5g
Price$111
Updated2021-12-16
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ManufacturerAmbeed
Product numberA357603
Product description(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%
Packaging25g
Price$386
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA2431
Product descriptionAcarbose
Packaging500mg
Price$48
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA2431
Product descriptionAcarbose
Packaging1g
Price$76
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA2431
Product descriptionAcarbose
Packaging10mM(in 1mL DMSO)
Price$130
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA2431
Product descriptionAcarbose
Packaging2g
Price$137
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberA2431
Product descriptionAcarbose
Packaging5g
Price$304
Updated2021-12-16
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ManufacturerArctom
Product numberCFN91170
Product descriptionAcarbose ≥98%
Packaging20mg
Price$40
Updated2021-12-16
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ManufacturerBiorbyt Ltd
Product numberorb573066
Product descriptionAcarbose >98%
Packaging100mg
Price$690.2
Updated2021-12-16
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ManufacturerBiorbyt Ltd
Product numberorb573066
Product descriptionAcarbose >98%
Packaging250mg
Price$1208.7
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AHH	API-1392	Acarbose 98%	25g	$450	2021-12-16	Buy
AK Scientific	J10300	Acarbose Hydrate	100mg	$89	2021-12-16	Buy
AK Scientific	2193AH	Acarbose	5g	$162	2021-12-16	Buy
Ambeed	A357603	(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%	50mg	$6	2021-12-16	Buy
Ambeed	A357603	(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%	250mg	$17	2021-12-16	Buy
Ambeed	A357603	(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%	1g	$33	2021-12-16	Buy
Ambeed	A357603	(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%	5g	$111	2021-12-16	Buy
Ambeed	A357603	(2R,3R,4R,5R)-4-(((2R,3R,4R,5S,6R)-5-(((2R,3R,4S,5S,6R)-3,4-Dihydroxy-6-methyl-5-(((1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 98+%	25g	$386	2021-12-16	Buy
ApexBio Technology	A2431	Acarbose	500mg	$48	2021-12-16	Buy
ApexBio Technology	A2431	Acarbose	1g	$76	2021-12-16	Buy
ApexBio Technology	A2431	Acarbose	10mM(in 1mL DMSO)	$130	2021-12-16	Buy
ApexBio Technology	A2431	Acarbose	2g	$137	2021-12-16	Buy
ApexBio Technology	A2431	Acarbose	5g	$304	2021-12-16	Buy
Arctom	CFN91170	Acarbose ≥98%	20mg	$40	2021-12-16	Buy
Biorbyt Ltd	orb573066	Acarbose >98%	100mg	$690.2	2021-12-16	Buy
Biorbyt Ltd	orb573066	Acarbose >98%	250mg	$1208.7	2021-12-16	Buy

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Properties

Melting point :165-170°C
alpha :D18 +165° (c = 0.4 in water)
Boiling point :675.05°C (rough estimate)
Density :1.4278 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Very soluble in water, soluble in methanol, practically insoluble in methylene chloride.
pka :12.39±0.20(Predicted)
form :Solid
color :White to Off-White
biological source :bacterial (Actinoplanes)
Water Solubility :Soluble in water.
Merck :14,18
Stability :Hygroscopic
InChIKey :XUFXOAAUWZOOIT-JMPDRRIHSA-N
LogP :-7.935 (est)
CAS DataBase Reference :56180-94-0

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Acarbose is the first identified α-glucosidase inhibitor. It has been shown to delay the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase and sucrase with IC50 values of 0.16 and 2.9 μM, respectively. It has also been shown to bind to phosphorylase kinase, potentiating its activity. In clinical trials, acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.

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Suppliers and manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

$10.00 /1KG
Acarbose CAS:56180-94-0

Sichuan Zhuoyu Yantang Technology Co., Ltd.

$0.00 /25KG
Acarbose CAS:56180-94-0

Hebei Chuanghai Biotechnology Co,.LTD

$1.90 /1KG
Acarbose CAS:56180-94-0

Changzhou Rokechem Technology Co., Ltd.

$0.00 /1Kg
Acarbose CAS:56180-94-0

Hebei Jingbo New Material Technology Co., Ltd

$9.00 /25kg
Acarbose CAS:56180-94-0

Henan Fengda Chemical Co., Ltd

$1.20 /1000kg
Acarbose CAS:56180-94-0

Hangzhou Hyper Chemicals Limited

$0.00 /1kg
Acarbose CAS:56180-94-0

Hebei Saisier Technology Co., LTD

$6.00 /1KG
Acarbose CAS:56180-94-0

Shanghai Worldyang Chemical Co.,Ltd.

Linyi Changqing Chemical Co., LTD

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Acarbose

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