Bufalin
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- $31 - $2900
- Product name: Bufalin
- CAS: 465-21-4
- MF: C24H34O4
- MW: 386.53
- EINECS:
- MDL Number:MFCD30207876
- Synonyms:22-dienolide,3,14-dihydroxy-,(3-beta,5-beta)-bufa-2 ;Bufalin, 98%, from bufonis venenum;Bufalin, >=98%;22-dienolide,3-beta,14-dihydroxy-5-beta-bufa-2 ;BUFA-20,22-DIENOLIDE, 3,14-DIHYDROXY-, (3B,5B)-;BUFALIN;(3BETA,5BETA)-3,14-DIHYDROXYBUFA-20,22-DIENOLIDE;3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE
81 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- JR MediChem
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 250mg
- 10mM*1mLinDMSO(Solution)
- 2mg
- 500mg
- 10mM*1mLinDMSO
- 1g
- 1000mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100MG
- Manufactureraablocks
- Product numberAA00I8HZ
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98%
- Packaging1mg
- Price$31
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I8HZ
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98%
- Packaging5mg
- Price$38
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I8HZ
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98%
- Packaging10mg
- Price$53
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I8HZ
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98
- Packaging25mg
- Price$127
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I8HZ
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98
- Packaging50mg
- Price$178
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106021
- Product descriptionBufalin 98.00%
- Packaging50MG
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106021
- Product descriptionBufalin 98.00%
- Packaging100MG
- Price$390
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0533-M050
- Product descriptionBufalin ≥98%(HPLC)
- Packaging50mg
- Price$240
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0533-M010
- Product descriptionBufalin ≥98%(HPLC)
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0533-M010
- Product descriptionBufalin ≥98%(HPLC)
- Packaging10mg
- Price$60
- Updated2026-05-06
- Buy
- ManufacturerAmbeed
- Product numberA206803
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
- Packaging1mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206803
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
- Packaging10mg
- Price$148
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206803
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
- Packaging5mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206803
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
- Packaging25mg
- Price$251
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206803
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
- Packaging50mg
- Price$373
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206803
- Product description5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+%
- Packaging100mg
- Price$554
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00I8HZ | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98% | 1mg | $31 | 2026-05-29 | Buy |
| aablocks | AA00I8HZ | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98% | 5mg | $38 | 2026-05-29 | Buy |
| aablocks | AA00I8HZ | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98% | 10mg | $53 | 2026-05-29 | Buy |
| aablocks | AA00I8HZ | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98 | 25mg | $127 | 2026-05-29 | Buy |
| aablocks | AA00I8HZ | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98 | 50mg | $178 | 2026-05-29 | Buy |
| ACHEMBLOCK | U106021 | Bufalin 98.00% | 50MG | $235 | 2026-05-27 | Buy |
| ACHEMBLOCK | U106021 | Bufalin 98.00% | 100MG | $390 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0533-M050 | Bufalin ≥98%(HPLC) | 50mg | $240 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0533-M010 | Bufalin ≥98%(HPLC) | 10mg | $60 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0533-M010 | Bufalin ≥98%(HPLC) | 10mg | $60 | 2026-05-06 | Buy |
| Ambeed | A206803 | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% | 1mg | $44 | 2021-12-16 | Buy |
| Ambeed | A206803 | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% | 10mg | $148 | 2021-12-16 | Buy |
| Ambeed | A206803 | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% | 5mg | $99 | 2021-12-16 | Buy |
| Ambeed | A206803 | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% | 25mg | $251 | 2021-12-16 | Buy |
| Ambeed | A206803 | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% | 50mg | $373 | 2021-12-16 | Buy |
| Ambeed | A206803 | 5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one 98+% | 100mg | $554 | 2021-12-16 | Buy |
Properties
Melting point :242-243°
alpha :D -20°
Boiling point :556.6±50.0 °C(Predicted)
Density :1.226±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO:36.0(Max Conc. mg/mL);93.14(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);64.68(Max Conc. mM)
Ethanol:27.5(Max Conc. mg/mL);71.15(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.78(Max Conc. mM) pka :15.01±0.70(Predicted)
form :White to off-white solid
color :White to off-white
Major Application :food and beverages
InChIKey :QEEBRPGZBVVINN-ONGIWDLKSA-N
SMILES :O[C@]12CC[C@H](C3=COC(C=C3)=O)[C@]1(CC[C@]1([H])[C@]3(CC[C@@H](C[C@@]3([H])CC[C@@]21[H])O)C)C
alpha :D -20°
Boiling point :556.6±50.0 °C(Predicted)
Density :1.226±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO:36.0(Max Conc. mg/mL);93.14(Max Conc. mM)
DMF:25.0(Max Conc. mg/mL);64.68(Max Conc. mM)
Ethanol:27.5(Max Conc. mg/mL);71.15(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.78(Max Conc. mM) pka :15.01±0.70(Predicted)
form :White to off-white solid
color :White to off-white
Major Application :food and beverages
InChIKey :QEEBRPGZBVVINN-ONGIWDLKSA-N
SMILES :O[C@]12CC[C@H](C3=COC(C=C3)=O)[C@]1(CC[C@]1([H])[C@]3(CC[C@@H](C[C@@]3([H])CC[C@@]21[H])O)C)C
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
Bufalin is a cardiotonic steroid first isolated from toad venom and used in traditional Asian medicine. It inhibits the Na+/K+-ATPase transporter (Kds = 42, 45, and 40 nM for the α1, α2, and α3 subunits, respectively). Intravenously administered bufalin is cleared rapidly, with a plasma half-life of 25 minutes in dogs and rats. Bufalin inhibits steroid receptor coactivator 1 (SRC-1) and SRC-3 at doses as low as 5 nM, promotes the degradation of SRC-3 protein, and inhibits cancer cell growth both in vitro and in vivo. It can also impact the action and expression of several other proteins and kinases as well as induce apoptosis in various cancer cells.Related product price
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Suppliers and manufacturers
Shanghai Standard Technology Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Shanghai Zheyan Biotech Co., Ltd.
BOC Sciences
TopScience Biochemical
Wuhan ChemNorm Biotech Co.,Ltd.
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
Bufalin
CAS:465-21-4
