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ChemicalBook >> CAS DataBase List >> Afimoxifene

Afimoxifene

Afimoxifene price.
  • $32 - $2523
  • Product name: Afimoxifene
  • CAS: 68392-35-8
  • MF: C26H29NO2
  • MW: 387.51
  • EINECS:
  • MDL Number:
  • Synonyms:AFIMOXIFENE;4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;4-Hydroxytamoxifen, (E)-isomer;4-Hydroxytamoxifen, (Z)-isomer;4-Monohydroxytamoxifen;4-Oht hydrotamoxifen;C016601;(E/Z)-4-Hydroxy Tamoxifen
63 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 10mM*1mLinDMSO
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1000mg
  • 1G
  • 1ml
  • 5G
  • Manufactureraablocks
  • Product numberAA00FAW4
  • Product description4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol ≥98%(mixtureofisomers)
  • Packaging5mg
  • Price$42
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FAW4
  • Product description4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
  • Packaging10mg
  • Price$78
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FAW4
  • Product description4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
  • Packaging25mg
  • Price$124
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FAW4
  • Product description4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
  • Packaging50mg
  • Price$191
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00FAW4
  • Product description4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
  • Packaging100mg
  • Price$283
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging1G
  • Price$950
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging1G
  • Price$950
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging5G
  • Price$2150
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging5G
  • Price$2150
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging100MG
  • Price$295
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging100MG
  • Price$295
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging25MG
  • Price$125
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging25MG
  • Price$125
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging5MG
  • Price$40
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberS86608
  • Product description(E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98%
  • Packaging5MG
  • Price$40
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-H0471-L001
  • Product description4-Hydroxytamoxifen solution (5 mg/ml in ethanol:isopropanol (95:5)) ≥98%(HPLC)
  • Packaging1ml
  • Price$150
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FAW4 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol ≥98%(mixtureofisomers) 5mg $42 2026-05-28 Buy
aablocks AA00FAW4 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 10mg $78 2026-05-28 Buy
aablocks AA00FAW4 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 25mg $124 2026-05-28 Buy
aablocks AA00FAW4 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 50mg $191 2026-05-28 Buy
aablocks AA00FAW4 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 100mg $283 2026-05-28 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 1G $950 2026-05-25 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 1G $950 2026-05-27 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 5G $2150 2026-05-25 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 5G $2150 2026-05-27 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 100MG $295 2026-05-25 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 100MG $295 2026-05-27 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 25MG $125 2026-05-25 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 25MG $125 2026-05-27 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 5MG $40 2026-05-25 Buy
ACHEMBLOCK S86608 (E/Z)-4-Hydroxytamoxifen(Afimoxifene) 98% 5MG $40 2026-05-27 Buy
Adipogen Life Sciences CDX-H0471-L001 4-Hydroxytamoxifen solution (5 mg/ml in ethanol:isopropanol (95:5)) ≥98%(HPLC) 1ml $150 2026-05-06 Buy

Properties

Melting point :135-144°C
Boiling point :514.4±50.0 °C(Predicted)
Density :1.092
storage temp. :2-8°C
solubility :methanol: soluble10mg/mL
form :solution
pka :9.38±0.15(Predicted)
color :white to off-white
Appearance :white solid
biological source :synthetic
Major Application :forensics and toxicology
pharmaceutical (small molecule) InChI :1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25-
InChIKey :ZJLDABGSDWXVGE-BDSXMVAQSA-N
SMILES :CC\C(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CC\C(c4ccccc4)=C(\c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Tamoxifen is a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer. Although it is an antagonist of ER action in breast tissue, it acts as an ER agonist in bone and blood vessels and a partial ER agonist in uterine tissues. ?(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen that is formed by the action of cytochrome P450 2D6 in human liver. It exhibits more potent estrogen agonist/antagonist activity than its parent compound and can inhibit MCF-7 and MDA-MB-231 cell proliferation with IC50 values of 27 and 18 μM, respectively. ?(E/Z)-4-hydroxy Tamoxifen has been used to stimulate LC3 lipidation and formation of autophagic vesicles in a superoxide-dependent manner.

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