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ChemicalBook >> CAS DataBase List >> CAY10597

CAY10597

CAY10597 price.
  • $79 - $759
  • Product name: CAY10597
  • CAS: 916046-55-4
  • MF: C20H14ClFN2O5
  • MW: 416.79
  • EINECS:
  • MDL Number:MFCD11976898
  • Synonyms:5-CHLORO-1'-[(2-FLUOROPHENYL)METHYL]-2,2',5'-TRIOXO-SPIRO[3H-INDOLE-3,3'-PYRROLIDINE-1(2H)-ACETIC ACID];CAY10597;2-(5-chloro-1'-(2-fluorobenzyl)-2,2',5'-trioxospiro[indoline-3,3'-pyrrolidin]-1-yl)acetic acid;Spiro[3H-indole-3,3'-pyrrolidine]-1(2H)-acetic acid, 5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-
9 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • Cayman Chemical
  • ChemScene
Package
  • 1mg
  • 5mg
  • 10mg
  • Manufactureraablocks
  • Product numberAA00GT7V
  • Product descriptionCAY10597 ≥98%
  • Packaging1mg
  • Price$79
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT7V
  • Product descriptionCAY10597 ≥98%
  • Packaging5mg
  • Price$345
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00GT7V
  • Product descriptionCAY10597 ≥98%
  • Packaging10mg
  • Price$610
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number1448AH
  • Product description5-Chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3h-indole-3,3'-pyrrolidine-1(2H)-aceticacid
  • Packaging1mg
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012539
  • Product descriptionCAY10597 ≥98%
  • Packaging5mg
  • Price$345
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012539
  • Product descriptionCAY10597 ≥98%
  • Packaging10mg
  • Price$610
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012539
  • Product descriptionCAY10597 ≥98%
  • Packaging1mg
  • Price$79
  • Updated2026-04-30
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066763
  • Product descriptionCRTh2 antagonist 4
  • Packaging5mg
  • Price$759
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066763
  • Product descriptionCRTh2 antagonist 4
  • Packaging1mg
  • Price$169
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00GT7V CAY10597 ≥98% 1mg $79 2026-05-28 Buy
aablocks AA00GT7V CAY10597 ≥98% 5mg $345 2026-05-28 Buy
aablocks AA00GT7V CAY10597 ≥98% 10mg $610 2026-05-28 Buy
AK Scientific 1448AH 5-Chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3h-indole-3,3'-pyrrolidine-1(2H)-aceticacid 1mg $176 2021-12-16 Buy
Cayman Chemical 10012539 CAY10597 ≥98% 5mg $345 2026-04-30 Buy
Cayman Chemical 10012539 CAY10597 ≥98% 10mg $610 2026-04-30 Buy
Cayman Chemical 10012539 CAY10597 ≥98% 1mg $79 2026-04-30 Buy
ChemScene CS-0066763 CRTh2 antagonist 4 5mg $759 2026-06-04 Buy
ChemScene CS-0066763 CRTh2 antagonist 4 1mg $169 2026-06-04 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 0.30 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'-pyrrolidine-1(2H)-acetic acid is a potent CRTH2/DP2 receptor antagonist (Ki = 37 nM). The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. In humans, CRTH2/DP2 is expressed on eosinophils, basophils and Th2 cells where it mediates the chemotactic activity of PGD2.